Prescribing patterns of anti-emetic drugs during pregnancy in Germany.

Abstract:

OBJECTIVES:The purpose of this study was to examine the prescribing patterns of anti-emetics for pregnant women in Germany. METHOD:A large, nation-wide German statutory sickness fund provided data of reimbursed prescriptions and personal data for all insured women giving birth between June 2000 and May 2001 (n = 41,293). The prescribed drugs were classified according to the Anatomical Therapeutic Chemical code. RESULT:About 13.9% (n = 5,746) of all pregnant women received an anti-emetic prescription. Over 98.5% of these women were treated with anti-emetics that are considered safe. But only 27.8% received the recommended anti-histamine meclozine and 2.1% the safest drug pyridoxine. CONCLUSION:As there are no official guidelines for the treatment of nausea and vomiting during pregnancy in Germany, many different drugs are used, sometimes ignoring effectiveness and even safety. Therefore, evidence-based guidelines for anti-emetic therapy are needed.

journal_name

Arch Gynecol Obstet

authors

Markl GE,Strunz-Lehner C,Egen-Lappe V,Hasford J

doi

10.1007/s00404-006-0286-0

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

461-7

issue

6

eissn

0932-0067

issn

1432-0711

journal_volume

275

pub_type

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