当前位置： SCI文献检索 > INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY期刊下所有文献 > Outbreak of Serratia marcescens colonization and infection traced to a healthcare worker with long-term carriage on the hands.

Outbreak of Serratia marcescens colonization and infection traced to a healthcare worker with long-term carriage on the hands.

Abstract：

OBJECTIVE:To reveal the source of a nosocomial outbreak of colonization and infection with a strain of Serratia marcescens positive for Guiana extended-spectrum beta-lactamase 1 (GES-1) that occurred among patients in a neurosurgical intensive care unit (ICU) in a Dutch university medical center from May 2002 through March 2003. METHODS:Samples from the environment and from the hands of healthcare workers (HCWs) were cultured. A retrospective case-control study was carried out. RESULTS:Fifteen neurosurgical ICU patients who had 1 or more cultures that yielded the epidemic strain of S. marcescens from May 2002 through March 2003 were defined as case patients and matched with 30 control patients. Environmental cultures did not reveal a prominent source of S. marcescens. Cultures of specimens from the hands of 100 HCWs revealed colonization of a single HCW with the epidemic strain. Although this HCW instantly went on leave, serial cultures detected prolonged carriage of the epidemic strain on the hands of the HCW for 3 months. The skin of the HCW's hands was psoriatic. The epidemic abruptly ended after the colonized HCW went on leave. Retrospective case-control analysis showed that the patients colonized or infected with S. marcescens received significantly more nursing care from the colonized HCW than did control patients (P<.05). From February 2004 through October 2004, a second cluster of 3 patients was detected with the epidemic strain of S. marcescens. In October 2004, the formerly colonized HCW appeared to have carriage of the epidemic strain on the hands again. CONCLUSIONS:A single HCW with the epidemic strain of S. marcescens on the hands was considered the source of this outbreak.

journal_name

Infect Control Hosp Epidemiol

journal_title

Infection control and hospital epidemiology

authors

de Vries JJ,Baas WH,van der Ploeg K,Heesink A,Degener JE,Arends JP

doi

10.1086/508818

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

1153-8

issue

eissn

0899-823X

issn

1559-6834

pii

S0195941700074890

journal_volume

pub_type

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Outbreak of Serratia marcescens colonization and infection traced to a healthcare worker with long-term carriage on the hands.