Abstract:
:Distraction osteogenesis is used to treat atrophic nonunion and focal osteomyelitis. It enhances blood vessel formation in the distracted callus and in the surrounding soft tissues. Long-term angiogenesis, however, is not well described. We hypothesized newly formed blood vessels persist in the surrounding muscles until the late consolidation period. We performed unilateral tibial lengthening in eight adult Beagles. Seven days after tibial osteotomy, we began lengthening for 30 days, following which consolidation was allowed to proceed for another 60 days. We took bilateral microangiograms of the bilateral tibialis anterior, extensor digitorum longus, and gastrocnemius muscles. We determined the blood vessel volume density and the longitudinal and transverse microangiographic scores. The number of blood vessels in specified diameter ranges was determined histologically. The blood vessel volume density of the distracted limb was higher in all three muscles. The longitudinal microangiographic score was higher for the tibialis anterior and extensor digitorum longus muscles on the distracted side, whereas the transverse microangiographic score was not higher. Histologically, the number of blood vessels less than 100 mum in diameter on the distracted side was higher in the tibialis anterior and extensor digitorum longus muscles. Our data suggest distraction osteogenesis activates angiogenesis and maintains increased vascularity until the late consolidation period.
journal_name
Clin Orthop Relat Resjournal_title
Clinical orthopaedics and related researchauthors
Ohashi S,Ohnishi I,Kageyama T,Imai K,Nakamura Kdoi
10.1097/01.blo.0000238795.82466.74subject
Has Abstractpub_date
2007-01-01 00:00:00pages
223-9eissn
0009-921Xissn
1528-1132journal_volume
454pub_type
杂志文章abstract:UNLABELLED:To determine whether inferior vena cava (IVC) filter placement protects patients with musculoskeletal tumors from fatal pulmonary embolisms (PE), we retrospectively analyzed the records of 81 patients who underwent surgery for pelvic and lower extremity malignancies. All 81 patients received an IVC filter an...
journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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更新日期:2002-12-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章,评审
doi:
更新日期:2005-07-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:10.1097/00003086-199605000-00008
更新日期:1996-05-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:10.1097/00003086-199703000-00022
更新日期:1997-03-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:
更新日期:1984-05-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
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journal_title:Clinical orthopaedics and related research
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更新日期:1992-06-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
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更新日期:1986-01-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
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更新日期:1998-07-01 00:00:00
abstract::Two hundred and twenty-one consecutive arthroscopic examinations of the knee are reviewed to establish diagnostic accuracy based on subsequent arthrotomy and the clinical course in the absence of arthrotomy. One hundred and nine knees showed an arthroscopic accuracy of 89.9 per cent at subsequent arthrotomy. Ninety-fi...
journal_title:Clinical orthopaedics and related research
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更新日期:1976-11-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
doi:
更新日期:1986-10-01 00:00:00
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journal_title:Clinical orthopaedics and related research
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更新日期:1987-05-01 00:00:00
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journal_title:Clinical orthopaedics and related research
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更新日期:1978-06-01 00:00:00
abstract::Gunshot injuries to the hand and upper extremity have been studied during military conflicts and in urban settings. Treatment concepts include identification of injured structures, aggressive surgical wound care, and reconstruction of important functional structures. There are various types of missile injuries. For si...
journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章,评审
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更新日期:2003-03-01 00:00:00