Ro52, Ro60 and La IgG autoantibody levels and Ro52 IgG subclass profiles longitudinally throughout pregnancy in congenital heart block risk pregnancies.

abstract：:Cyclophosphamide (CYC) is used in severe neuropsychiatric systemic lupus erythematosus (NPSLE), but long-term data regarding its efficacy and safety are lacking. We identified NPSLE cases who received CYC from two centres during the period 1999-2013 and had regular follow-up. General and neuropsychiatric outcome at la...

journal_title：Lupus

authors： Fanouriakis A,Pamfil C,Sidiropoulos P,Damian L,Flestea A,Gusetu G,Rednic S,Bertsias G,Boumpas DT

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the correlation and agreement of spot urine protein/creatinine (P/C) ratio with 24 h proteinuria in patients with lupus nephritis (LN) under different scores of activity index (AI). METHODS:In total, 90 pairs of 24 h urine and spot urine samples from 90 patients with bi...

journal_title：Lupus

authors： Zhang Q,Sun L,Jin L

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:For patients with chronic illnesses the global burden of illness is a crucial health measure hitherto neglected in research studies and clinical practice. We tested the application and validity of PRISM (Pictorial Representation of Illness and Self-Measure), a novel visual method for assessing the burden of i...

journal_title：Lupus

authors： Büchi S,Villiger P,Kauer Y,Klaghofer R,Sensky T,Stoll T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The objective of this paper is to assess the role of gender on survival rate and causes of death and organ damage in systemic lupus erythematosus (SLE) patients in China from 2009 to 2015. METHODS:We conducted a multicenter cohort study to analyze the differences in outcome data between male and female SLE p...

journal_title：Lupus

authors： Zhang S,Ye Z,Li C,Li Z,Li X,Wu L,Liu S,Zuo X,Zhu P,Wang Z,Wang Y,Wang Z,Zhao J,Wang Q,Tian X,Li M,Zeng X

更新日期：2019-04-01 00:00:00

abstract：:Cells traffic in both directions between the fetus and the mother during pregnancy. Recent studies indicate that a low level of fetal cells commonly persists in the maternal circulation for years after pregnancy completion. The harboring of DNA or cells from another individual at low levels is called microchimerism. C...

journal_title：Lupus

authors： Nelson JL

更新日期：2002-01-01 00:00:00

abstract：:Atherosclerosis may represent a significant cause of death and morbidity in patients with systemic lupus erythematosus. Coronary involvement is more premature in lupus patients. We present the case of a young woman diagnosed with SLE at the age of 20 years who had a myocardial infarction at age 29 years. We review the...

journal_title：Lupus

authors： Farhey Y,Hess EV

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To estimate the prevalence of pulmonary arterial hypertension (PAH) and risk factors for PAH in patients registered in the Chinese SLE Treatment and Research group (CSTAR) database, the first online registry of Chinese patients with systemic lupus erythematosus (SLE). METHODS:A prospective cross-sectional s...

journal_title：Lupus

authors： Li M,Wang Q,Zhao J,Li Z,Ye Z,Li C,Li X,Zhu P,Wang Z,Zheng Y,Li X,Zhang M,Tian Z,Liu Y,He J,Zhang F,Zhao Y,Zeng X,CSTAR co-authors.

更新日期：2014-09-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a connective tissue disease where inflammatory activity affects several organ systems. An increased risk of cardiovascular disease has been identified in these patients, even after correction for traditional risk factors. The aim of the present study was to evaluate arterial stiff...

journal_title：Lupus

authors： Bjarnegråd N,Bengtsson C,Brodszki J,Sturfelt G,Nived O,Länne T

更新日期：2006-01-01 00:00:00

abstract：:Vaccines have undoubtedly brought overwhelming benefits to mankind and are considered safe and effective. Nevertheless, they can occasionally stimulate autoantibody production or even a recently defined syndrome known as autoimmune/inflammatory syndrome induced by adjuvants (ASIA). There is scarce data regarding autoi...

journal_title：Lupus

authors： Perdan-Pirkmajer K,Thallinger GG,Snoj N,Čučnik S,Žigon P,Kveder T,Logar D,Praprotnik S,Tomšič M,Sodin-Semrl S,Ambrožič A

更新日期：2012-02-01 00:00:00

abstract：:One hundred and fifty-eight patients with SLE were prospectively studied at a tertiary referral centre in India to ascertain the prevalence and clinical profile of fibromyalgia (FM) in Indian patients with lupus. An attempt was made to determine whether socio-demographic factors or disease characteristics differ in SL...

journal_title：Lupus

authors： Handa R,Aggarwal P,Wali JP,Wig N,Dwivedi SN

更新日期：1998-01-01 00:00:00

abstract：:Involvement of the musculoskeletal system is common if not universal in the clinical course of systemic lupus erythematosus (SLE). Joint involvement on the whole does not cause major erosive disease, however, recent developments in musculoskeletal imaging show clearly the presence of significant bony and soft tissue i...

journal_title：Lupus

authors： Zoma A

更新日期：2004-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a highly heterogeneous disorder in which multiple immunologic abnormalities have been described. In this review, we thoroughly analyse the impaired T cell production of, and response to, interleukin-2 (IL-2) characteristic of patients with SLE. Since it was first reported, several...

journal_title：Lupus

authors： Crispin JC,Alcocer-Varela J

更新日期：1998-01-01 00:00:00

abstract：:Numerous drugs have been linked to the induction or exacerbation of systemic cutaneous lupus erythematosus (SCLE). This report presents the third case of the biologic abatacept as an exacerbating medication for SCLE. A 73-year old woman with a remote history of subacute cutaneous lupus and rheumatoid arthritis, well c...

journal_title：Lupus

authors： Figueredo Zamora E,Callen JP,Schadt CR

更新日期：2020-12-22 00:00:00

abstract：:We studied IgG and IgM anticardiolipin antibodies (aCL) by an ELISA method in 80 Mexican systemic lupus erythematosus (SLE) patients and 378 of their first degree relatives. Sixty five percent of SLE patients and 16% of their relatives were positive for aCL. We also determined allele and haplotype frequencies of Major...

journal_title：Lupus

authors： Granados J,Vargas-Alarcón G,Drenkard C,Andrade F,Melín-Aldana H,Alcocer-Varela J,Alarcón-Segovia D

更新日期：1997-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) is particularly dangerous in systemic lupus erythematosus (SLE), being a problem both for the differential diagnosis with disease flare and for the management of SLE flare with immunosuppressive drugs. We report on four cases of SLE with concomitant CMV infection, having some common clinical and ...

journal_title：Lupus

authors： Sebastiani GD,Iuliano A,Canofari C,Bracci M

更新日期：2019-03-01 00:00:00

abstract：:Coming from Hans Wigzell's laboratory in Uppsala, Sweden, I joined the Kunkel laboratory in 1981 to spend a post-doctoral fellowship period financed by the German Research Organization. While I initially worked with Nick Chiorazzi in an attempt to generate monoclonal antibody-secreting human B-cell hybridomas, I later...

journal_title：Lupus

authors： Kabelitz D

更新日期：2003-01-01 00:00:00

abstract：:Although challenging, developing evidence-based approaches to an early and accurate diagnosis of systemic lupus erythematosus is a key approach to preventing disease and lupus-associated morbidity and mortality. Advances in our understanding of preclinical and incomplete lupus erythematosus have enabled the identifica...

journal_title：Lupus

authors： Choi MY,Barber MR,Barber CE,Clarke AE,Fritzler MJ

更新日期：2016-07-01 00:00:00

abstract：:Criteria of organ-specific autoimmunity are fulfilled in a subset of patients with myocarditis/dilated cardiomyopathy (DCM). In particular, circulating heart-reactive autoantibodies are found in patients and symptom-free relatives. These autoantibodies are directed against multiple antigens, some of which are expresse...

journal_title：Lupus

authors： Caforio AL,Daliento L,Angelini A,Bottaro S,Vinci A,Dequal G,Tona F,Iliceto S,Thiene G,McKenna WJ

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:Creatine supplementation has emerged as a promising non-pharmacological therapeutic strategy to counteract muscle dysfunction and low lean mass in a variety of conditions, including in pediatric and rheumatic diseases. The objective of this study was to examine the efficacy and safety of creatine supplemen...

journal_title：Lupus

authors： Hayashi AP,Solis MY,Sapienza MT,Otaduy MC,de Sá Pinto AL,Silva CA,Sallum AM,Pereira RM,Gualano B

更新日期：2014-12-01 00:00:00

abstract：:With a cross sectional study of 465 consecutive systemic lupus erythematosus (SLE) patients tested for 13 autoantibodies (Aab) and two idiotypes we determined the prevalence of Aab according to disease activity, both general and at particular organ systems. Seventy seven percent of SLE sera had at least one Aab and 56...

journal_title：Lupus

authors： Villarreal GM,Drenkard C,Villa AR,Slor H,Shafrir S,Bakimer R,Shoenfeld Y,Alarcón-Segovia D

更新日期：1997-01-01 00:00:00

abstract：:The main objective of this study is to describe the presence of infections in patients with pulmonary haemorrhage and systemic lupus erythematosus. Patients with systemic lupus erythematosus and pulmonary haemorrhage were thoroughly evaluated in the first 48 hours with imaging plus bronchoscopy and bronchoalveolar flu...

journal_title：Lupus

authors： Rojas-Serrano J,Pedroza J,Regalado J,Robledo J,Reyes E,Sifuentes-Osornio J,Flores-Suárez LF

更新日期：2008-04-01 00:00:00

abstract：:This report considers the rare situation in which primary antiphospholipid syndrome (PAPS) is linked with thrombotic thrombocytopenic purpura (TTP). It describes the case of a young lady with PAPS, characterized by recurring cerebro-vascular abnormalities and marked livedo reticularis, combined with circulating antica...

journal_title：Lupus

authors： de Carvalho JF,Freitas CA,Lima IV,Leite CC,Lage LV

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:We aimed to develop a model of the illness experience for youth with systemic lupus erythematosus (SLE)/mixed connective tissue disease (MCTD). METHODS:We conducted 32 semi-structured interviews with 16 outpatient youth with SLE/MCTD, age 11 to 22 years, and their parents. We qualitatively defined key featur...

journal_title：Lupus

authors： Knight A,Vickery M,Fiks AG,Barg FK

更新日期：2016-08-01 00:00:00

abstract：:Congenital heart block (CHB) is a syndrome of uncertain pathogenesis leading to cardiac conduction disturbances in the foetus and newborns. It has been proposed that maternal antibodies transmit immunological injury in the developing foetal heart, thus causing irreversible damage of the atrioventricular node, leading ...

journal_title：Lupus

authors： Sirén MK,Julkunen H,Kaaja R,Ekblad H,Koskimies S

更新日期：1999-01-01 00:00:00

abstract：:A case of recurrent cerebral infarctions in a 42-year-old woman affected by polyarteritis nodosa and antiphospholipid syndrome is reported. Two-dimensional echocardiography revealed grossly thickened mitral valve leaflets, possibly related to the presence of antiphospholipid antibodies. Thus, an embolic source at mitr...

journal_title：Lupus

authors： Morelli S,Perrone C,Paroli M

更新日期：1998-01-01 00:00:00

abstract：:Objectives The objective of this study was to determine whether advanced MRI could provide biomarkers for diagnosis and prognosis in neuropsychiatric systemic lupus erythematosus (NPSLE). Methods Our prospective study included 28 systemic lupus erythematosus (SLE) patients with primary central NPSLE, 22 patients witho...

journal_title：Lupus

authors： Sarbu N,Toledano P,Calvo A,Roura E,Sarbu MI,Espinosa G,Lladó X,Cervera R,Bargalló N

更新日期：2017-04-01 00:00:00

abstract：:The aim of this study was to evaluate traditional risk factors for coronary artery disease (CAD), homocysteine, anti-oxidized low-density lipoprotein (anti-oxLDL), anti-lipoprotein lipase (anti-LPL) and endothelin-1 (ET-1) in patients with primary anti-phospholipid syndrome (APS), furthermore verify possible associati...

journal_title：Lupus

authors： de Souza AW,Silva NP,de Carvalho JF,D'Almeida V,Noguti MA,Sato EI

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies. Recently, a specific highly activated T helper cell subset, follicular helper T (Tfh) cell, has emerged as a key immunoregulator of germinal center (GC) formation and high-affinity antibody productio...

journal_title：Lupus

authors： Zhang X,Lindwall E,Gauthier C,Lyman J,Spencer N,Alarakhia A,Fraser A,Ing S,Chen M,Webb-Detiege T,Zakem J,Davis W,Choi YS,Quinet R

更新日期：2015-08-01 00:00:00

abstract：:Although osteoporosis has traditionally been considered a disease of women, men also incur substantial bone loss with aging, and elderly men have age-specific hip fracture incidence rates and vertebral fracture prevalence rates that are at least half those in women. Early postmenopausal bone loss (which results in the...

journal_title：Lupus

authors： Khosla S,Melton LJ 3rd,Riggs BL

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:We established a multi-centre online registry for primary Sjögren's syndrome (pSS) in China, and compared Chinese patients with those from other countries. METHODS:Data were from 87 rheumatology centres in 27 provinces. All 2986 patients had pSS according to the 2002 American-European Consensus Group or the...

journal_title：Lupus

authors： Xu D,Zhao S,Li Q,Wang YH,Zhao JL,Li MT,Zhao Y,Zeng XF

更新日期：2020-01-01 00:00:00