RETRACTED: Glutathione as a mediator of apoptotic cell signaling pathways.

Abstract:

:This article has been retracted consistent with Elsevier Policy on Article Withdrawal. Please see . The Publisher apologises for any inconvenience this may cause.

journal_name

Biochem Pharmacol

journal_title

Biochemical pharmacology

authors

Cristofanon S,Dicato M,Ghibelli L,Diederich M

doi

10.1016/j.bcp.2006.03.026

subject

Has Abstract

pub_date

2006-04-18 00:00:00

eissn

0006-2952

issn

1873-2968

pii

S0006-2952(06)00211-5

pub_type

杂志文章
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    abstract::Experiments were conducted to determine how selective inhibitors of certain cyclic nucleotide phosphodiesterase (PDE) families, namely CI-930 (PDE3 inhibitor; 3-(2H)-pyridazinone-4,5-dihydro-6-[4-(1H-imidazolyl) phenyl]-5-methyl monohydro chloride) and rolipram (PDE4 inhibitor), may affect human coronary artery smooth...

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    authors: Johnson-Mills K,Arauz E,Coffey RG,Krzanowski JJ Jr,Polson JB

    更新日期:1998-10-15 00:00:00

  • New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.

    abstract::Chemokine receptor (CKR) signaling forms the basis of essential immune cellular functions, and dysregulated CKR signaling underpins numerous disease processes of the immune system and beyond. CKRs, which belong to the seven transmembrane domain receptor (7TMR) superfamily, initiate signaling upon binding of endogenous...

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    pub_type: 杂志文章,评审

    doi:10.1016/j.bcp.2016.04.007

    authors: Kleist AB,Getschman AE,Ziarek JJ,Nevins AM,Gauthier PA,Chevigné A,Szpakowska M,Volkman BF

    更新日期:2016-08-15 00:00:00

  • Effect of food intake on the activity of liver enzymes in partially hepatectomized rats treated with tumor necrosis factor.

    abstract::After partial hepatectomy (PHx), there are significant changes in the activity of a number of enzymes in the regenerating rat liver. Administration of low doses of recombinant human tumor necrosis factor-alpha (rHu-TNF) to normal rats induces similar changes in some of the enzymes but not in others. Because certain ob...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(95)00265-2

    authors: Yasmineh WG,Beyer HS,Caspers JI,Theologides A

    更新日期:1995-10-12 00:00:00

  • Investigation of the cellular mechanism of inhibition of formyl-methionyl-leucyl-phenylalanine-induced superoxide anion generation in rat neutrophils by 2-benzyloxybenzaldehyde.

    abstract::The inhibition of formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide anion (O2(.-)) generation by 2-benzyloxybenzaldehyde (CCY1a) was investigated in rat neutrophils, and the underlying mechanism of this inhibition was assessed. CCY1a concentration-dependently inhibited O2(.-) generation (IC(50)=18.5+/-4....

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    doi:10.1016/s0006-2952(03)00006-6

    authors: Wang JP,Chang LC,Lin YL,Hsu MF,Chang CY,Huang LJ,Kuo SC

    更新日期:2003-04-01 00:00:00

  • Depression of constitutive murine cytochromes P450 by staphylococcal enterotoxin B.

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    journal_title:Biochemical pharmacology

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    doi:10.1016/s0006-2952(00)00250-1

    authors: Shedlofsky SI,Tosheva RT,Snawder JA

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  • 2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention.

    abstract::Kidney cancer, also known as renal cell carcinoma (RCC), is one of the top 10 diagnosed cancers in the USA, and the incidence is rising. Despite major improvements in drug therapy strategies, RCC remains a deadly malignancy if not found and removed in its early stages. RCC is so highly drug-resistant that no effective...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.bcp.2015.04.022

    authors: Singhal SS,Singhal J,Figarola JL,Riggs A,Horne D,Awasthi S

    更新日期:2015-08-01 00:00:00

  • Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin.

    abstract::We have recently identified hyperforin, a lipophilic constituent of the herb Hypericum perforatum (St. John's wort), as a dual inhibitor of the proinflammatory enzymes cyclooxygenase-1 and 5-lipoxygenase. The aim of the present study was to further elucidate antiinflammatory properties and respective targets of hyperf...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.bcp.2003.12.020

    authors: Feisst C,Werz O

    更新日期:2004-04-15 00:00:00

  • Drug uptake-based chemoresistance in breast cancer treatment.

    abstract::Breast cancer is the most prevalent type of tumor and the second leading cause of death due to cancer among women. Although screening methods, diagnosis and therapeutic options have improved in the last decade, chemoresistance remains an important challenge. There is evidence relating breast cancer resistance with sig...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.bcp.2020.113959

    authors: Muley H,Fadó R,Rodríguez-Rodríguez R,Casals N

    更新日期:2020-07-01 00:00:00

  • Combination of irinotecan (CPT11) and 5-fluorouracil with an analysis of cellular determinants of drug activity.

    abstract::We evaluated the combination SN38 (7-ethyl-10-hydroxycamptothecin) -5fluorouracil (5FU) +/- folinic acid (FA) on six human colon cancer cell lines expressing spontaneous sensitivity to both drugs. Tumoral parameters potentially related to drug sensitivity were investigated: topoisomerase I (topo I) cleavable complexes...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/s0006-2952(98)00205-6

    authors: Pavillard V,Formento P,Rostagno P,Formento JL,Fischel JL,Francoual M,Etienne MC,Milano G

    更新日期:1998-11-15 00:00:00

  • The role of alpha-tocopherol as a peroxyl radical scavenger in human low density lipoprotein.

    abstract::It is thought that the oxidation of low density lipoprotein (LDL) plays a key role in the pathogenesis of atherosclerosis. It is well known that lipid peroxidation reactions are propagated by peroxyl radicals and it follows, therefore, that the capacity of an individual LDL particle to scavenge these oxidants may be a...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(93)90189-4

    authors: Smith D,O'Leary VJ,Darley-Usmar VM

    更新日期:1993-06-09 00:00:00

  • Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action.

    abstract::Andrographis paniculata has long been part of the traditional herbal medicine system in Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of A. paniculata in 1951, and since 1984, andrographolide and its analogs have been scrutinized with modern drug discovery approach for anti-inf...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.bcp.2017.03.024

    authors: Tan WSD,Liao W,Zhou S,Wong WSF

    更新日期:2017-09-01 00:00:00

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    pub_type: 杂志文章

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    authors: Mascia L,Ipata PL

    更新日期:2001-07-15 00:00:00

  • Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins.

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    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.bcp.2014.12.001

    authors: Xing SQ,Zhang CG,Yuan JF,Yang HM,Zhao SD,Zhang H

    更新日期:2015-01-15 00:00:00

  • Biological activity and molecular interaction of a netropsin-acridine hybrid ligand with chromatin and topoisomerase II.

    abstract::A hybrid molecule, which combines an anilinoacridine chromophore related to the antitumour drug amsacrine (m-AMSA) and a bispyrrole moiety analogous to the antiviral agent netropsin, has been examined for its ability to bind chromatin and to modulate the activity of topoisomerase II. The results show that the presence...

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    pub_type: 杂志文章

    doi:10.1016/0006-2952(92)90564-y

    authors: Bailly C,Collyn-d'Hooghe M,Lantoine D,Fournier C,Hecquet B,Fosse P,Saucier JM,Colson P,Houssier C,Hénichart JP

    更新日期:1992-02-04 00:00:00

  • Sex differences in the diabetes-induced modulation of rat hepatic cytochrome P450 proteins.

    abstract::Sex differences in the diabetes-induced changes in hepatic cytochrome P450 proteins were investigated in rats treated with streptozotocin. Changes in specific cytochrome P450 proteins were monitored using diagnostic substrates and immunologically utilizing specific polyclonal antibodies. When expressed in terms of nmo...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(93)90066-6

    authors: Barnett CR,Rudd S,Flatt PR,Ioannides C

    更新日期:1993-01-26 00:00:00

  • Amplification of bleomycin-induced DNA cleavage at cytosine residues 3' to GGG sequences by pyrrole triamide.

    abstract::We investigated the amplification of bleomycin-induced DNA cleavage by synthetic triamides containing N-methylpyrrole (Py) and/or N-methylimidazole (Im), PyPyPy, PyPyIm, PyImPy, and PyImIm, using 32P-labeled DNA fragments obtained from the human c-Ha-ras-1 and p53 genes. Peplomycin, a bleomycin analog, plus Fe(II) cau...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/s0006-2952(00)00563-3

    authors: Hiraku Y,Oikawa S,Kuroki K,Sugiyama H,Saito I,Kawanishi S

    更新日期:2001-02-01 00:00:00

  • Cofactors in in vitro induction of apoptosis in HL60 cells by all-trans retinoic acid (ATRA).

    abstract::The aim of this study was to determine the culture conditions that could modulate the induction of apoptosis by all-trans retinoic acid (ATRA). Cell viability was evaluated by trypan blue test, differentiation by nitro blue tetrazolium test, and apoptosis by morphological analysis. ATRA induced apoptosis in HL60 cells...

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    doi:10.1016/s0006-2952(97)00345-6

    authors: Carpentier Y,Mayer P,Bobichon H,Desoize B

    更新日期:1998-01-15 00:00:00

  • Multiple effects of a new anti-inflammatory agent, timegadine, on arachidonic acid release and metabolism in neutrophils and platelets.

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    pub_type: 杂志文章

    doi:10.1016/0006-2952(82)90708-0

    authors: Ahnfelt-Rønne I,Arrigoni-Martelli E

    更新日期:1982-08-15 00:00:00

  • Inhibitory effect of ionized free intracellular calcium enhanced by ruthenium red and m-chloro-carbonylcyanide phenyl hydrazon on the evoked release of acetylcholine.

    abstract::In order to understand the relationship between the free ionized calcium concentration in the axon terminals and the transmitter release we have investigated the effect of ruthenium red (RuR) and m-chloro-carbonylcyanide phenyl hydrazon (CCCP), mitochondrial uncoupler agents on the liberation of acetylcholine from mye...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(87)90020-7

    authors: Bernath S,Vizi ES

    更新日期:1987-11-01 00:00:00

  • Stimulation of cadmium uptake by estradiol in the kidney of male rats treated with cadmium.

    abstract::The present study was carried out to analyze the sex differences in the retention of Cd in rats treated with a small amount of Cd, and its mechanisms. Cd and Zn concentrations in the kidney and liver of female rats treated with 28 nmol Cd or 1 nmole Zn were significantly higher than those in male rats. Pretreatment wi...

    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(88)90305-x

    authors: Nishiyama S,Onosaka S,Taguchi T,Konishi Y,Tanaka K,Kinebuchi H

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  • Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway.

    abstract::Catalase is an antioxidant enzyme that catalyzes mainly the transformation of hydrogen peroxide into water and oxygen. Although catalase is frequently down-regulated in tumors the underlying mechanism remains unclear. Few transcription factors have been reported to directly bind the human catalase promoter. Among them...

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    pub_type: 杂志文章

    doi:10.1016/j.bcp.2014.02.025

    authors: Glorieux C,Auquier J,Dejeans N,Sid B,Demoulin JB,Bertrand L,Verrax J,Calderon PB

    更新日期:2014-05-15 00:00:00

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    doi:10.1016/0006-2952(86)90422-3

    authors: Guenthner TM

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  • Rosuvastatin reduces platelet recruitment by inhibiting NADPH oxidase activation.

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    pub_type: 杂志文章

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    authors: Pignatelli P,Carnevale R,Di Santo S,Bartimoccia S,Nocella C,Vicario T,Loffredo L,Angelico F,Violi F

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  • Inhibition of microsomal biotransformation by a series of nitrogen and oxygen heterocyclic histamine H2-antagonists.

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    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(87)90052-9

    authors: Lindstrom TD,Whitaker GW,Pioch RP

    更新日期:1987-05-15 00:00:00

  • Deficient induction of sulfobromophthalein conjugating activity by phenobarbital in hamster liver.

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    journal_title:Biochemical pharmacology

    pub_type: 杂志文章

    doi:10.1016/0006-2952(87)90540-5

    authors: Foliot A,Touchard D,Myara A,Trivin F,Chauffert M

    更新日期:1987-08-15 00:00:00

  • Gs alpha availability to cholera toxin-catalysed ADP-ribosylation is decreased in membranes of retinoic acid-treated leukemic cell lines HL-60 and THP-1. A posttranslational effect.

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    更新日期:2008-03-15 00:00:00