Abstract:
:There is a lack of well-designed epidemiological studies of possible risk factors for repeated miscarriage. In this Swedish population-based case-control study, we investigated the association between sociodemographic and anthropometric factors, obstetric history and life-style factors, with respect to the risks of first-trimester repeated miscarriage. Information on maternal characteristics was collected through in-person interviews. Plasma blood samples were analysed for cotinine and folate concentrations. Adjusted odds ratios (OR) with 95% confidence interval [CI] were used to estimate the relative risk of repeated miscarriage. The risks of repeated miscarriage were increased for women aged > or = 35 years (adjusted OR 2.9 [95% CI 1.4, 5.8]), as well as for women aged < or = 24 years (OR 2.8 [95% CI 1.1, 6.8]). Women with a history of at least one preceding miscarriage prior to the two index pregnancies, women reporting prolonged time to conceive, and women with a history of myoma, faced a more than fourfold increased risk of repeated miscarriage. Smokers were at an increased risk of repeated miscarriage (OR 2.1 [95% CI 1.1, 4.1]). Among non-smoking women with high caffeine intake, there was an increased risk of repeated miscarriage, whereas there was no such association among smokers. Low plasma folate levels were not associated with increased risks.
journal_name
Paediatr Perinat Epidemioljournal_title
Paediatric and perinatal epidemiologyauthors
George L,Granath F,Johansson AL,Olander B,Cnattingius Sdoi
10.1111/j.1365-3016.2006.00703.xsubject
Has Abstractpub_date
2006-03-01 00:00:00pages
119-26issue
2eissn
0269-5022issn
1365-3016pii
PPE703journal_volume
20pub_type
杂志文章abstract::It is not clear to what extent ethnic differences in the term birthweight distribution are constitutional or pathological. This study explored term birthweight heterogeneity between ethnic groups and the explanatory role of constitutional and environmental factors. As part of a prospective cohort study, the Amsterdam ...
journal_title:Paediatric and perinatal epidemiology
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journal_title:Paediatric and perinatal epidemiology
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journal_title:Paediatric and perinatal epidemiology
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2000.00228.x
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pub_type: 杂志文章
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