Lipid abnormalities associated with end-stage renal disease.

Abstract:

:Patients undergoing chronic renal replacement therapy have a high incidence of dyslipidemia. In general, there are increased concentrations of triglyceride-rich apolipoprotein B-containing particles. These elevations lead to increased levels of non-high-density lipoprotein (HDL) levels. This pattern is further modified by the method of dialysis (peritoneal versus hemodialysis) and comorbidities such as diabetes. End-stage renal disease patients also demonstrate increased levels of lipoprotein(a) (Lp(a)) and oxidized low-density lipoprotein (LDL)both of which are highly atherogenic. This review focuses on the pathogenesis of these lipid abnormalities and their role in the atherosclerotic process.

journal_name

Semin Dial

journal_title

Seminars in dialysis

authors

Liu J,Rosner MH

doi

10.1111/j.1525-139X.2006.00117.x

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

32-40

issue

1

eissn

0894-0959

issn

1525-139X

pii

SDI117

journal_volume

19

pub_type

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