Abstract：
STUDY DESIGN:Cross-sectional questionnaire study. OBJECTIVES:To develop and validate a symptom-based score for neurogenic bowel dysfunction (NBD): NBD score. SETTING:University Hospital of Aarhus, Denmark. METHODS:A questionnaire including questions about background parameters (n=8), faecal incontinence (n=10), constipation (n=10), obstructed defecation (n=8), and impact on quality of life (QOL) (n=3) was sent to 589 Danish spinal cord injured (SCI) patients. The reproducibility and validity of each item was tested in 20 and 18 patients, respectively. Associations between items and impact on QOL were determined by logistic regression analysis. The NBD score was constructed from items with acceptable reproducibility and validity that were significantly associated with impact on QOL. Based on odds ratios for associations between items and impact on QOL, each item was given a corresponding number of points in the NBD score. RESULTS:A total of 424 SCI patients responded. The following 10 items met the criteria above: frequency of bowel movements (0-6 points), headache, perspiration or discomfort before or during defecation (0-2 points), tablets and drops against constipation (0-2 points each), time used for each defecation (0-7 points), frequency of digital stimulation or evacuation (0-6 points), frequency of faecal incontinence (0-13 points), medication against faecal incontinence (0-4 points), flatus incontinence (0-2 points) and perianal skin problems (0-3 points). Differences in NBD score among patients reporting no, little, some or major impact on QOL were statistically significant (all P<0.001). CONCLUSION:Based on valid and reproducible questions, we have constructed a score for NBD that is correlated to impact on QOL.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Krogh K,Christensen P,Sabroe S,Laurberg Sdoi
10.1038/sj.sc.3101887subject
Has Abstractpub_date
2006-10-01 00:00:00pages
625-31issue
10eissn
1362-4393issn
1476-5624pii
3101887journal_volume
44pub_type
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