Abstract:
CASE-REPORT:A 76-year-old woman was admitted for evaluation of esophagitis complicating limited cutaneous systemic sclerosis. Endoscopy showed persistent grade III esophagitis and an erythematous antral lesion found upon biopsy to be a lymphoma of mucosa-associated lymphoid tissue (MALT). Tests were positive for Helicobacter pylori. Moderate mucosal infiltration by endoscopic ultrasonography was the only finding from staging investigations. Six months after treatment to eradicate H. pylori, a repeat endoscopy showed no evidence of the lesion. DISCUSSION:MALT lymphomas are usually confined to the gastric wall. Gastric MALT lymphomas have a well-established association with H. pylori infection. The clinical manifestations are nonspecific. Endoscopy usually shows a focus of erythema or, less often, erosion. The diagnosis rests on histological examination of a biopsy, which shows infiltration by monoclonal cells whose immunophenotype is characteristic of marginal-zone B cells. Eradication of H. pylori is the mainstay of treatment.
journal_name
Joint Bone Spinejournal_title
Joint bone spineauthors
Arnaud L,Chryssostalis A,Terris B,Pavy S,Chaussade S,Kahan A,Allanore Ydoi
10.1016/j.jbspin.2005.01.009subject
Has Abstractpub_date
2006-01-01 00:00:00pages
105-8issue
1eissn
1297-319Xissn
1778-7254pii
S1297-319X(05)00074-6journal_volume
73pub_type
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