Donepezil for the treatment of behavioral disturbances in Alzheimer's disease: a 6-month open trial.

abstract：OBJECTIVES:This study examines different combinations of informal and formal care use of older adults and investigates whether these combinations differ in terms of need for care (physical and psychological frailty) and enabling factors for informal and formal care use (social and environmental frailty). METHODS:Using...

journal_title：Archives of gerontology and geriatrics

authors： Lambotte D,De Donder L,Van Regenmortel S,Fret B,Dury S,Smetcoren AS,Dierckx E,De Witte N,Verté D,Kardol MJM,D-SCOPE Consortium.

更新日期：2018-01-01 00:00:00

abstract：:Brain transfer rate (BTR) and brain to plasma concentration ratio (BPCR) of radiolabelled human serum albumin injected intravenously were calculated to evaluate the brain transfer of serum albumin in the cerebral cortex, the right hemi-brain and the olfactory bulb of senescence accelerated prone mice (SAMP8) and senes...

journal_title：Archives of gerontology and geriatrics

authors： Ueno M,Akiguchi I,Hosokawa M,Shinnou M,Sakamoto H,Takemura M,Higuchi K

更新日期：1997-11-01 00:00:00

abstract：:In studies carried out on 401 individuals from different Spanish regions, blood lipoprotein levels do not show a clear relationship to amounts of animal fat intake because diet habits change in old age. But in these persons there was a significant and positive correlation between actual LDL levels and animal fat intak...

journal_title：Archives of gerontology and geriatrics

authors： Velasco R,Padilla E,Pérez JC,Ruiz-Torres A

更新日期：1989-09-01 00:00:00

abstract：:The cytotoxic activity of natural killer (NK) cells under both basal and interferon (IFN)-induced conditions, as well as the proliferative response of lymphocytes to ConA in old rats treated in vivo with AL-721 have been analyzed. The low levels of basal NK cell activity present in spleen of old rats were completely r...

journal_title：Archives of gerontology and geriatrics

authors： Provinciali M,Di Stefano G,Pieri C,Fabris N

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Frailty is a clinical state of increased vulnerability from aging-associated decline. We aimed to determine if a Thai Frailty Index predicted all-cause mortality in community-dwelling older Thais when accounting for age, gender and socioeconomic status. METHODS:Data of 8195 subjects aged 60 years and over f...

journal_title：Archives of gerontology and geriatrics

authors： Srinonprasert V,Chalermsri C,Aekplakorn W

更新日期：2018-01-01 00:00:00

abstract：:Assessment of suffering is extremely important in dying end-stage dementia patients (ESDP). We have developed and examined the reliability and validity of the Mini-Suffering State Examination (MSSE), in 103 consecutive bedridden ESDP. Main outcome measures included inter-observer reliability and concurrent validity. R...

journal_title：Archives of gerontology and geriatrics

authors： Aminoff BZ,Purits E,Noy S,Adunsky A

更新日期：2004-03-01 00:00:00

abstract：:We have described twelve dementia patients with noise making. We categorized noise making into (i) persistent screaming, (ii) perseverative vocalization, (iii) continuous chattering, muttering, singing or humming, and (iv) swearing, grunting and bizarre noise-making. The patients' ages ranged from 70 to 92 years with ...

journal_title：Archives of gerontology and geriatrics

authors： Nagaratnam N,Patel I,Whelan C

更新日期：2003-05-01 00:00:00

abstract：:Frailty is a common syndrome among elderly and sensory decline may exacerbate functional decline. The hand function, the manual dexterity, the performance of the daily living skills and the social interactions are determined, in a large degree, by sensory integrity. However, hand tactile sensory deterioration has been...

journal_title：Archives of gerontology and geriatrics

authors： Vieira AI,Nogueira D,de Azevedo Reis E,da Lapa Rosado M,Vânia Nunes M,Castro-Caldas A

更新日期：2016-09-01 00:00:00

abstract：:To evaluate the capacity to perceive bitter taste in a sample of the elderly population of the Brazilian Federal District, and to investigate its association with the consumption profile of distinct food groups. A total of 255 female outpatients aged 60 years or older took part in this cross-sectional study. The follo...

journal_title：Archives of gerontology and geriatrics

authors： Colares-Bento FC,Souza VC,Toledo JO,Moraes CF,Alho CS,Lima RM,Cordova C,Nobrega OT

更新日期：2012-03-01 00:00:00

abstract：:Numerous studies have affirmed the existence of a correlation between various cardiovascular diseases and functional decline in elderly people. Not much information, however, is available concerning the overall effect of various, possibly coexisting, cardiovascular pathologies, or metabolic conditions notoriously rela...

journal_title：Archives of gerontology and geriatrics

authors： Cacciafesta M,Campana F,Trani I I,Annichiarico R,Leonetti-Luparini R,Gianni W,Cicconetti P,Piccirillo G

更新日期：2000-12-01 00:00:00

abstract：:Few studies have examined the association between perioperative blood transfusion and postoperative delirium (POD) in aged patients undergoing total hip replacement surgery. In this prospective study, 186 patients older than 65 years undergoing elective unilateral total hip replacement surgery were enrolled. Of those,...

journal_title：Archives of gerontology and geriatrics

authors： Fan YX,Liu FF,Jia M,Yang JJ,Shen JC,Zhu GM,Zhu SH,Li WY,Yang JJ,Ji MH

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Falls are the leading cause of fatal injury in geriatric patients. Nursing home falls occur at twice the rate of community falls, yet few studies have compared these groups. We hypothesized that nursing home residents admitted for fall would be sicker than their community counterparts on presentation and hav...

journal_title：Archives of gerontology and geriatrics

authors： Botwinick I,Johnson JH,Safadjou S,Cohen-Levy W,Reddy SH,McNelis J,Teperman SH,Stone ME Jr

更新日期：2016-03-01 00:00:00

abstract：:A group of 40 Calabrian centenarians (12 males, 28 females) was studied from June 1 to December 31, 1993. Their age was ranging from 100 to 107 years (mean age: 102.3 +/- 1.8 years). Clinical evaluation was performed by recording anamnestic data, an objective examination, and by assessing cognitive performance, emotio...

journal_title：Archives of gerontology and geriatrics

authors： Infusino P,Mercurio M,Galasso MA,Gareri P,Filardi A,Lacava R,Pansini L,Mattace R

更新日期：1996-01-01 00:00:00

abstract：:Well-being (WB) is a complex variable in its relation to physical health and other personal and social characteristics. The aim was to study subjective well-being (SWB) and its possible associations with traditional biomarkers of cardiovascular risk or dementia, in Swedish seniors. SWB was estimated by the Psychologic...

journal_title：Archives of gerontology and geriatrics

authors： Olsson LA,Hagnelius NO,Olsson H,Nilsson TK

更新日期：2013-03-01 00:00:00

abstract：:Beta-amyloid precursor protein (betaAPP) has been shown to be involved in cell growth regulation. In spleen, the majority of cells showing betaAPP like immunoreactivity was found in the T cell-dependent zone. In Northern blot, the expression of betaAPP was increased to reach the peak at 72 h after the treatment of phy...

journal_title：Archives of gerontology and geriatrics

authors： Suh YH,Choi W,Kim SH,Kim JS,Rhi BY,Chong YH,Woo JI,Lee KW

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Geriatric depression is now very common and leads to significant economic costs and family burden in China. Families with a depressed patient often report problematic family functioning in Western samples, and lack of social support is strongly associated with geriatric depression. However, the relationship bet...

journal_title：Archives of gerontology and geriatrics

authors： Wang J,Zhao X

更新日期：2012-11-01 00:00:00

abstract：:The aim of the present study was to investigate levels of physical activity and risk factors for inactivity in older adults living in an urban area in the interior of the Amazonas state, Brazil. Data were collected between 2013 and 2015 from 274 individuals 60 years of age or older who resided in the interior of the B...

journal_title：Archives of gerontology and geriatrics

authors： Freire Junior RC,Fernandes TG,Borges GF,Guerra RO,de Abreu DCC

更新日期：2018-01-01 00:00:00

abstract：:Age-related physiologic changes together with high prevalence of chronic illness and the use of multiple medications predispose older adults to syncope. The causes of many of these patients' syncope are unexplained and most remained symptomatic. A thoughtful diagnostic strategy is essential to pinpoint the cause in ea...

journal_title：Archives of gerontology and geriatrics

authors： Sim V,Pascual J,Woo J

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:The muscle mass decreases with age, leading to frailty and weakness; however, the role of acetylcholine receptors in this process has not been properly studied. In this article, we hypothesize that diaphragmatic as well as peripheral muscle weakness may be caused by the up-regulation of gamma and alpha 7 nic...

journal_title：Archives of gerontology and geriatrics

authors： Xie F,Min S,Liu L,Peng L,Hao X,Zhu X

更新日期：2016-07-01 00:00:00

abstract：:The charts of patients who attended a geriatric day hospital (DH) over a 16-month period were reviewed retrospectively (n = 112). Home visits were conducted on consenting patients who made gains (either functional, psychosocial or medical) according to the chart review; they (and/or their caregivers) were questioned a...

journal_title：Archives of gerontology and geriatrics

authors： Dasgupta M,Clarke NC,Brymer CD

更新日期：2005-03-01 00:00:00

abstract：:Casual blood pressure (BP) measurements may sometimes indicate the presence of cardiovascular morbidity and mortality, but the correlations between BP values and the subsequent occurrence of such complications are low. This may depend on the known inability of casual BP measurements to reflect accurately the 24-hour m...

journal_title：Archives of gerontology and geriatrics

authors： Torrisi G,De Bernardis E,Di Mauro S,Marino M,Cosentino N,Leotta C,Distefano A

更新日期：1996-01-01 00:00:00

abstract：:L-carnitine is of considerable interest because of its capacity to counteract several physiological and pathological phenomena typical of brain aging processes. We examined the effects of L-carnitine on the learning ability of old rats. 100 mg/kg per body weight per day L-carnitine was administered orally to old (21 m...

journal_title：Archives of gerontology and geriatrics

authors： Lohninger S,Strasser A,Bubna-Littitz H

更新日期：2001-06-01 00:00:00

abstract：:Older adults with joint pain and comorbidity are especially at risk of becoming functionally impaired. Therefore, we studied the frequency and severity of functional limitations and identified potential modifiable determinants that may reduce functional limitations. A prospective cohort study of older adults (≥65 year...

journal_title：Archives of gerontology and geriatrics

authors： Hermsen LA,Leone SS,Smalbrugge M,Dekker J,van der Horst HE

更新日期：2014-07-01 00:00:00

abstract：:The unexpected return of mental clarity and memory shortly before death in patients suffering from severe psychiatric and neurologic disorders, which we have called "terminal lucidity", has been reported in the medical literature over the past 250 years, but has received little attention. We review a range of terminal...

journal_title：Archives of gerontology and geriatrics

authors： Nahm M,Greyson B,Kelly EW,Haraldsson E

更新日期：2012-07-01 00:00:00

abstract：:Hypothyroidism is a common disorder in older people, and may be asymptomatic and hard to be diagnosed. The main purpose of this study was to evaluate the distribution of serum thyrotropin (thyroxin-stimulating hormone, TSH) among asymptomatic older people in Taiwan, and to evaluate the relationship between age and ser...

journal_title：Archives of gerontology and geriatrics

authors： Huang CC,Chen YC,Chen LK,Hwang SJ,Lin HD

更新日期：2010-09-01 00:00:00

abstract：:Codergocrine mesylate (dihydroergotoxine; DHET), which is an ergot derivative, has been reported to counteract some age-induced impairments in brain function, but the mechanism of these effects is not known. We examined the effect of chronic DHET administration on the somatostatinergic system in the brains of aged rat...

journal_title：Archives of gerontology and geriatrics

authors： Tanaka K,Ogawa N,Asanuma M,Hirata H,Kondo Y,Chou HH,Mori A

更新日期：1992-09-01 00:00:00

abstract：:The debate about the adoption of standard multidimensional geriatric assessment instruments is mainly due to the lack of consensus on the feasibility and requirements for such instruments by both the health and the social care professions. A tool called ValGraf was developed in the attempt to give an original answer t...

journal_title：Archives of gerontology and geriatrics

authors： Pascazio L,Morosini P,Bembich S,Nardone I,Clarici A,Barbina L,Zuttion R,Gigantesco A

更新日期：2009-05-01 00:00:00

abstract：:The present study was conducted to evaluate accuracy of a recently proposed method for estimating creatinine clearance (CLcr, ml/min) from actual body weight (ABW, kg), serum creatinine (Scr, micromol/l), and serum albumin (Alb, g/l) in elderly patients with muscle atrophy (the debilitated elderly). The recent method ...

journal_title：Archives of gerontology and geriatrics

authors： Sanaka M,Takano K,Yamamoto T,Mineshita S

更新日期：1997-11-01 00:00:00

abstract：:The present work reviews current literature and the authors' experience of carotid sinus syndrome (CSS), which is considered to be the most common cause of neurally mediated acute disorders of consciousness in the elderly. Although no definitive consensus about its nosology has yet been reached, most groups agree that...

journal_title：Archives of gerontology and geriatrics

authors： Menozzi C,Brignole M,Tomasi C,Lolli G,Bottoni N,Oddone D,Gianfranchi L

更新日期：1995-01-01 00:00:00

abstract：:We studied the relation between cholesteryl-ester transfer activity (CETA) and abdominal aortic calcification in elderly subjects. Compared with 10 young healthy subjects (mean +/- S.D. age, 27 +/-2 years) and to 26 elderly subjects without abdominal aortic calcification (79 +/- 7 years), 16 elderly patients with abdo...

journal_title：Archives of gerontology and geriatrics

authors： Miyashita Y,Morimoto S,Fukuo K,Masuyama T,Yasuda O,Koh E,Tamatani M,Nakahashi T,Ogihara T

更新日期：1993-01-01 00:00:00