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Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex.

Abstract：

:Magnesium-pyridoxal-5'-phosphate-glutamate (MPPG) has been shown to ameliorate atherosclerotic symptoms in rabbits. In vitro, MPPG in the presence of peroxides such as cholesterolhydroperoxide or cumene hydroperoxide and Mn2+ ions produces "excited states" measurable as chemiluminescence or ethylene release from 1-aminocyclopropane-1-carboxylic acid (ACC). The reactions are stimulated synergistically by unsaturated fatty acids. Pyridoxal phosphate exhibits similar properties, but can be differentiated from the activities of MPPG or the sum of the components present in MPPG.

journal_name

Biochem Pharmacol

journal_title

Biochemical pharmacology

authors

Meyer BU,Schneider W,Elstner EF

doi

10.1016/0006-2952(92)90442-l

subject

Has Abstract

pub_date

1992-08-04 00:00:00

pages

505-8

issue

3

eissn

0006-2952

issn

1873-2968

pii

0006-2952(92)90442-L

journal_volume

44

pub_type

杂志文章

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