Abstract:
INTRODUCTION:Overactive bladder (OB) is one of the no-neurogenic voiding dysfunctions whose prevalence has been precisely defined among the general population but not so among the paediatric population. Its clinical manifestations are various, and its association with other pathologies like enuresis, vesico-ureteral reflux (VUR) and recurrent infections is particularly significant in children. OB is basically managed with anticholinergic drugs. The efficacy of oxybutynin chloride has been sufficiently proved; however its dosage and side effects, although scarce in children, usually cause treatment discontinuation. OBJECTIVES:Tolterodine has been successfully used as an alternative therapy of OB in adults, however its use has not been sufficiently evaluated in children. Our objective is to determine tolterodine's efficacy and tolerability in the paediatric population suffering from OB. MATERIAL AND METHODS:A retrospective study of 72 children who were diagnosed no-neurogenic OB and who received no previous treatment. A concomitant urological pathology diagnostic protocol was applied to all cases, as well as a urodynamic test (UDT) and a neurological examination. Post-treatment UDT was performed to one group of patients. RESULTS:The mean age was 10.9 years and the children were assessed between 4 and 31 months after treatment initiation. Healing was proved through cistomanometry in 67% of the cases, there was improvement in 14% and 19% of the patients showed no changes in the UDT. Following the criteria of the International Children's Continence Society (ICCS) applied to those children with no post-treatment UDT, 51% were healed, 27% improved and 22% experienced no changes. None of the patients had to discontinue the treatment due to side effects. CONCLUSIONS:Tolterodine's tolerability and efficacy are good within the paediatric population, which turns it into an alternative to the traditional anticholinergics for the treatment of OB.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Garat Barredo JM,Caffaratti Sfulcini J,de la Peña Edoi
10.1016/s0210-4806(04)73050-8subject
Has Abstractpub_date
2004-02-01 00:00:00pages
122-8issue
2eissn
0210-4806issn
1699-7980pii
S0210-4806(04)73050-8journal_volume
28pub_type
杂志文章abstract:OBJECTIVE:Describe our initial experience in the treatment of renal lithiasis with extracorporeal lithotripsy controlled by simultaneous flexible ureterorenoscopy and combined with holmium laser lithotripsy. MATERIAL AND METHODS:We performed this novel technique in a previously selected patient with left renal lithias...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
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更新日期:2017-04-01 00:00:00
abstract::There is an increasement on the incidence of tumours within the population of renal transplanted, from three to five times over general population. Related to urological tumours, it emphasizes an increase in the incidence of the renal carcinoma, around 4,7% against 3% on general population. In this case, we present a ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
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abstract::Presentation of a review of 10 paediatric patients with tumour of the testis vitelline sack, to report our experience in the management of this pathology. Mean age was 20 months (14-32), and the interval of the study was from 1970 to 1994. After orchiectomy, 7 children were included in stage I, 1 in stage II, and 2 in...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To describe the outcome of patients diagnosed of incidental prostate adenocarcinoma managed by watchful waiting. MATERIAL AND METHODS:We included patients with PSA< 4 ng/mL or higher with previous negative biopsy, who underwent surgery for BPH being diagnosed of incidental prostate adenocarcinoma. We perform...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract::Significant conceptual changes have taken place in renal tumoral diseases over the last few years. As a result of the authors' broad institutional experience, this overall revision describes the most up-to-date clinical and diagnostic aspects of this condition. Emphasis is made on molecular staging and two variables t...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(02)72825-8
更新日期:2002-09-01 00:00:00
abstract::The coincidence of an urachal adenocarcinoma with another similar tumour in other location makes necessary to separate a true primary from a metastatic adenocarcinoma. We report the case of a 66-years-old-man with an urachal mucinous adenocarcinoma and two colonic adenocarcinoma excised in the same surgical act, showi...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract::A complete urodynamic study was carried out on 41 consecutive patients presenting in the cystomanometry a vesical filling pressure at maximum capacity higher than 30 cm H2O. Two groups were evident: group I with neurogenic etiology, and group II without an obvious neurogenic etiology. From its results it can be seen t...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::Penile fracture with urethral laceration usually presents with pain and haematoma, detumescence, erectile failure and blood loss through urethral meatus. We describe the third published case of urethrocavernous fistula following blunt penile trauma sustained durind sexual intercourse. ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(08)73987-1
更新日期:2008-11-01 00:00:00
abstract::From the Second World War onwards an amazing development in science and clinical & surgery practice has taken place: antibiotics, blood storage, cardiac surgery, organ and tissue transplant, complete joint replacement, total intravenous nutrition or minimally invasive surgery. Paradoxically, during the last two decade...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(08)73792-6
更新日期:2008-01-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(08)73958-5
更新日期:2008-10-01 00:00:00
abstract::Presentation of one case of a 40 year-old, homosexual, AIDS diagnosed male with extrapulmonary tuberculosis (lymphatic nodes) and prior history of gonococcal urethritis, brain toxoplasmosis, molluscum contagiosum and pneumonia by Pneumocystis carinii. A purpura-type lesion with inflammatory features appeared in the fo...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1993-05-01 00:00:00
abstract::Presentation of one case of renal mycosis by Aspergillus as a primary complication in one patient diagnosed with acquired immunodeficiency syndrome. The importance of conservative treatment at all costs through percutaneous drainage is underlined, specially if we considered the short life expectancy of patients who ha...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::Orbital metastasis is an unusual localization within tumoral dissemination of prostatic cancer. Similarly, it is rare that orbital metastasis might be responsible for the clinic manifestations that determine the initial diagnosis of neoplasia. We illustrate the case of a patient suffering from prostatic adernocarcinom...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(03)72974-x
更新日期:2003-07-01 00:00:00
abstract::Twenty-nine male children with urethral stenosis, with ages between 7 months and 18 years, were treated by endoscopic surgery. The etiology of their condition was trauma in 21 cases and congenital in 8. Location of the stenosis corresponded in 18 cases to membranous urethra, 7 to bulbar urethra, 2 to penial urethra wh...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:To review the outcome of bulbar urethroplasty using two stage surgical techniques. MATERIAL AND METHODS:Twenty-two of the 35 patients studied corresponded to end-to-end urethroplasty (ATT) and 13 to dorsal onlay graft (DOG) in preputial skin or oral mucosa variants. Clinical outcome was considered a failure ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2012.03.006
更新日期:2013-03-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(01)72631-9
更新日期:2001-05-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2017.12.003
更新日期:2018-06-01 00:00:00
abstract::Adenocarcinoma of the bladder is an uncommon neoplasm. Depending on its origin it is classified in: primary, secondary and urachal. Generally it grows to the density of the wall, so its clinical appearence is delayed, with the subsequent delayed diagnosis and although an agressive treatment is performed, it frequently...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(05)73236-8
更新日期:2005-03-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.4321/s0210-48062007000800019
更新日期:2007-09-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2011.06.016
更新日期:2012-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0210-4806(05)73246-0
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章,多中心研究
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更新日期:2014-06-01 00:00:00
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journal_title:Actas urologicas espanolas
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更新日期:2020-09-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
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更新日期:2012-07-01 00:00:00
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journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Review of 158 cases of renal traumatism attended ar the Urology Service of "La Fe" Hospital from 1984 to 1995. We analyze the indications of radiological study of the polytraumatized patient, the different classifications of renal traumatism and the changes produced in the diagnosis protocol, after substituting urogra...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::Presentation of one case of metastatic renal adenocarcinoma with iliac bone and soft parts involvement which presented as a lumbosciatic picture. A comment is made on the different diseases which can result in painful lumbar syndrome, reaching an agreement on the need to conduct more extensive studies given the lack o...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::The present job reviews the etiology, clinical presentation, diagnostic and treatment of interstitial cystitis. An exhaustive revision is made of all the possibilities of pharmacological treatment with a special mention to the two major drugs: dimethylsulfoxide and pentosampolysulphate. A critical judgement of existin...
journal_title:Actas urologicas espanolas
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:
更新日期:1990-05-01 00:00:00
abstract:CONTEXT:High-dose rate brachytherapy (HDR-BT) is an increasingly popular treatment for patients with localised prostate cancer (PC). OBJECTIVE:To assess the safety and efficacy of HDR-BT as monotherapy in PC. ACQUISITION OF EVIDENCE:A systematic literature review was conducted through searches on MEDLINE (PubMed), Co...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/j.acuro.2016.06.001
更新日期:2017-03-01 00:00:00
abstract::We present a case of seminal vesicle cyst in a fertile patient. Sporadically appearing hemospermia was the only symptom. We single out thiss pathology and the clinical procedure of this case as being uncommon. Transabdominal echography revealed the presence of the cyst. The T.A.C. did not offer further data. The Defer...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1989-07-01 00:00:00