New estimates of herpes simplex virus type 2 seroprevalence in England: 'high' but stable seroprevalence over the last decade.

Abstract:

OBJECTIVES:There have been few recent population-based herpes simplex virus type 2 (HSV-2) seroprevalence studies in England, but reports from the United States have indicated a 30% rise in HSV-2 seroprevalence between 1976 and 1994. This study aimed to ascertain trends in HSV-2 infection in England between 1991 and 2000. STUDY DESIGN:Anonymized serum residues collected through public health laboratories across England from individuals aged 16 to 64 years seeking health care through the National Health Service in 1991 (n = 2259) and 2000 (n = 3646) were tested for anti-HSV-2 IgG using the HerpeSelect 2 enzyme-linked immunosorbent assay IgG (Focus). RESULTS:In 9 sites across England, the age- and sex-standardized HSV-2 seroprevalence was 9.7% (95% confidence interval, 8.4-11.0%). Data from 4 sites common to both study years indicated no change in HSV-2 seroprevalence between 1991 and 2000. CONCLUSIONS:After adjustment for age, sex, and geographic location, there was no evidence of a change in seroprevalence between 1991 and 2000.

journal_name

Sex Transm Dis

authors

Morris-Cunnington M,Brown D,Pimenta J,Robinson NJ,Miller E

doi

10.1097/01.olq.0000118081.54177.95

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

243-6

issue

4

eissn

0148-5717

issn

1537-4521

pii

00007435-200404000-00010

journal_volume

31

pub_type

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