Abstract:
BACKGROUND:The diagnosis of bacterial vaginosis (BV) is often made according to Nugent's classification, a scoring system based on bacterial counting of Gram stained slides of vaginal secretion. However as the image area of the microscope field will influence the number of morphotypes seen there is a need to standardise the area. METHODS:A graph intended for recalculation of number of bacterial morphotypes seen by the observer using 1000 x magnification from various microscope set-ups was constructed and applied to data sets typical for scoring BV. The graph was used in recalculation of Nugent scores, which were also compared with the Ison/Hay scores to evaluate the consequences for the diagnosis of BV. RESULTS:The observed image area differed by 300% among the investigated microscope set-ups. In two different data sets, one treatment study and one screening study, a considerable change in the number of women classified as intermediate was seen when the graph was used to standardise the image area. The recalculated numbers were also compared to the Ison/Hay classification. Weighted kappa indexes between the different methods were 0.84, 0.88, and 0.90, indicating that the methods are comparable. CONCLUSION:Because of the considerable differences among image areas covered by different microscope set-ups used in Nugent and Ison/Hay scoring, there is a need to standardise the area in order to reach comparable scores reflecting the diagnosis of BV in different laboratories. The differences in the intermediate group will have a considerable effect on the results from both treatment and prevalence studies, even though the kappa indexes indicate very good agreement between the methods used.
journal_name
Sex Transm Infectjournal_title
Sexually transmitted infectionsauthors
Larsson PG,Carlsson B,Fåhraeus L,Jakobsson T,Forsum Udoi
10.1136/sti.2003.006106subject
Has Abstractpub_date
2004-02-01 00:00:00pages
63-7issue
1eissn
1368-4973issn
1472-3263journal_volume
80pub_type
杂志文章abstract:OBJECTIVES:Uptake of cervical screening among women aged 50-64 years is declining. Not feeling at risk because of current sexual behaviour is a reason some older women give for not being screened. We hypothesised that explaining the long interval between acquiring human papillomavirus (HPV) and developing cervical canc...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2019-054120
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:To explore the feasibility and acceptability of self-sampling for oropharyngeal and rectal specimens to screen for sexually transmitted infections (STIs) among men who have sex with men (MSM). Participant's willingness to self-sample at home was also explored. METHODS:Participants of a study to evaluate the...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2008.032193
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To assess STD management in primary healthcare facilities where STD clinics and syndromic management guidelines had been introduced. METHODS:In 26 health facilities in selected sites, we observed management of all STD patients presenting in the adult general or STD clinic. We assessed the referral system by ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.1.e2
更新日期:2002-02-01 00:00:00
abstract::In industrialised countries, a rapid epidemic phase of HIV transmission has largely given way to more moderated endemic transmission. The dynamics of endemic transmission may differ substantially from those generating epidemic spread. We hypothesise that three elements play an important role in maintaining endemicity ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.2006.017269
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND RATIONALE:The availability of urine based testing for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) provides a unique opportunity to screen for these pathogens outside traditional clinical settings. The researchers investigated the feasibility of street based CT/GC screening in the context of...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.5.357
更新日期:2002-10-01 00:00:00
abstract::Despite having the highest prevalence of any sexually transmitted infection (STI) globally, there is a dearth of data describing Trichomonas vaginalis (TV) incidence and prevalence in the general population. The lack of basic epidemiological data is an obstacle to addressing the epidemic. Once considered a nuisance in...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sextrans-2013-051075
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Considerable HIV transmission occurs among injection drug users (IDUs) in Pakistan and recently the HIV prevalence has been increasing among male (MSW), hijra (transgender; HSW) and female (FSW) sex workers. We describe past and estimate future patterns of HIV emergence among these populations in several cit...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2012-050872
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Australia has provided free quadrivalent human papillomavirus (HPV) vaccines to school girls since mid-2007 and a catch-up programme in the community to women aged up to 26 years in 2007-2009. We describe the temporal trend of genital warts in different populations in Melbourne. METHODS:We analysed the prop...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2014-051813
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:A community level randomised controlled trial of a Community Popular Opinion Leader (C-POL) intervention to reduce bacterial and viral sexually transmitted infections (STIs) and unprotected extramarital sex was carried out over 2 years in five countries. The main study results did not find significant interv...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/sti.2010.046243
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:To examine outcomes of a peer-led, community-based intervention providing rapid HIV testing and case management for linkage to care for untested men who have sex with men (MSM) in China. METHODS:Rapid HIV testing was performed by trained peer volunteers of a community-based organisation (CBO) in three citie...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sextrans-2013-051397
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:Qualitative research suggests that young women's relationships with the biological fathers of their children (BFRs), known colloquially as 'baby daddy' relationships, enable risk for pregnancy and STI/HIV. Our study compared partner characteristics and sexual risk within dyads based on BFR, among a sample of...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052157
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To determine whether Mycoplasma genitalium is associated with balanitis and/or posthitis in a previous study of the role of M genitalium in men with acute non-gonococcal urethritis (NGU). METHODS:In a previous study of men with acute NGU, the existence of balanitis and/or posthitis was recorded. Chlamydia tr...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.044487
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Recently, the world has experienced a rapidly escalating outbreak of infectious syphilis primarily affecting men who have sex with men (MSM); many are taking highly active antiretroviral therapy (HAART) for HIV-1 infection. The prevailing hypothesis is that HAART availability and effectiveness...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sextrans-2016-052870
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:In the absence of a single nucleic acid amplification test (NAAT) that is both highly specific and sensitive for gonorrhoea, many have put forward the 16S-based assay as a confirmatory test for Neisseria gonorrhoeae. This study was undertaken to evaluate the performance of PCR based on 16S ribosomal gene in ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2009.041418
更新日期:2010-11-01 00:00:00
abstract::We present the case of a 26 year old HIV positive homosexual man who was managed for suspected Crohn's disease for over 1 year before lymphogranuloma venereum (LGV) was clinically diagnosed. He had presented with constipation, secondary to acute haemorrhagic proctitis, and subsequently had two chlamydia negative recta...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2005.016667
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:To compare the characteristics of a self-selected, convenience sample of men who have sex with men (MSM) recruited through the internet with MSM drawn from a national probability survey in Great Britain. METHODS:The internet sample (n = 2065) was recruited through two popular websites for homosexual men in ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2006.023283
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:To ascertain the prevalence of Trichomonas vaginalis and investigate associations between trichomoniasis, endometritis and sequelae among women with pelvic inflammatory disease (PID). METHODS:We assessed the prevalence of trichomoniasis identified via wet mount and its association with histologically confirm...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2019-054079
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:The authors estimate the prevalence of HIV, syphilis, hepatitis B virus (HBV) and herpes simplex virus type-2 (HSV-2) infection and correlates of HBV and HSV-2 infection among truck drivers crossing the southern Brazilian border at Foz do Iguaçu. METHODS:Between October 2003 and March 2005, 1945 truck drive...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2011-050186
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:In countries where STI/HIV prevalence data and behavioural data are scarce UNAIDS second generation HIV surveillance guidelines recommend measuring STI/HIV prevalence and risk behaviours in vulnerable populations but do not recommend conducting these surveys concurrently because of concerns about participati...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.3.187
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:To describe the seroepidemiology of herpes simplex virus (HSV) types 1 and 2 in the general populations of eight European countries to better understand recent reported changes in disease epidemiology. METHODS:Belgium, Bulgaria, Czech Republic, England and Wales, Finland, Germany, Netherlands, and Slovenia ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2003.005850
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:The INSIGHT case-control study confirmed that HIV serodiscordant unprotected anal intercourse (SdUAI) remains the primary risk factor for HIV infection in gay men in England. This paper uses qualitative follow-up data to examine the contexts of SdUAI and other risk factors among the case-control study partic...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2008.031468
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The polymer conjugate enhanced enzyme immunoassay (IDEIA) and Cobas Amplicor polymerase chain reaction Chlamydia trachomatis (CT) (Amplicor PCR) are two commonly used assays for the diagnosis of CT infection. The performance of these assays was compared for the diagnosis of genital CT infection am...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2005.015362
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:To investigate the risk factors for infection and the outcome of pregnancy in women diagnosed with syphilis using a molecular approach. METHODS:Case-control study of pregnant women admitted to a maternity ward, with the cases classified as early or latent maternal syphilis, based on clinical-serological dia...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2012-050552
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:Behavioural interventions have been shown to reduce sexual behaviours associated with increased risk of sexually transmitted infections in young people (<25 years) and men who have sex with men (MSM) internationally, but evidence from England is limited. We aimed to explore service provider and user experienc...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2018-053903
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:To undertake the first comprehensive analysis of the incidence of three curable sexually transmissible infections (STIs) within remote Australian Aboriginal populations and provide a basis for developing new control initiatives. METHODS:We obtained all results for Chlamydia trachomatis (CT), Neisseria gonor...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2014-051617
更新日期:2015-03-01 00:00:00
abstract::Sexually transmitted diseases (STDs) may be transmitted during sexual assault. In children, the isolation of a sexually transmitted organism may be the first indication that abuse has occurred. Although the presence of a sexually transmissible agent from a child beyond the neonatal period is suggestive of sexual abuse...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.74.3.167
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:This study examines violence experienced in work and personal contexts and relation to HIV risk factors in these contexts among female sex workers (FSW) in Andhra Pradesh, India. METHODS:FSW at least 18 years of age (n=2335) were recruited through three rounds of respondent-driven sampling between 2006 and ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052162
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:Reinfection after treatment for Chlamydia trachomatis or Neisseria gonorrhoeae reduces the effect of control interventions. We explored the impact of delays in treatment of current partners on the expected probability of reinfection of index cases using a mathematical model. METHODS:We used previously repor...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2013-051279
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:A new molecular test for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) (GeneXpert CT/NG) has been demonstrated to be as accurate as conventional nucleic acid amplification tests (NAAT), but performance has not been evaluated in routine primary care, performed at the point of care by clinicians. W...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,随机对照试验
doi:10.1136/sextrans-2017-053443
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:We undertook a prospective evaluation of the Qualpro Syphicheck-WB rapid syphilis test to measure its diagnostic performance and utility as a point-of-care (POC) screening test among female sex workers (FSWs) in Bangalore, India. METHODS:From August 2008 to May 2009, FSWs without a laboratory-confirmed hist...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2009.038778
更新日期:2010-06-01 00:00:00