Are proton pump inhibitors indicated for the treatment of gastroesophageal reflux in infants and children?

abstract：:The contrasting effects of natural versus cow's milk formula (CMF) on upper gastrointestinal development in the newborn were studied. The passive intestinal permeability of neonatal human infants and guinea pigs was measured using the nonmetabolisable markers lactulose and mannitol. Mucosal morphology was examined in ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Weaver LT,Laker MF,Nelson R,Lucas A

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to perform a retrospective observational review of the present management and outcome of cholestatic pruritus in children with Alagille syndrome (AGS) at King's College Hospital and to use results to inform appropriate guidelines. METHODS:A retrospective review of 62 patients diag...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kronsten V,Fitzpatrick E,Baker A

更新日期：2013-08-01 00:00:00

abstract：:The Pancreas Committee of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition aims to promote awareness of pediatric pancreatic diseases, support clinical and basic science research in the field, educate pediatric gastroenterologists, and advocate on behalf of pediatric patients with pa...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Grover AS,Freeman AJ,Abu-El-Haija M,Eisses JF,Gardner TB,Liu QY,Lowe ME,Nathan JD,Palermo TM,Singh VK,Trout AT,Uc A,Husain SZ,Morinville VD

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate erosive esophagitis healing and symptom improvement with once-daily esomeprazole in children ages 12 to 36 months with endoscopically or histologically proven gastroesophageal reflux disease (GERD). PATIENTS AND METHODS:Data from children ages 12 to 36 months were includ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tolia V,Gilger MA,Barker PN,Illueca M

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:Esophageal strictures in children are serious and require specialized care. Peptic stricture is most common in our context, whereas caustic and congenital strictures are rare. The present study reports our experience in esophageal endoscopic dilation while specifying the causes of esophageal strictures as wel...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lakhdar-Idrissi M,Khabbache K,Hida M

更新日期：2012-06-01 00:00:00

abstract：:The serum levels of five acute phase proteins (APP) were measured in 18 children with Crohn's Disease (CD) or ulcerative colitis (UC) and in two control groups. The levels of C-reactive protein, alpha 1-acid glycoprotein, alpha 1-antitrypsin, C9, and Factor B were significantly raised in patients with CD and UC with g...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Campbell CA,Walker-Smith JA,Hindocha P,Adinolfi M

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Premature infants receiving alimentation with cow milk-based formulas run a considerably high risk of incipient late metabolic acidosis, an early stage developing of manifest late metabolic acidosis. Is bone metabolism involved in pathophysiologic mechanisms characterizing this early stage of retention acido...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kalhoff H,Diekmann L,Rudloff S,Manz F

更新日期：2001-11-01 00:00:00

abstract：:To characterize the mechanisms leading to dietary evoked increases of lactase and sucrase activities by carbohydrates, we performed a quantitative comparison of the effects of lactose and sucrose on the corresponding disaccharidases in the jejunum of 2-month-old rats. For 7-10 days the rats were fed a low-starch (5 ca...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Goda T,Bustamante S,Koldovský

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Children with Crohn disease (CD) often undergo cross-sectional imaging during clinical evaluation. Magnetic resonance enterography (MRE) is becoming the preferred radiologic assessment due to the lack of radiation exposure; however, there are few data in children with CD comparing MRE with obje...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sauer CG,Middleton JP,Alazraki A,Udayasankar UK,Kalb B,Applegate KE,Martin DR,Kugathasan S

更新日期：2012-08-01 00:00:00

abstract：:The perianal complications of Crohn's disease (CD) seen in children and adolescents include skin tags, anal fissures, fistulae, and abscesses. While these lesions are often chronic and variably responsive to medical therapy, only rarely are they severely destructive. In this report, we characterize the frequency, seve...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Markowitz J,Grancher K,Rosa J,Simpser E,Aiges H,Daum F

更新日期：1995-08-01 00:00:00

abstract：:The effect of a lipid emulsion containing long-chain triglycerides (LCT) and supplemented with L-carnitine on plasma lipids and bilirubin in premature neonates on total parenteral nutrition was compared to that of lipid emulsions containing either LCT or a mixture of LCT and medium-chain triglycerides (MCT). In a doub...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rubin M,Naor N,Sirota L,Moser A,Pakula R,Harell D,Sulkes J,Davidson S,Lichtenberg D

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVES:Osteoporosis is the most common manifestation of untreated celiac disease (CD). Bone quantitative ultrasound (QUS) has recently emerged as a new modality for bone status assessment. We evaluated bone status in children with CD using dual-energy x-ray absorptiometry and quantitative ultrasound. METHODS:This ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hartman C,Hino B,Lerner A,Eshach-Adiv O,Berkowitz D,Shaoul R,Pacht A,Rozenthal E,Tamir A,Shamaly H,Shamir R

更新日期：2004-11-01 00:00:00

abstract：:To further evaluate the nature of malnutrition, define at-risk groups, and confirm the efficacy of nutritional supplementation on body composition in cystic fibrosis (CF), we have conducted longitudinal and cross-sectional studies of total body potassium (TBK) in 161 unselected CF subjects aged 1 month to 17 years. TB...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shepherd RW,Holt TL,Greer R,Cleghorn GJ,Thomas BJ

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:Tumor necrosis factor (TNF)-alpha plays a role in the inflammatory process in Crohn disease, a disease with an apparent polygenic basis. We investigated whether polymorphisms in multiple genes involved in the lipopolysaccharide-TNF inflammatory pathway are independently associated with Crohn disease in the Je...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Silbermintz A,Levine J,Weinstein T,Silver J

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:In developed countries, small bowel histology in coeliac disease is a spectrum, ranging from normal with increased intraepithelial lymphocytes to the classic flat mucosa. In developing countries, mild to moderate enteropathies in children with chronic diarrhea and growth failure are assumed to be caused by t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bhatnagar S,Gupta SD,Mathur M,Phillips AD,Kumar R,Knutton S,Unsworth DJ,Lock RJ,Natchu UC,Mukhopadhyaya S,Saini S,Bhan MK

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:Differentiation of Crohn disease (CD) from ulcerative colitis (UC) is challenging when inflammation is predominantly colonic. The paediatric inflammatory bowel disease (PIBD) classes algorithm was developed to bring consistency to labelling, but used physician-assigned diagnosis as the criterion standard. We...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Dhaliwal J,Siddiqui I,Muir J,Rinawi F,Church PC,Walters TD,Griffiths AM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The causal association between Helicobacter pylori (H. pylori) colonization of the gastric mucosa and gastritis is now well established. Histologic examination of endoscopic biopsy specimens has long been regarded as the gold standard for diagnosis. However, the changes can be focal in nature and presence of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Delvin EE,Brazier JL,Deslandres C,Alvarez F,Russo P,Seidman E

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:There is an inverse relationship between gestational age, birth weight and the time of first neonatal bowel movement. The authors hypothesized that delayed passage of meconium might result from a delayed maturation of the recto-anal inhibitory reflex (RAIR) in premature infants. OBJECTIVE:To evaluate whethe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： de Lorijn F,Voskuijl WP,Omari TI,Kok JH,Taminiau JA,Benninga MA

更新日期：2005-04-01 00:00:00

abstract：:The general goals of treatment of cyclic vomiting syndrome (CVS) are: interruption of established episodes, amelioration of symptoms in patients whose episodes cannot be interrupted, aborting episodes during prodromal symptoms, prophylaxis to abolish or lessen the frequency of episodes, and recovery. Complications of ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fleisher DR

更新日期：1995-01-01 00:00:00

abstract：:Milk was obtained on postpartum days 2-3 (colostrum) and days 7, 21, 42, and 84 from mothers of 18 very premature (VPT, 26-30 weeks gestational age), 28 premature (PT, 31-36 weeks), and 6 term (T, 37-40 weeks) infants. Lipids were extracted in chloroform-methanol and analyzed by thin-layer (TLC) and gas liquid chromat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bitman J,Wood DL,Mehta NR,Hamosh P,Hamosh M

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:A sharp increase in paediatric (younger than 16 years) inflammatory bowel disease (IBD) incidence was observed in northern Stockholm County, Sweden, in 1990-2001. The increasing incidence was primarily explained by a rising incidence of Crohn disease (CD). Here, we present an update on the trends in incidenc...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Malmborg P,Grahnquist L,Lindholm J,Montgomery S,Hildebrand H

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Small for gestational age (SGA) infants are more susceptible to infectious morbidity and growth faltering compared to their appropriate for gestational age (AGA) counterparts. Zinc supplementation of SGA infants may be beneficial but the underlying susceptibility to zinc deficiency of SGA infants has not bee...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ariff S,Krebs NF,Westcott JE,Hambidge M,Miller LV,Rizvi A,Soofi SB,Bhutta ZA

更新日期：2018-03-01 00:00:00

abstract：:Visceral hypersensitivity and abnormal coping are common in children with functional abdominal pain disorders (FAPDs). Thus, it would be expected that children with visceral hypersensitivity would report more pain if their gut is acutely inflamed. The aim of the study was to compare clinical symptoms and somatization ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Saps M,Mintjens S,Pusatcioglu CK,Cohen DM,Sternberg P

更新日期：2017-08-01 00:00:00

abstract：:To determine the frequency of gastric acid hypersecretion in infants with chronic malabsorption due to short bowel syndrome, acid secretory function was determined in 23 infants with malabsorption 2-22 months following small bowel resection and in a control group of 14 chronically ill, age- and weight-matched infants ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hyman PE,Everett SL,Harada T

更新日期：1986-03-01 00:00:00

abstract：:Lactoferrin is an iron-binding protein present in high concentrations in human milk. The efficacy of supplementing iron bound to lactoferrin to iron-deficient and iron-sufficient young mice was evaluated in comparison with supplementation of iron as iron chloride. Mice fed a nonsupplemented milk diet (approximately 1 ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fransson GB,Keen CL,Lönnerdal B

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVES:Environmental enteropathy (EE) is likely associated with growth retardation in children, but the association between EE and length velocity z score (LVZ) has not been investigated. The objective of the study was to assess associations between fecal markers for intestinal inflammation and LVZ and whether thes...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Morseth MS,Henjum S,Schwinger C,Strand TA,Shrestha SK,Shrestha B,Chandyo RK,Ulak M,Torheim LE

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to use the breath ethane test to determine if either maternal cigarette smoking, formula, and/or deficiency of the antioxidant nutrients vitamins A and E was associated with oxidant stress in newborn infants. The rationale for this study was: (1) our observation that cigarette s...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Schwarz KB,Cox JM,Sharma S,Clement L,Witter F,Abbey H,Sehnert SS,Risby TH

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Selected infants with short bowel syndrome (SBS) and progressive intestinal failure associated liver disease (IFALD) may benefit from isolated liver transplantation (iLTx). The aim of the study is to identify risk factors for unfavourable outcome in iLTx. PATIENTS AND METHODS:A retrospective review of medica...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Dell-Olio D,Beath SV,de Ville de Goyet J,Clarke S,Davies P,Lloyd C,Protheroe S,Millar AJ,Kelly DA,Gupte GL

更新日期：2009-03-01 00:00:00

abstract：:The clinical expression of allergic disease is the consequence of a series of complex gene-environment interactions that occur at the materno-fetal interface and throughout infancy, leading to persistence of the Th2 immune response. It has been proposed that atopic eczema is the cutaneous manifestation of a systemic d...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cox HE

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:To assess and compare efficacy of two micronutrient sprinkle supplementation on growth, anemia, and iron deficiency in Cambodian infants. METHODS:A total of 204 infants aged 6 months and living in Kompong Chhnang Province, Cambodia were randomly assigned to receive daily supplements of either iron (12.5 mg)...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Giovannini M,Sala D,Usuelli M,Livio L,Francescato G,Braga M,Radaelli G,Riva E

更新日期：2006-03-01 00:00:00