Regional differences in the number and type of myenteric neurons in the descending colon of rats.

Abstract:

:The purpose of this study was to analyze the neuronal density of the myenteric plexus of the intermediate and antimesocolic regions of the descending colon of rats. Whole-mounts were stained with three different techniques of neuronal evidenciation. Through counts of the number of neurons in an area of 6.64 mm under light microscopy, we found 1,271 +/- 227.54 neurons with Giemsa in the intermediate region and 1,234 +/- 225.92 neurons in the antimesocolic region; with the NADH-diaphorase technique we found 530 +/- 92.97 neurons in the intermediate region and 539 +/- 146.72 neurons in the antimesocolic region; and through the NADPH-diaphorase histochemistry, we found 417 +/- 34.42 neurons in the intermediate region and 547 +/- 84.01 neurons in the antimesocolic region. We conclude that there is a variation in the density of NADPH-diaphorase positive neurons in the intestinal circumference; that the NADH-diaphorase positive neuronal subpopulation represented 42.7% of that stained with Giemsa; and that the NADPH-diaphorase positive neurons represented 37.8% of the whole myenteric population.

journal_name

Arq Neuropsiquiatr

authors

Araújo EJ,Sant'Ana Dde M,Molinari SL,de Miranda Neto MH

doi

10.1590/s0004-282x2003000200011

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

220-5

issue

2A

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2003000200011

journal_volume

61

pub_type

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