Familial bilateral papillary cystadenoma of the epididymis: report of three cases in siblings.

abstract：BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...

journal_title：Cancer

authors： Jones GW,Rosenthal D,Wilson LD

更新日期：1999-05-01 00:00:00

abstract：:Studies of chemotherapy in advanced or recurrent gynecologic cancer have focussed on ovarian, cervical, and endometrial carcinoma. For celomic epithelial carcinomas of the ovary, a large number of cytotoxic agents have been shown to be active. Dramatic improvement in frequency of response with lesser improvement in su...

journal_title：Cancer

authors： Thigpen T,Vance R,Lambuth B,Balducci L,Khansur T,Blessing J,McGehee R

更新日期：1987-10-15 00:00:00

abstract：:Several reports describe the association of hyperlymphocytosis with neutropenia. This syndrome, named lymphoproliferative disease, is characterized by a chronic indolent clinical course, bone marrow lymphocyte infiltration, and granulopenia of central origin. The proliferating lymphocytes share large granular lymphocy...

journal_title：Cancer

authors： Le Deist F,de Saint Basile G,Coulombel L,Breton-Gorius J,Maier-Redelsperger M,Beljorde K,Bremard C,Griscelli C

更新日期：1991-05-15 00:00:00

abstract：:Five cases of squamous cell carcinoma of the cervix associated with widespread squamous cell carcinoma in situ of the endometrial surface are reported. In one case, carcinoma in situ was also found in one fallopian tube in continuity with the cervicoendometrial lesion. A survey of the literature reveals only 20 cases ...

journal_title：Cancer

authors： Kanbour AI,Stock RJ

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that the prognosis in patients with extremity soft-tissue sarcomas (ESTS) with isolated lymph node (LN) metastases (stage IV) is comparable to that of patients with high-risk ESTS without metastases (stage III). This study was performed to determine the outcomes of patients wh...

journal_title：Cancer

authors： Al-Refaie WB,Andtbacka RH,Ensor J,Pisters PW,Ellis TL,Shrout A,Hunt KK,Cormier JN,Pollock RE,Feig BW

更新日期：2008-04-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：:The presence of receptors for estrogen, glucocorticoid and progesterone was determined in the cytosol of two breast angiosarcomas. Estrogen and glucocorticoid receptors were present in both of them. Progesterone receptors were present in one of the two tumors assayed. Occupied nuclear estrogen receptors have been foun...

journal_title：Cancer

authors： Brentani MM,Pacheco MM,Oshima CT,Nagai MA,Lemos LB,Góes JC

更新日期：1983-06-01 00:00:00

abstract：:This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented. ...

journal_title：Cancer

authors： Esseltine DW,Vekemans M,Seemayer T,Reece E,Gordon J,Whitehead VM

更新日期：1982-08-01 00:00:00

abstract：:A prospective randomized trial by CALGB examined the relative value of four chemotherapy regimens in 537 patients with stage III B and IV Hodgkin's disease. A new combination BOPP, derived by substitution of BCNU for nitrogen mustard in the MOPP regimen, was compared to MOPP and to two 3-drug regimens, derived by remo...

journal_title：Cancer

authors： Nissen NI,Pajak TF,Glidewell O,Pedersen-Bjergaard J,Stutzman L,Falkson G,Cuttner J,Blom J,Leone L,Sawitsky A,Coleman M,Haurani F,Spurr CL,Harley JB,Seligman B,Cornell C Jr,Henry P,Senn HJ,Brunner K,Martz G,Maurice

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Patients with Stage I Grade 1 endometrial carcinoma have an excellent prognosis and a 10-year survival rate of more than 90%. In every clinical series, however, a few patients in this group have recurrence and die of their disease. METHODS:The authors reviewed 80 patients with Stage I Grade 1 endometrial ca...

journal_title：Cancer

authors： Tornos C,Silva EG,el-Naggar A,Burke TW

更新日期：1992-08-15 00:00:00

abstract：BACKGROUND:Even when they are analogous in microscopic and macroscopic appearance, tumors vary in their response rates to radiotherapy. Cell culture and xenograft experiments with colorectal cell lines have demonstrated that wild-type p53 increases radiosensitivity. Hence, the authors investigated, in a well-defined po...

journal_title：Cancer

authors： Nehls O,Klump B,Holzmann K,Lammering G,Borchard F,Gruenagel HH,Gaco V,Gregor M,Porschen R

更新日期：1999-06-15 00:00:00

abstract：:The authors describe two cases of Fournier's gangrene complicating aggressive therapy for hematologic malignancies. Fournier's gangrene is a fulminant necrotizing fasciitis of the scrotum and penis, often with an infectious etiology. Only one prior case has been reported in a patient receiving aggressive chemotherapy ...

journal_title：Cancer

authors： Berg A,Armitage JO,Burns CP

更新日期：1986-06-15 00:00:00

abstract：BACKGROUND:The goal of the current study was to define the clinical features and outcome of recurrent osteosarcoma (OS) in children and young adults initially treated with contemporary chemotherapy. METHODS:The authors reviewed the clinical features, therapy, and outcome for 59 patients from the Mayo Clinic (Rochester...

journal_title：Cancer

authors： Hawkins DS,Arndt CA

更新日期：2003-12-01 00:00:00

abstract：:The use of prostate-specific antigen (PSA) as a screening test remains controversial. There have been several attempts to refine PSA measurements to improve its predictive value. These modifications, including PSA density, PSA kinetics, and the measurement of PSA isoforms, have met with limited success. Therefore, com...

journal_title：Cancer

authors： Herman MP,Dorsey P,John M,Patel N,Leung R,Tewari A

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) develops through the alteration of several critical pathways. This study was aimed at evaluating the influence of critical pathways on survival outcomes for patients with CRC. METHODS:Targeted next-generation sequencing of 40 genes included in the 5 critical pathways of CRC (WNT, P53...

journal_title：Cancer

authors： Lee DW,Han SW,Cha Y,Bae JM,Kim HP,Lyu J,Han H,Kim H,Jang H,Bang D,Huh I,Park T,Won JK,Jeong SY,Park KJ,Kang GH,Kim TY

更新日期：2017-09-15 00:00:00

abstract：:Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Comb...

journal_title：Cancer

authors： Richards F 2nd,Pajak TL,Cooper MR,Spurr CL

更新日期：1975-11-01 00:00:00

abstract：:Forty-three patients with widely metastatic melanoma were studied. Visceral metastases were present in 79% of the patient group, including five patients with brain metastases. No patients were excluded because of "early death," etc., from analysis. All 43 patients received 24-hour DTIC infusions. Dosages for individua...

journal_title：Cancer

authors： Thatcher N,Anderson H,James R,Davenport P,Craig P

更新日期：1986-06-01 00:00:00

abstract：:Despite relatively high response rates to chemotherapy for ovarian carcinoma, most patients eventually will have progressive disease that will require additional therapy. Most efforts to study such second-line or "salvage" chemotherapy have been single-arm trials of small numbers of patients, which report widely varia...

journal_title：Cancer

authors： Thigpen JT,Vance RB,Khansur T

更新日期：1993-02-15 00:00:00

abstract：:Six patients with Hodgkin's disease who developed idiopathic thrombocytopenic purpura (ITP) are presented. In contrast to prior cases reported in the literature, none of these patients developed recurrent Hodgkin's disease at the time of or subsequent to their thrombocytopenia, with follow-up data available up to 10 y...

journal_title：Cancer

authors： Cohen JR

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Colonoscopic screening has increased detection of malignant colonic polyps (MPs). The goal of this study was to analyze trends and patterns in the surgical treatment of MPs and to assess outcomes as measured by lymph node retrieval and patient survival. METHODS:The Surveillance, Epidemiology, and End Result...

journal_title：Cancer

authors： Wasif N,Etzioni D,Maggard MA,Tomlinson JS,Ko CY

更新日期：2011-03-01 00:00:00

abstract：:Reported is the case of a 24-year-old white man with inoperable giant cell carcinoma of the thyroid who achieved tumor regression following therapy with bleomycin, Adriamycin and cisplatinum. After 2 courses of chemotherapy, the tumor was deemed operable, and the patient underwent total thyroidectomy followed by radia...

journal_title：Cancer

authors： Spanos GA,WolK D,Desner MR,Khan A,Platt N,Khafif RA,Cortes EP

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Health systems in Sub-Saharan Africa are not prepared for the rapid rise in cancer rates projected in the region over the next decades. More must be understood about the current state of cancer care in this region to target improvement efforts. Yaounde General Hospital (YGH) currently is the only site in Cam...

journal_title：Cancer

authors： Price AJ,Ndom P,Atenguena E,Mambou Nouemssi JP,Ryder RW

更新日期：2012-07-15 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related peptide (PTHrP) is a tumor-derived circulating factor that has been associated with hypercalcemia of malignancy. The role of PTHrP as a prognostic indicator remains unclear. Studies suggest that it may function as a growth factor; and, recently, the ability of PTHrP to induce cyto...

journal_title：Cancer

authors： Deans C,Wigmore S,Paterson-Brown S,Black J,Ross J,Fearon KC

更新日期：2005-05-01 00:00:00

abstract：:Eighteen patients with unresectable ductal adenocarcinoma of the pancreas received definitive, high-dose, small-volume radiation therapy. All patients had at least one laparotomy, at which time a biopsy was obtained, radio-opaque clips were placed to define the extent of the gross tumor, and usually some form of bypas...

journal_title：Cancer

authors： Dobelbower RR Jr,Borgelt BB,Suntharalingam N,Strubler KA

更新日期：1978-03-01 00:00:00

abstract：:As resources become increasingly scarce, oncology professionals and consumers of oncology services are increasingly engaging in advocacy efforts to achieve goals in cancer control. Effective advocacy includes both legislative and direct educational efforts. ...

journal_title：Cancer

authors： Berkman B,Stevenson E,Cravedi KG,Davis A,Lawrence W Jr,Mor V,Ostrander V,Rubenstein LJ,Speers M,Wilson K

更新日期：1991-12-01 00:00:00

abstract：:Light microscopic, immunocytochemical and ultrastructural studies were performed on chondrosarcomas which contained a second, noncartilagenous mesenchymal component. Attention was focused on the nonchondroid portion of each tumor in an attempt to elucidate the histogenesis of this mixed variant of chondrosarcoma. The ...

journal_title：Cancer

authors： Têtu B,Ordóñez NG,Ayala AG,Mackay B

更新日期：1986-07-15 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:9-Aminocamptothecin (9AC) and its parent compound, camptothecin, have shown outstanding preclinical activity against colorectal carcinoma. Irinotecan (CPT-11), another camptothecin derivative, has demonstrated clinical activity in patients with 5-fluorouracil (5-FU)-refractory colorectal carcinoma. METHODS:...

journal_title：Cancer

authors： Saltz LB,Kemeny NE,Tong W,Harrison J,Berkery R,Kelsen DP

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:The authors evaluated the two indicators of metastatic proclivity (namely, virulence [V; the rate of appearance of distant metastases] and metastagenicity [M; the ultimate likelihood of developing distant metastases]) of breast carcinoma in elderly women. The authors then compared these characteristics with ...

journal_title：Cancer

authors： Singh R,Hellman S,Heimann R

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxel. METHODS:Patients with Stage IIIB (pleural effusion) or ...

journal_title：Cancer

authors： Edelman MJ,Gandara DR,Lau DH,Lara P,Lauder IJ,Tracy D

更新日期：2001-07-01 00:00:00