Abstract:
:Cervical cancer is a preventable disease that is curable when it is detected early. For advanced-stage cancer, the prognosis is worse. Over the years, much progress has been made in radiation therapy and in chemotherapy, but it took three decades for the arrival of concurrent chemoradiation therapy, which significantly improved the survival among women with advanced cervical cancer. This fact underscores the need and the importance for continuing efforts in clinical research. While current standards of therapy are being fine-tuned as more information is being gathered, great strides are being made in the areas of molecular and cancer biology. Novel treatments for cervical cancer appear to be imminent in the near future.
journal_name
Obstet Gynecol Clin North Amjournal_title
Obstetrics and gynecology clinics of North Americaauthors
Im SS,Monk BJdoi
10.1016/s0889-8545(02)00024-4subject
Has Abstractpub_date
2002-12-01 00:00:00pages
659-72issue
4eissn
0889-8545issn
1558-0474pii
S0889-8545(02)00024-4journal_volume
29pub_type
杂志文章,评审abstract::Growing attention is being paid to obstetric quality of care as patients are pressing the health care system to measure and improve quality. There is also an increasing recognition of persistent racial and ethnic disparities prevalent in obstetric outcomes. Yet few studies have linked obstetric quality of care with ra...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2016.10.002
更新日期:2017-03-01 00:00:00
abstract::Recognizing the enormous impact that quality breast screening mammography can have on reducing breast cancer deaths, we need to determine when women's and physician's perceived restrictions for mammography examination impede the progress of its use for early cancer detection. A uniform system should emphasize valid co...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
abstract::The incidence of malignant melanoma is rising, and this may be the most frequently encountered malignancy during pregnancy. Because effective treatment of advanced or metastatic disease remains elusive, the key to adequate therapy is surveillance for early disease with prompt diagnostic work-up and treatment. Review o...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(05)70014-0
更新日期:1998-06-01 00:00:00
abstract::Puberty is the sequence of events that culminates in the ability to procreate. It is widely accepted that the onset of puberty in girls occurs on average at 8 years of age and that onset prior to 8 years of age is precocious puberty. As a result of the cross-sectional study by the American Association of Pediatrics, a...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(03)00025-1
更新日期:2003-06-01 00:00:00
abstract::A specific technique of advanced operative laparoscopy, known as videolaseroscopy, using the CO2 laser and videomonitor, is described. Operating room setup, anesthesia considerations, and specific applications to pelvic disease are elaborated. ...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-09-01 00:00:00
abstract::Although the advent of broad-spectrum antibiotics has markedly improved the maternal outcomes of pneumonia complicating pregnancy, pneumonia remains a significant condition that may complicate pregnancy. This article has reviewed the inherent physiologic respiratory changes that accompany pregnancy and the common caus...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(05)70217-5
更新日期:2001-09-01 00:00:00
abstract::Abnormal uterine bleeding occurs secondary to a wide variety of functional and structural abnormalities. Although there is clearly a place for surgery, medical therapy has enormous potential for most women, especially those with dysfunctional uterine bleeding. To provide women with appropriate options for therapy, the...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(00)80021-2
更新日期:2000-06-01 00:00:00
abstract::The study of multiple gestations in older mothers has been furthered by the analyses of large data sets published in recent years. These initial analyses are counterintuitive in that the obstetric and neonatal outcomes of the older mothers (>40 years) are better than those of their younger counterparts (aged 25-29). C...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2004.10.010
更新日期:2005-03-01 00:00:00
abstract::Chorionic villus sampling (CVS) has been used a successful and safe first-trimester prenatal diagnostic technique for over 12 years. Developed to avoid the medical and psychological complications of later prenatal diagnosis by amniocentesis, CVS rapidly has become a primary tool for the diagnosis of fetal cytogenetic,...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(05)70291-6
更新日期:1997-03-01 00:00:00
abstract::Access to the fetus as a true patient is a recent development in maternal-fetal medicine. We review the major invasive techniques currently available for establishing diagnoses and providing treatments to the fetus. These include fetoscopy, fetal blood sampling, fetal transfusions, and fetal shunts. Indications, techn...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00
abstract::Desire and arousal disorders are very common. These disorders can cause significant distress to a patient. A successful approach depends on an accurate diagnosis, which is dependent on history. Laboratory evaluation is usually not helpful, whereas psychosexual therapy is helpful in many cases. Although there is some e...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2006.10.004
更新日期:2006-12-01 00:00:00
abstract::As many as 50% of spontaneous preterm births are infection-associated. Intrauterine infection leads to a maternal and fetal inflammatory cascade, which produces uterine contractions and may also result in long-term adverse outcomes, such as cerebral palsy. This article addresses the prevalence, microbiology, and manag...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2005.03.001
更新日期:2005-09-01 00:00:00
abstract::The clinical integration of prenatal genetic technologies raises a series of important medical and ethical considerations for patients, families, health care providers, health care systems, and society. It is critical to recognize, understand, and address these issues in conjunction with the continued development of n...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2017.10.006
更新日期:2018-03-01 00:00:00
abstract::Except in special circumstances, therapeutic insemination with a husband's sample has a low success rate. Couples in whom oligozoospermia has been identified as the principal cause of infertility do not benefit from therapeutic insemination by husband. Because of this low success rate, intrauterine insemination to pro...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-12-01 00:00:00
abstract::The use of fetal blood sampling has been advocated widely to improve the specificity of fetal heart rate monitoring, but it remains a clinically unpopular procedure. This article considers its physiologic rationale and evidence base. It includes descriptions of the technique with suggestions for improved clinical inte...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(05)70104-2
更新日期:1999-12-01 00:00:00
abstract::Major advances in treatment for epithelial ovarian cancer have occurred over the last decade, giving hope to patients and families. Surgery remains a cornerstone of therapy. In early-stage epithelial ovarian cancer, a meticulous staging procedure should be performed to aid in determining patients who require appropria...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(05)70234-5
更新日期:2001-12-01 00:00:00
abstract::In summary, FDA-approved therapies for prevention and treatment of osteoporosis are all antiresorptive agents. There are no approved therapies at this time that stimulate bone formation, although one such agent (PTH) is awaiting approval. Screening perimenopausal women at risk should identify osteopenic women early in...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(02)00012-8
更新日期:2002-09-01 00:00:00
abstract::All the existing data show that combination estrogen/progestogen therapy is mandatory if any replacement therapy is to be given to the woman over age 40. Sufficient evidence has indicated that estrogen alone is inadequate; progestogen must be given to prevent endometrial hyperplasia, lower the risk of breast cancer, a...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-03-01 00:00:00
abstract::Hormone replacement therapy should be discussed with every postmenopausal woman and should be the first therapy offered to treat hot flashes owing to its high efficacy and other beneficial properties. Women who are ineligible for or uncomfortable with estrogen replacement therapy and who suffer from hot flashes that i...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1994-06-01 00:00:00
abstract::Lichen planus is an inflammatory mucocutaneous condition with a myriad of clinical manifestations. There are 3 forms of lichen planus that effect the vulva: papulosquamous, hypertrophic, and erosive. Erosive lichen planus can progress to vulvar scaring, vaginal stenosis, and squamous cell carcinoma; these long-term se...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2017.04.004
更新日期:2017-09-01 00:00:00
abstract::Implementing change is difficult; few people want to wade into this area because of the challenge. However, it is highly rewarding and does not have to be complicated. Success requires a clear understanding of health care context, patient safety, and behavioral psychology. To achieve its goal, this article is divided ...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2019.01.005
更新日期:2019-06-01 00:00:00
abstract::Sepsis is a leading cause of death in pregnancy and results in significant perinatal mortality. These deaths occur despite the younger age of pregnant patients, the low rate of comorbid conditions and the potential for effective interventions that should result in rapid resolution of illness. To date, no "evidence-bas...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2007.06.009
更新日期:2007-09-01 00:00:00
abstract::This article focuses on the clinical evaluation and management of women who have thrombophilia-related placental vascular complications, including fetal loss, pre-eclampsia, intrauterine fetal growth restriction, and placental abruption. All are major causes of maternal and fetal adverse outcomes. ...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2006.05.010
更新日期:2006-09-01 00:00:00
abstract::The hypothalamic-pituitary-adrenal axis is central to mammalian reproductive function, including conception, pregnancy maintenance, parturition, and breastfeeding. Pregnancy is associated with substantial physiologic changes within this endocrine axis to meet the demands of pregnancy, which include support of the fetu...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2004.08.003
更新日期:2004-12-01 00:00:00
abstract::Mobile apps and mobile health interventions have the potential to alter the landscape of medicine significantly, from how care is provided at the bedside to the ability to recruit patients and conduct medical research. Mobile apps have the potential to be used for prenatal care, postsurgical follow-ups, informing pati...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2020.02.008
更新日期:2020-06-01 00:00:00
abstract::The United States cesarean rate has risen from 5.5 per 100 deliveries in 1970 to 24.1 per 100 deliveries in 1986 according to the National Hospital Discharge Survey. Less than 10 per cent of mothers have a vaginal birth after a prior cesarean. Women spend an average of 5.0 days in the hospital for a cesarean delivery,...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::An understanding of cesarean delivery for nonreassuring fetal heart rate tracing is important for several reasons. This article describes the prevalence of cesarean for nonreassuring fetal heart rate tracing and risk factors, indicates what type of fetal heart rate tracing abnormalities prompts cesarean delivery, reit...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2005.01.003
更新日期:2005-06-01 00:00:00
abstract::Canavan disease is a severe leukodystrophy more common among Ashkenazi Jews. The enzyme defect, apartoacylase, has been identified, and the gene cloned. Only two mutations account for over 98% of all Jewish alleles with Canavan disease. The carrier frequency among healthy Jews is 1:37-58. Carrier detection and prenata...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8545(01)00003-1
更新日期:2002-06-01 00:00:00
abstract::As the health care system transforms to accommodate an increased need for primary care services and more patients, new models of health care delivery are needed that can provide quality health care services efficiently. An integrated collaborative practice of certified nurse-midwives, obstetrician-gynecologists, and p...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2012.05.009
更新日期:2012-09-01 00:00:00
abstract::This article discusses the role of ultrasound in assessing endometrial and uterine factors affecting the implantation of the embryo. Modern ultrasound equipment includes advanced Doppler and three-dimensional facilities that refine our understanding of factors that affect implantation such as endometrial blood flow. T...
journal_title:Obstetrics and gynecology clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.ogc.2019.08.002
更新日期:2019-12-01 00:00:00