Abstract:
OBJECTIVE:This study was designed to investigate the perceptual benefits and potential risks of implanting the Nucleus(R) multichannel auditory brainstem implant. DESIGN:Between September 1992 and October 1997 a total of 27 subjects received a Nucleus 20- or 21-channel Auditory Brainstem Implant (ABI). All subjects involved in the trial had bilateral acoustic tumour as a result of neurofibromatosis type 2 (NF2) resulting in complete dysfunction of the VIIIth nerve. The study used each subject as their own control without a preoperative baseline because residual hearing, if existing, was destroyed at surgery by tumour removal. A battery of speech tests was conducted to evaluate each patient's performance and communication abilities. Tests were conducted, where possible, in the auditory-only, visual-only, and auditory-visual conditions at 3 days postoperatively (baseline), at 3-mo intervals for the first year and every 12 mo thereafter. A subjective performance questionnaire was administered together with an extensive neurological examination at each test interval. RESULTS:27 subjects involved in this trial were successfully implanted with a Nucleus ABI. One subject died 2 days postoperatively due to a lung embolism unrelated to the device. Twenty-six subjects underwent device activation and all but one patient received auditory sensation at initial stimulation (96.2%). On average 8.6 (+/-4.2) of the available 21 electrodes were used in the patients' MAPs. Performance evaluation measures showed that the majority of users had access to auditory information such as environmental sound awareness together with stress and rhythm cues in speech that assist with lipreading. Although most subjects did not achieve any functional auditory-alone, open-set speech understanding, two subjects from this series (7.4%) did receive sufficient benefit to be able to use the ABI in conversation without lipreading. CONCLUSIONS:Although the medical risks and surgical complexity associated with ABI device implantation are far greater than those for a cochlear implant, the clinical results from this trial show that the Nucleus multichannel ABI is capable of providing a significant patient benefit over risk ratio for subjects suffering loss of hearing due to bilateral retrocochlear lesions.
journal_name
Ear Hearjournal_title
Ear and hearingauthors
Nevison B,Laszig R,Sollmann WP,Lenarz T,Sterkers O,Ramsden R,Fraysse B,Manrique M,Rask-Andersen H,Garcia-Ibanez E,Colletti V,von Wallenberg Edoi
10.1097/00003446-200206000-00002subject
Has Abstractpub_date
2002-06-01 00:00:00pages
170-83issue
3eissn
0196-0202issn
1538-4667journal_volume
23pub_type
临床试验,杂志文章相关文献
EAR AND HEARING文献大全abstract::The development of hand-held auditory screening devices has led to increased hearing screening by physicians. Ambient noise levels were assessed in examination rooms of 20 physician offices. Measurements provided Ln, Leq, Lmax, and octave band data for specialty types: pediatrics, internal medicine, family practice an...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199010000-00012
更新日期:1990-10-01 00:00:00
abstract::Full-term and preterm infants were evaluated with click-evoked and distortion-product otoacoustic emissions (CEOEs and DPOEs). The CEOEs and DPOEs recorded from each individual ear were analyzed by calculating the root-mean-square levels within half-octave bands. The fail criterion of the OE tests was that the half-oc...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199308000-00005
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVES:A postlingually implanted adult typically develops hearing with an intact auditory system, followed by periods of deafness (or near deafness) and adaptation to the implant. For an early implanted child whose brain is highly plastic, the auditory system matures with consistent input from a cochlear implant. I...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000463
更新日期:2018-01-01 00:00:00
abstract::The present study investigated the effects of intensity on hearing-impaired adults' performance on the Staggered Spondaic Word (SSW) test. Fifteen adults having mild-to-moderate cochlear hearing losses were administered the 40-item SSW test which was subdivided into four groups of ten items each, and presented at diff...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-198411000-00004
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVES:To determine whether (1) the auditory N1 component can be elicited to gaps in continuous narrowband noises, (2) psychophysical and electrophysiological gap thresholds (PGTs and EGTs) are similar to one another, and (3) EGTs are the same for all narrowband noise center frequencies. DESIGN:PGTs and EGTs were ...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0b013e3181b1354f
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:Binaural pitch fusion is the perceptual integration of stimuli that evoke different pitches between the ears into a single auditory image. Adults who use hearing aids (HAs) or cochlear implants (CIs) often experience abnormally broad binaural pitch fusion, such that sounds differing in pitch by as much as 3 ...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000874
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this investigation was to determine whether a predictable relationship existed between self-reported dizziness handicap and video Head Impulse Test (vHIT) results in a large sample of patients reporting to a dizziness clinic. Secondary objectives included describing the characteristics of the ...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000047
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:The study was designed to assess the effects of noise on the intelligibility of speech elements used in the Callsign Acquisition Test (CAT), developed by the U.S. Army Research Laboratory. The CAT consists of 126 test items, or callsigns, each of which is made up of a two-syllable word selected from the 18-it...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/01.aud.0000202289.32228.f6
更新日期:2006-04-01 00:00:00
abstract::Peripheral auditory sensitivity is documented over a 5-year period on 4 cases with otodental dysplasia. Age of onset is noted for the proband and indicates that onset of this progressive hearing loss occurs as early as the first decade. Findings suggest that the hearing loss plateaus by the fourth decade, resulting in...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-198103000-00007
更新日期:1981-03-01 00:00:00
abstract:OBJECTIVES:Hearing-impaired children are at risk for vestibular damage and delayed motor development. Two major causes of congenital hearing loss are cytomegalovirus (CMV) infection and connexin (Cx) 26 mutations. Comparison of the motor performance and vestibular function between these specific groups is still underex...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000364
更新日期:2017-01-01 00:00:00
abstract::In conventional auditory brain stem response (ABR) testing, the stimulus rate must be low enough that the responses do not overlap. By using stimulus patterns derived from the pseudorandom binary series known as maximum length sequences (MLSs), it is possible to stimulate at mean rates of hundreds of clicks per second...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199212000-00004
更新日期:1992-12-01 00:00:00
abstract:OBJECTIVE:To determine whether tympanic membrane (TM) electrodes induce behavioral pure-tone threshold shifts. DESIGN:Pure-tone thresholds (250 to 8000 Hz) were measured twice in test (n = 18) and control (n = 10) groups. TM electrodes were placed between first and second threshold measurements in the test group, wher...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000275
更新日期:2016-07-01 00:00:00
abstract::The test-retest reliability of the Hearing Handicap Inventory for Adults (HHIA) was assessed on a sample of 28 hearing-impaired adults. Reliability estimates were obtained to set the stage for using the HHIA as an outcome measure in aural rehabilitation. The test-retest reliability was quite high (r = 0.97) and the st...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199110000-00009
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:This study compares the musical perception of 17 adult recipients of the Nucleus cochlear implant using two different formant extraction processing strategies (F0F1F2 and MPEAK). DESIGN:Over a 12 mo period, participants were alternately switched between two strategies every 3 mo. Performance was evaluated us...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199706000-00008
更新日期:1997-06-01 00:00:00
abstract::The use of FM systems as primary amplification for children with severe and profound hearing loss is discussed. The FM advantage for improving speech perception and for reducing the detrimental effects of distance, noise, and reverberation is described. Both hypothetical and actual cases are used to demonstrate the FM...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199204000-00006
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVES:This study shows how population-based estimates of the prevalence of unilateral hearing loss (UHL) in children aged 6 to 19 yrs can differ considerably with various applications of commonly accepted case definitions. It also examines demographic variables and risk factors related to UHL. DESIGN:The Third Na...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0b013e3181bb69db
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this investigation was to determine whether the use of visual feedback of tonic electromyographic (EMG) activity, or the use of amplitude normalization techniques would reduce significantly the variability in cervical vestibular evoked myogenic potential (cVEMP) P13-N23 interaural amplitude as...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0b013e31827ad792
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:The main objective of this study is to determine whether chronic sound deprivation leads to poorer speech discrimination in humans. DESIGN:We reviewed the audiologic profile of 240 patients presenting normal and symmetrical bone conduction thresholds bilaterally, associated with either an acute or chronic u...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000787
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:In a cross-sectional study of human immunodeficiency virus (HIV)-infected adults, the authors showed lower distortion product otoacoustic emissions (DPOAEs) in HIV+ individuals compared with controls as well as findings consistent with a central auditory processing deficit in HIV+ adults on antiretroviral th...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000276
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this research was to measure the effects of reference interaural time and intensity differences on binaural performance in listeners with normal hearing and impaired hearing for a number of different binaural tests. Experiment 1 measures the dependence of binaural detection and discrimination p...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199508000-00001
更新日期:1995-08-01 00:00:00
abstract::In 430 individuals with adult onset hearing loss, relationships were explored between definitions of handicap based on a number of arithmetic formulas applied to audiometric data and definitions of handicap based on two self-report questionnaires (the Denver Scale of Communication Function and the Social Hearing Handi...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-198503000-00005
更新日期:1985-03-01 00:00:00
abstract::Averaged electrode voltages (AEVs) provide an objective measure of the output of the Nucleus multichannel cochlear implant device. AEVs are the peak-to-peak voltages of each electrode in the internal array and are recorded from electrodes placed on the scalp. This article summarizes average voltage data for 25 childre...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199404000-00007
更新日期:1994-04-01 00:00:00
abstract:OBJECTIVE:Recent studies indicate that high-frequency amplification may provide little benefit for listeners with moderate-to-severe high-frequency hearing loss, and may even reduce speech recognition. Moore and colleagues have proposed a direct link between this lack of benefit and the presence of regions of nonfuncti...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/01.AUD.0000058148.27540.D9
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVES:Growing evidence suggests that children who are deaf and use cochlear implants (CIs) can communicate effectively using spoken language. Research has reported that age of implantation and length of experience with the CI play an important role in a predicting a child's linguistic development. In recent years,...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000023
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:This study was designed to evaluate performance stability with test-retest measures of electrical thresholds, electrical maximum acceptable loudness levels, sound-field thresholds, and audition-only speech tests. The hypothesis was that the standard error of measurement differs from one individual to another ...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-199504000-00006
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the additional perceptual benefit provided to children through the use of two cochlear implants in comparison to one after 6 to 13 mo experience with sequential bilateral implants. DESIGN:A second cochlear implant was received by 11 children. The principal selection criteria were being age 4 to 1...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0b013e31806dc194
更新日期:2007-08-01 00:00:00
abstract::In hearing aid research and application it is often necessary to transform the sound pressure level or acoustic gain measured at one physical point (e.g., 2 cc coupler) to an equivalent value at another physical point (e.g., tympanic membrane). Results of currently available studies on various transformations are summ...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/00003446-198902000-00010
更新日期:1989-02-01 00:00:00
abstract::A common element of the psychophysiological research on listening effort is the focus on listening demand as determinant of effort. The article discusses preceding studies and theorizing on effort to show that the link between listening demand and listening effort is moderated by various variables. Moreover, I will pr...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000295
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:Watching a talker's mouth is beneficial for speech reception (SR) in many communication settings, especially in noise and when hearing is impaired. Measures for audiovisual (AV) SR can be valuable in the framework of diagnosing or treating hearing disorders. This study addresses the lack of standardized meth...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000502
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:Channel interaction, the stimulation of overlapping populations of auditory neurons by distinct cochlear implant (CI) channels, likely limits the speech perception performance of CI users. This study examined the role of vocoder-simulated channel interaction in the ability of children with normal hearing (cN...
journal_title:Ear and hearing
pub_type: 杂志文章
doi:10.1097/AUD.0000000000000615
更新日期:2019-03-01 00:00:00