Intravesical epirubicin treatment following TUR in superficial bladder tumours.

Abstract:

OBJECTIVE:To evaluate the effectiveness and tolerability of intravesical epirubicin treatment to prevent recurrence and progression of superficial bladder tumor after TUR. METHODS:44 patients with superficial bladder tumor, 28 primary and 16 recurrent cases were given 50 mg intravesical epirubicin once a week for 8 weeks after TUR. Recurrent cases had not been treated by any intravesical agent before. Follow-up was done by cystoscopy, urine cytology and random biopsies. RESULTS:Local recurrence after treatment was found in 14.28% and 18.75%, and recurrence in another area was found in 21.42% and 31.25% of the primary and recurrent tumor groups respectively. Total recurrence in both groups was 40.91%. No systemic toxicity was observed and local side effects were treated symptomatically. CONCLUSION:Intravesical epirubicin after TUR for superficial bladder tumors especially for the primary ones, is a reliable method that provides effective prophylaxis with tolerable side effects.

journal_name

Arch Esp Urol

authors

Imamoğlu MA,Bakirtaş H,Yiğitbaşi O,Ersoy H,Sertçelik AN

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

1147-53

issue

10

eissn

0004-0614

issn

1576-8260

journal_volume

54

pub_type

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