Two antioxidative lactobacilli strains as promising probiotics.

Abstract:

:Two antioxidative strains tentatively identified as Lactobacillus fermentum, E-3 and E-18, were isolated from intestinal microflora of a healthy child. Survival time of these strains in the presence of reactive oxygen species (ROS), like hydrogen peroxide, superoxide anions and hydroxyl radicals, was significantly increased compared with a non-antioxidative strain, and also was quite similar to a highly ROS resistant strain of Salmonella typhimurium. E-3 and E-8 contain a remarkable level of glutathione, express Mn-SOD, which is important for the prevention of lipid peroxidation, and secrete hydrogen peroxide. Their significant antimicrobial activity combined with antioxidative properties may serve as defensive principles in the intestinal microbial ecosystem and overcome exo- and endogenous oxidative stress.

journal_name

Int J Food Microbiol

authors

Kullisaar T,Zilmer M,Mikelsaar M,Vihalemm T,Annuk H,Kairane C,Kilk A

doi

10.1016/s0168-1605(01)00674-2

subject

Has Abstract

pub_date

2002-02-05 00:00:00

pages

215-24

issue

3

eissn

0168-1605

issn

1879-3460

pii

S0168-1605(01)00674-2

journal_volume

72

pub_type

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