Abstract:
:Two antioxidative strains tentatively identified as Lactobacillus fermentum, E-3 and E-18, were isolated from intestinal microflora of a healthy child. Survival time of these strains in the presence of reactive oxygen species (ROS), like hydrogen peroxide, superoxide anions and hydroxyl radicals, was significantly increased compared with a non-antioxidative strain, and also was quite similar to a highly ROS resistant strain of Salmonella typhimurium. E-3 and E-8 contain a remarkable level of glutathione, express Mn-SOD, which is important for the prevention of lipid peroxidation, and secrete hydrogen peroxide. Their significant antimicrobial activity combined with antioxidative properties may serve as defensive principles in the intestinal microbial ecosystem and overcome exo- and endogenous oxidative stress.
journal_name
Int J Food Microbioljournal_title
International journal of food microbiologyauthors
Kullisaar T,Zilmer M,Mikelsaar M,Vihalemm T,Annuk H,Kairane C,Kilk Adoi
10.1016/s0168-1605(01)00674-2subject
Has Abstractpub_date
2002-02-05 00:00:00pages
215-24issue
3eissn
0168-1605issn
1879-3460pii
S0168-1605(01)00674-2journal_volume
72pub_type
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