Abstract:
:A simple method to synthesize (+/-)-2-O-(4-coumaroyl)-3-(4-hydroxyphenyl)lactic acid (1), a key intermediate in rosmarinic acid biosynthesis in higher plant cells, was established by condensation of protected 4-coumaric acid and (+/-)-3-(4-hydroxyphenyl)lactic acid followed by deprotection. A stable supply of 1 thus attained will lead to biochemical and molecular biological characterization of later steps of rosmarinic acid biosynthesis.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Matsuno M,Nagatsu A,Ogihara Y,Mizukami Hdoi
10.1248/cpb.49.1644subject
Has Abstractpub_date
2001-12-01 00:00:00pages
1644-6issue
12eissn
0009-2363issn
1347-5223journal_volume
49pub_type
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