Abstract:
:A nondestructive, efficient, and rapid method for quantitative analysis of two bioactive components (salidroside and p-tyrosol) in Rhodiola crenulata, a traditional Tibetan medicine, by Fourier transform near-infrared (FT-NIR) spectroscopy was developed. Near-infrared diffuse reflectance spectra in the range of 4000 to 10000 cm(-1) of 50 samples of Rhodiola crenulata with different sources were measured. To get a satisfying result, partial least squares regression (PLSR) was used to establish NIR models for salidroside and p-tyrosol content determination. Different preprocessing methods, including smoothing, taking a second derivative, standard normal variate (SNV) transformation, and multiplicative scatter correction (MSC), were investigated to improve the model accuracy of PLSR. The performance of the two final models (salidroside model and p-tyrosol model) was evaluated by factors such as the values of correlation coefficient (R(2)), root mean square error of prediction (RMSEP), and root mean square error of calibration (RMSEC). The optimal results of the PLSR model of salidroside showed that R(2), RMSEP and RMSEC were 0.99572, 0.0294 and 0.0309, respectively. Meanwhile, in the optimization model of p-tyrosol, the R(2), RMSEP and RMSEC were 0.99714, 0.0154 and 0.0168, respectively. These results demonstrate that FT-NIR spectroscopy not only provides a precise, rapid method for quantitative analysis of major effective constituents in Rhodiola crenulata, but can also be applied to the quality control of Rhodiola crenulata.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Li T,He Xdoi
10.1248/cpb.c15-00558subject
Has Abstractpub_date
2016-01-01 00:00:00pages
289-96issue
4eissn
0009-2363issn
1347-5223journal_volume
64pub_type
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