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Synthesis and structure-activity relationships of oxime neurokinin antagonists: discovery of potent arylamides.

Abstract：

:The structural modification of the benzylic ether region of oxime 1 has resulted in the identification of several novel aryl amides as selective or dual NK(1)/NK(2) antagonists.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Shih NY,Albanese M,Anthes JC,Carruthers NI,Grice CA,Lin L,Mangiaracina P,Reichard GA,Schwerdt J,Seidl V,Wong SC,Piwinski JJ

doi

10.1016/s0960-894x(01)00709-0

subject

Has Abstract

pub_date

2002-01-21 00:00:00

pages

141-5

issue

2

eissn

0960-894X

issn

1464-3405

pii

S0960894X01007090

journal_volume

12

pub_type

杂志文章

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