Epidermal growth factor and TGFalpha promote zebrafish oocyte maturation in vitro: potential role of the ovarian activin regulatory system.

abstract：:Mutations in the GnRH receptor gene (GNRHR) can result in hypogonadotropic hypogonadism in humans. Unlike most mammals, mice lack a second form of GnRH (GnRH2) and a type 2 GnRH receptor. To determine whether the GnRH receptor is critical at all stages of reproduction and whether this receptor has additional physiolog...

journal_title：Endocrinology

authors： Wu S,Wilson MD,Busby ER,Isaac ER,Sherwood NM

更新日期：2010-03-01 00:00:00

abstract：:A series of rat and mouse monoclonal antibodies to the human progesterone receptor (PR) has recently been produced. These antibodies were used for the immunocytochemical identification of PR in several mammalian species including humans. The specificity of the monoclonal antibodies for PR was confirmed by using compet...

journal_title：Endocrinology

authors： Press MF,Greene GL

更新日期：1988-03-01 00:00:00

abstract：:Adrenal cAMP and plasma corticosterone levels were determined in pre-weanling rats subjected to treatment with either ACTH (50 mU/rat) or histamine dihydrochloride (0.2 mg/g body wt). ACTH injection elevated both serum corticosterone and adrenal cAMP levels on all days tested. However, the ACTH-induced elevation of ad...

journal_title：Endocrinology

authors： Cote TE,Yasumura S

更新日期：1975-04-01 00:00:00

abstract：:Pharmacological amounts of 25(s),26-dihydroxyvitamin D3 were administered to normal, vitamin D-replete rats in order to assess its pharmacological activity. Treatment with 25(s),26-dihydroxyvitamin D3 (20 micrograms/day for 1 week) caused a marked and significant fall in the circulating concentration of 1,25-dihydroxy...

journal_title：Endocrinology

authors： Zerwekh JE,Harvey JA,Pak CY

更新日期：1987-11-01 00:00:00

abstract：:Stanniocalcin (STC) is a new mammalian polypeptide hormone and appears to be a regulator of neuronal function. We have already shown that the induction of STC mRNA and protein expression by cAMP is integral to neuroblastoma cell differentiation, particularly neurite outgrowth. In this study, we examined the cAMP pathw...

journal_title：Endocrinology

authors： Yeung HY,Chan DK,Mak NK,Wagner GF,Wong CK

更新日期：2003-10-01 00:00:00

abstract：:In order to study whether changes in adenohypophysial dopamine are only related to PRL release or also to the variation of LH or FSH, dopamine (DA) in the pars distalis was measured during the estrous cycle and after castration of both male and female rats. Catecholamines were assayed using a highly sensitive radioenz...

journal_title：Endocrinology

authors： Chiocchio SR,Chafuen S,Tramezzani JH

更新日期：1980-06-01 00:00:00

abstract：:We have investigated the physiological regulation and functional significance of brain-derived neurotrophic factor (BDNF) in the endocrine melanotrope cells of the pituitary pars intermedia of the amphibian Xenopus laevis, which can adapt its skin color to the light intensity of its environment. In black-adapted anima...

journal_title：Endocrinology

authors： Kramer BM,Cruijsen PM,Ouwens DT,Coolen MW,Martens GJ,Roubos EW,Jenks BG

更新日期：2002-04-01 00:00:00

abstract：:In vertebrates, activation of the GnRH receptor is necessary to initiate the reproductive cascade. However, little is known about the characteristics of GnRH receptors before the vertebrates evolved. Recently genome sequencing was completed for amphioxus, Branchiostoma floridae. To understand the GnRH receptors (GnRHR...

journal_title：Endocrinology

authors： Tello JA,Sherwood NM

更新日期：2009-06-01 00:00:00

abstract：:Cysteamine [2-aminoethanethiol (CySH)] reduces measurable PRL concentrations in vivo and in vitro. Since secretion is also inhibited, CySH may block conversion from a poorly assayable hormone storage form(s) to readily assayable, releasable PRL. This would represent a previously unrecognized mechanism for secretory re...

journal_title：Endocrinology

authors： Lorenson MY,Jacobs LS

更新日期：1984-10-01 00:00:00

abstract：:The ability of ovarian steroids to influence the release of LH was examined after ovariectomy in regularly cycling adult female rats and two types of anovulatory persistent estrous rats: rats treated with 10 mug of testosterone propionate (TP) shortly after birth, and normal rats housed under constant illumination. Tw...

journal_title：Endocrinology

authors： Mennin SP,Gorski RA

更新日期：1975-02-01 00:00:00

abstract：:The effects of lithium on stimulus-induced insulin release and glucose tolerance were examined in intact, unanesthetized, and unrestrained rats with indwelling intravascular catheters. In the first study, a 150-mg iv glucose pulse was administered at 30 min after rapid iv injection of lithium carbonate (1 meq/kg) or v...

journal_title：Endocrinology

authors： Shah JH,Pishdad G

更新日期：1980-11-01 00:00:00

abstract：:The roles of growth hormone and somatomedin in stimulating muscle cell proliferation were investigated in a series of experiments on myoblast growth in culture. At levels 100 times normal circulating concentrations, neither growth hormone nor insulin stimulated growth of rat muscle cells in serum-free medium. In contr...

journal_title：Endocrinology

authors： Florini JR,Nicholson ML,Dulak NC

更新日期：1977-07-01 00:00:00

abstract：:Although polychlorinated biphenyls (PCBs) have been shown to accumulate in the adrenal, little is known about the effects of these endocrine disruptors on adrenal steroidogenesis. Our previous studies showed that high concentrations of PCB126 stimulated CYP11B1 and CYP11B2 mRNA expression and consequently raised corti...

journal_title：Endocrinology

authors： Lin TC,Chien SC,Hsu PC,Li LA

更新日期：2006-03-01 00:00:00

abstract：:Molecular size heterogeneities of PRL and GH in mice of the high mammary tumor C3H/St strain and low mammary tumor C57BL/St strain were compared under different physiological states. At least three size variants, the big (void volume), the intermediate (dimeric), and the little (monomeric) forms, of both hormones were...

journal_title：Endocrinology

authors： Sinha YN

更新日期：1980-12-01 00:00:00

abstract：:Effects of thyroidectomy on Fos-like immunoreactivity (IR) in the rat brain were examined using single and double-label immunocytochemical techniques. In particular, the possibility that Fos might be involved in thyroid hormone regulation of thyrotropin releasing hormone (TRH)-containing neurons located in the parvoce...

journal_title：Endocrinology

authors： Koibuchi N,Gibbs RB,Suzuki M,Pfaff DW

更新日期：1991-12-01 00:00:00

abstract：:Neurosteroids are steroids that are synthesized de novo in the brain and include some classical (adrenal and gonadal steroids) and some unique brain-specific steroids. Neurosteroids are thought to mediate their action through ion gated channel receptors such as gamma-aminobutyric acid(A) and N-methyl-D-aspartate rathe...

journal_title：Endocrinology

authors： Compagnone NA,Bulfone A,Rubenstein JL,Mellon SH

更新日期：1995-11-01 00:00:00

abstract：:Recent evidence suggests that ANF neurons of the hypothalamus are dopamine sensitive, and the catecholamine may exert a direct stimulatory or inhibitory effect on the neurons mediated through D1 or D2 receptors, respectively, in a manner related to the differential dopamine binding sensitivity of the two receptor subt...

journal_title：Endocrinology

authors： Lee D,Huang W,Copolov DL,Lim AT

更新日期：1995-12-01 00:00:00

abstract：:The protein thiol-modifying agent arsenite, a potent activator of stress signaling, was used to examine the involvement of MAPKs in the regulation of cardiac substrate uptake. Arsenite strongly induced p38 MAPK phosphorylation in isolated rat cardiac myocytes but also moderately enhanced phosphorylation of p42/44 ERK ...

journal_title：Endocrinology

authors： Luiken JJ,Momken I,Habets DD,El Hasnaoui M,Coumans WA,Koonen DP,Glatz JF,Bonen A

更新日期：2006-11-01 00:00:00

abstract：:Prolactin has been associated with many effects and has been implicated in the pathogenesis of pregnancy-related hypertensive disorders, although little is known about its vascular effects. The present study was designed to determine the primary effect of prolactin on regional vascular beds and the mechanisms involved...

journal_title：Endocrinology

authors： Molinari C,Grossini E,Mary DA,Uberti F,Ghigo E,Ribichini F,Surico N,Vacca G

更新日期：2007-08-01 00:00:00

abstract：:The ability of different LH-like hormones, such as hCG, PMSG/equine (e) CG, ovine (o) LH, eLH, and rat (r) LH, to bind to and stimulate steroidogenesis in two types of rat gonadal cells was studied under the same experimental conditions. In both Leydig and granulosa cells, the maximal steroidogenic responses elicited ...

journal_title：Endocrinology

authors： Rani CS,Moudgal NR

更新日期：1985-02-01 00:00:00

abstract：:A parotid hormone (PH-A beta) has been isolated and purified from porcine parotid glands. The biological effect of the hormone is the stimulation of a dentinal fluid transport (DFT) in molar teeth of rats. The method for purifying the PH-A beta includes: extraction at pH 7 and 5, ultrafiltration through Amicon membran...

journal_title：Endocrinology

authors： Tieche JM,Leonora J,Steinman RR

更新日期：1980-06-01 00:00:00

abstract：:In Teleost fish, development, growth, and reproduction are influenced by the daily and seasonal variations of photoperiod and temperature. Early in vivo studies indicated the pineal gland mediates the effects of these external factors, most probably through the rhythmic production of melatonin. The present investigati...

journal_title：Endocrinology

authors： Falcón J,Besseau L,Fazzari D,Attia J,Gaildrat P,Beauchaud M,Boeuf G

更新日期：2003-10-01 00:00:00

abstract：:The GnRH neurosecretory system undergoes marked structural and functional changes throughout life. The initial goal of this study was to examine the neuroanatomical relationship between GnRH neurons and a glycoprotein implicated in neuroplasticity, the polysialylated form of neural cell adhesion molecule (PSA-NCAM). U...

journal_title：Endocrinology

authors： Viguié C,Jansen HT,Glass JD,Watanabe M,Billings HJ,Coolen L,Lehman MN,Karsch FJ

更新日期：2001-03-01 00:00:00

abstract：:Although the neurohypophyseal hormone oxytocin (OT) is best know for its role in reproduction, OT also stimulates natriuresis at physiological plasma levels. This effect is mediated via specific renal OT receptors (OTRs). In the present study, we have characterized rat renal OTR gene transcripts and assessed their reg...

journal_title：Endocrinology

authors： Breton C,Neculcea J,Zingg HH

更新日期：1996-07-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1), in the form of either GLP-1-(7-36)amide or GLP-1-(7-37), has been shown to potently stimulate insulin release in a glucose-dependent manner and is suggested to be a physiological incretin. To explore the mechanisms by which GLP-1-(7-36)amide stimulates insulin release, we investigated ...

journal_title：Endocrinology

authors： Yada T,Itoh K,Nakata M

更新日期：1993-10-01 00:00:00

abstract：:We have previously shown that in reaggregate cell cultures of 14-day-old female rat pituitary, LHRH is capable of stimulating lactotrophs to enter the S-phase of the cell cycle, and that this effect is mediated by paracrine growth factors secreted from gonadotrophs. In the present report we describe the isolation, pur...

journal_title：Endocrinology

authors： Tilemans D,Andries M,Proost P,Devreese B,Van Beeumen J,Denef C

更新日期：1994-07-01 00:00:00

abstract：:In previous studies we found that plasma angiotensinogen levels were reduced by lesions of the hypothalamic paraventricular nuclei. To determine if the decrease was caused by decreased secretion of hormones that normally stimulate angiotensinogen secretion by the liver, we correlated the changes in plasma angiotensino...

journal_title：Endocrinology

authors： Kjos T,Gotoh E,Tkacs N,Shackelford R,Ganong WF

更新日期：1991-08-01 00:00:00

abstract：:Rabbit hearts perfused by the Langendorff technique were studied. The addition of ovine prolactin (NIH-P-S-10) to the perfusate in a concentration of 50 ng/ml produced rapid increases in both the amplitude and rate of contraction in 33 adult male hearts studied in winter. Prepubertal male animals showed no response, a...

journal_title：Endocrinology

authors： Nassar BA,Horrobin DF,Tynan M,Manku MS,Davies PA

更新日期：1975-10-01 00:00:00

abstract：:We have investigated the effect of GH on microtubular physiology in Chinese hamster ovary (CHO) cells stably transfected with the complementary DNA for the rat GH receptor (CHO-GHR(1-638)). We show here that after 30 min of human GH (hGH) treatment of CHO-GHR(1-638) cells, there was a significant increase in the level...

journal_title：Endocrinology

authors： Goh EL,Pircher TJ,Lobie PE

更新日期：1998-10-01 00:00:00

abstract：:Androgens and estrogens play major roles in cell differentiation, cell growth, and peptide secretion in steroid target tissues. In addition to the binding of these hormones to their receptors, formation and metabolism are important in the action of steroids. Metabolism of the potent steroid hormones includes glucuroni...

journal_title：Endocrinology

authors： Turgeon D,Carrier JS,Lévesque E,Hum DW,Bélanger A

更新日期：2001-02-01 00:00:00