当前位置： SCI文献检索 > ACTA ODONTOLOGICA SCANDINAVICA期刊下所有文献 > A revisit of mucosal IgA immunity and oral tolerance.

A revisit of mucosal IgA immunity and oral tolerance.

Abstract：

:Induction of mucosal immunity by oral immunization with protein antigen alone is difficult: potent mucosal adjuvants, vectors, or other special delivery systems are required. Cholera toxin (CT) has been shown to be an effective adjuvant for the development of mucosal vaccines and, when given with vaccine, induces both mucosal and systemic immune responses via a Th2 cell-dependent pathway. However, and in addition to potential type-I hypersensitivity, a major concern for use of mucosal adjuvants such as CT is that this molecule is not suitable for use in humans because of its inherent toxicity. When we examined the potential toxicity of CT for the central nervous system, both CT and CT-B accumulated in the olfactory nerves/epithelium and olfactory bulbs of mice when given by the nasal route. The development of effective mucosal vaccines for the elderly is also an important issue; however, only limited information is available. When mucosal adjuvanticity of CT was evaluated in aged mice, an early immune dysregulation was evident in the mucosal immune system. The present review discusses these potential problems for effective mucosal vaccine development. Tolerance represents the most common and important response of the host to environmental antigens, including food and commensal bacterial components, for the maintenance of an appropriate immunological homeostasis. We have examined whether Peyer patches could play a more important role for the maintenance of oral tolerance. Using Peyer patch-null mice, we found that mice lacking this gut-associated lymphoid tissue retained their capability to produce secretory IgA antibodies but did not develop normal oral tolerance to protein antigens.

journal_name

Acta Odontol Scand

journal_title

Acta odontologica Scandinavica

authors

Fujihashi K,Kato H,van Ginkel FW,Koga T,Boyaka PN,Jackson RJ,Kato R,Hagiwara Y,Etani Y,Goma I,Fujihashi K,Kiyono H,McGhee JR

doi

10.1080/000163501750541174

subject

Has Abstract

pub_date

2001-10-01 00:00:00

pages

301-8

issue

5

eissn

0001-6357

issn

1502-3850

journal_volume

59

pub_type

杂志文章,评审

相关文献

ACTA ODONTOLOGICA SCANDINAVICA文献大全
  • The depth of the lingual fossa in permanent maxillary incisors of East Greenland Eskimos. II. Side asymmetry, sex differences, comparison of centrals and laterals and anthropologic aspects.

    abstract：:Maxillary incisor lingual fossa depth was measured on casts of East Greenland Eskimo dentitions. No directional side asymmetry was found. The present study is the only which shows mean lingual fossa depth to be significantly deeper in the female than in the male. Larger incisor strength in the females is functional as...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358209019818

    authors： Aas IH

    更新日期：1982-01-01 00:00:00

  • Associations of alveolar bone loss and interleukin-1β levels in one- and two-stage surgical procedures: a randomized prospective trial.

    abstract：OBJECTIVE:Dental implants have been widely and successfully used in recent years as an alternative treatment for removable and fixed dental prostheses. The aim of this randomized prospective study was to determine the alveolar bone loss rate (ABLR) and IL-1β levels in one- and two-stage surgical procedures. MATERIALS ...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章,随机对照试验

    doi：10.1080/00016357.2017.1367959

    authors： Talo Yildirim T,Acun Kaya F,Yokus B,Colak M,Ozdemir Kaya E,Tekin G,Saribas E,Uysal E,Guncu GN

    更新日期：2017-11-01 00:00:00

  • Early developmental traits in class II malocclusion.

    abstract：:The occlusal traits of Class II occlusion in the deciduous dentition include distal terminal plane of the second deciduous molars, distal canine relation, large overjet, and large overbite. Other findings are narrow upper dental arch and maxillary base and poor anterior spacing. Skeletally, Class II children differ le...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章,评审

    doi：10.1080/000163598428356

    authors： Varrela J

    更新日期：1998-12-01 00:00:00

  • Effects of different irrigating solutions and disinfection methods on push-out bond strengths of fiber posts.

    abstract：OBJECTIVE:The aim of this study was to evaluate the effects of various irrigating solutions and photoactivated disinfection (PAD) on the push-out bond strengths of fiber posts to root dentin. MATERIALS AND METHODS:Thirty-two human teeth were divided into eight groups, as follows: (1) irrigation with physiologic saline...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016357.2014.906651

    authors： Ertas H,Ok E,Uysal B,Arslan H

    更新日期：2014-11-01 00:00:00

  • Fluoride uptake in enamel and dentin surfaces exposed to a fluoride-containing amalgam in vitro. a proton microprobe analysis.

    abstract：:Proton microprobe analysis was used to determine the fluoride concentrations in enamel and dentin surfaces exposed to a fluoride-containing and a conventional amalgam in vitro. After seven weeks of exposure, a considerable fluoride uptake was demonstrated from the fluoride-containing amalgam. The fluoride deposition w...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358009033594

    authors： Tveit AB,Lindh U

    更新日期：1980-01-01 00:00:00

  • Cracks in gold crowns cemented on amalgam restorations.

    abstract：:Twenty-seven gold crowns, removed from patients with problems such as diffuse pain and metallic taste, have been examined. The gold crowns were made of an ordinary casting gold alloy, type III. The crowns were built on amalgam cores or big amalgam fillings. Eight of these crowns had cracks beginning at the cervical ma...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358509064134

    authors： Odén A,Tullberg M

    更新日期：1985-03-01 00:00:00

  • Prenatal traces of aberrant neurofacial growth.

    abstract：:The interrelation between the development of the brain/peripheral nerves and that of the surrounding bone tissue is termed neuro-osteology. In orthodontic and pediatric practice the development of the hard tissues is evaluated radiographically, but the development of the neural tissue within the bone tissue is not eva...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章,评审

    doi：10.1080/000163598428257

    authors： Kjaer I

    更新日期：1998-12-01 00:00:00

  • Defensive characteristics in individuals with amalgam illness as measured by the percept-genetic method Defense Mechanism Test.

    abstract：:Twenty patients complaining of symptoms deriving from their amalgam fillings and a non-patient group were assessed by means of the perceptual projective Defense Mechanism Test (DMT). The test protocols were scored for 130 DMT variables and analyzed by means of the multivariate statistical method Partial Least Squares ...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016359609003520

    authors： Henningsson M,Sundbom E

    更新日期：1996-06-01 00:00:00

  • Effect of fluoride-containing alginates and gels on the acid resistance of demineralized human enamel.

    abstract：:A series of in vitro studies were carried out to determine the effect of commerically available alginate impression materials and gels on enamel solubility. This was performed by 4-min topical application of the tested products on partially demineralized enamel surfaces. The difference in the amounts of calcium and ph...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358408993869

    authors： Hattab F

    更新日期：1984-06-01 00:00:00

  • Clinical characterization of women with burning mouth syndrome in a case-control study.

    abstract：OBJECTIVE:Burning mouth syndrome (BMS) is a chronic orofacial pain disorder that is defined by a burning sensation in the oral mucosa. The aim of this study was to investigate the underlying factors, clinical characteristics and self-reported oral and general health factors associated with BMS. MATERIAL AND METHODS:Fi...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016357.2017.1420226

    authors： Acharya S,Carlén A,Wenneberg B,Jontell M,Hägglin C

    更新日期：2018-05-01 00:00:00

  • Genetics of inflammatory bowel disease: from bench to bedside?

    abstract：:Epidemiological data, particularly concordance rates in twin pairs and in multiply affected families, provide strong evidence that both genetic and environmental influences are important in the development of the chronic intestinal inflammation characteristic of Crohn disease and ulcerative colitis. Furthermore, suppl...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章,评审

    doi：10.1080/000163501750266800

    authors： Satsangi J

    更新日期：2001-06-01 00:00:00

  • Enamel remineralization effect of a dentifrice containing calcium sodium phosphosilicate: an optical coherence tomography observation.

    abstract：OBJECTIVE:The purpose of this study was to examine the effects of a dentifrice containing 5% calcium sodium phosphosilicate (CSP) on the remineralization of the enamel using optical coherence tomography (OCT). MATERIALS AND METHODS:Bovine incisors were sliced and shaped in a rectangular form. One group of five specime...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016357.2016.1277588

    authors： Matsuyoshi S,Murayama R,Akiba S,Yabuki C,Takamizawa T,Kurokawa H,Miyazaki M

    更新日期：2017-04-01 00:00:00

  • Effect of temporary cements on the microtensile bond strength of self-etching and self-adhesive resin cement.

    abstract：OBJECTIVE:The aim of this study was to evaluate the microtensile bond strength (µTBS) of self-etching and self-adhesive resin cement systems to dentin affected by the presence of remnants of either eugenol-containing or eugenol-free temporary cements. MATERIALS AND METHODS:Thirty extracted teeth were obtained and a fl...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016357.2014.903518

    authors： Carvalho EM,Carvalho CN,Loguercio AD,Lima DM,Bauer J

    更新日期：2014-11-01 00:00:00

  • Avoidance of dental visits: the predictive validity of three dental anxiety scales.

    abstract：:The purpose of this study was to determine the sensitivity, specificity, positive and negative predictive values for Corah's Dental Anxiety Scale (DAS) and two modified versions of it (MDAS; MDAS/4). A questionnaire was mailed to a simple random sample of 1,190 25-year-old residents in the west of Norway in 1997. Half...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016350050217091

    authors： Haugejorden O,Klock KS

    更新日期：2000-12-01 00:00:00

  • Caries-preventive effect of an oral health program for preschool children in a low socio-economic, multicultural area in Sweden: results after one year.

    abstract：:The aim of this study was to evaluate the caries-preventive effect of an oral health program for preschool children living in a multicultural, low socio-economic area. In total, 804 2-year-old children were invited and recalled every 3rd month to an outreach facility for parent education and toothbrushing instruction....

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016350510019900

    authors： Wennhall I,Mårtensson EM,Sjunnesson I,Matsson L,Schröder U,Twetman S

    更新日期：2005-06-01 00:00:00

  • On the causes of traumatic dental injuries with special reference to sports accidents in a sample of Finnish children. A study of a clinical patient material.

    abstract：:Causes of traumatic dental injuries were studied in a sample of 321 Finnish children with injured permanent incisors. In girls the most common cause was falls (36.7%), and with boys sports (33.6%). Among the sports accidents, gymnastics dominated for girls and ice hockey for boys. Bicycling was also a markedly frequen...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358009004714

    authors： Järvinen S

    更新日期：1980-01-01 00:00:00

  • Root length, crown height, and root morphology in Turner syndrome.

    abstract：:Root length, crown height, and root morphology were studied on intraoral and panoramic radiographs in 33 Turner syndrome patients aged 7.0-16.7 years, subdivided on the basis of karyotype. Thirty-three normal girls aged 10.2-16.4 years served as controls. In the 45X patients and, with the exception of a few teeth, als...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016359409029043

    authors： Midtbø M,Halse A

    更新日期：1994-10-01 00:00:00

  • Do self-assessed oral health and treatment need associate with clinical findings? Results from the Finnish Nationwide Health 2000 Survey.

    abstract：OBJECTIVE:To associate self-assessed oral health and treatment need with clinically determined findings. MATERIALS AND METHODS:As part of the Finnish nationwide comprehensive Health 2000 Survey, the present cross-sectional study included dentate participants aged 30-64 years who self-assessed their oral health and tre...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016357.2014.923110

    authors： Tseveenjav B,Suominen AL,Varsio S,Knuuttila M,Vehkalahti MM

    更新日期：2014-11-01 00:00:00

  • The importance of measuring toothpaste abrasivity in both a quantitative and qualitative way.

    abstract：OBJECTIVE:To evaluate the relative abrasivity of different toothpastes and polishing pastes both qualitatively and quantitatively. MATERIALS AND METHODS:Acrylic plates were exposed to brushing in a brushing machine with a toothpaste/water slurry for 1 and 6 h. Twelve different toothpastes were used and also four diffe...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016357.2012.696693

    authors： Johannsen G,Tellefsen G,Johannsen A,Liljeborg A

    更新日期：2013-05-01 00:00:00

  • Effects of dental attendance frequency in heavy and low private care-using young adults.

    abstract：:In Finland, adults born in 1961 or later were progressively entitled to subsidies for dental care from private practitioners during 1986-90, while at the same time having access to care in the Public Dental Service. The aim of this study was to compare the effects of attendance frequency of private dental care on trea...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/000163502753509473

    authors： Suominen-Taipale AL,Widström E

    更新日期：2002-03-01 00:00:00

  • Methods for evaluation of working and setting times of periodontal dressings.

    abstract：:Three different methods were used to determine working and setting times of periodontal dressings. The Gillmore needle and the rheometer employed were not suitable for recording setting reactions. A penetration test was found applicable for determination of working and setting times for all three dressings although th...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016357909004701

    authors： Haugen E,Espevik S,Mjör IA

    更新日期：1979-01-01 00:00:00

  • Oral candidosis--frequency, treatment and relapse tendency in a group of psychiatric inpatients.

    abstract：:Candida fungi are frequent in the oral cavity, especially in denture wearers. The infection can cause serious complications in elderly or debilitated subject. The present experimental group consisted of 81 female psychiatric patients (35--91 years of age). In addition to a clinical examination, smears from the palate,...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016357909004708

    authors： Jacobsen S,Bryhni IL,Gjermo P

    更新日期：1979-01-01 00:00:00

  • On the presence and localization of epidermal and nerve growth factors in human whole saliva.

    abstract：:Using antibodies to mouse submandibular epidermal growth factor (EFG) and nerve growth factor (NGF), immunohistochemical studies were performed on sections of flash-frozen human whole saliva in both light and transmission electron microscopy. Light microscopy showed the presence of overall network-like immunoreactions...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358909007714

    authors： Glantz PO,Meenaghan MA,Hyun KH,Wirth SM

    更新日期：1989-10-01 00:00:00

  • The effect of commercial conjugated linoleic acid products on experimental periodontitis and diabetes mellitus in Wistar rats.

    abstract：OBJECTIVE:The aim of present study was to determine the effects of conjugated linoleic acid enriched milk on alveolar bone loss, hyperglycaemia, oxidative stress and apoptosis in ligature-induced periodontal disease in diabetic rat model. METHODS:Wistar rats were divided into six experimental groups: 1; non-ligated (N...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016357.2016.1244355

    authors： Balci Yuce H,Akbulut N,Ocakli S,Kayir O,Elmastas M

    更新日期：2017-01-01 00:00:00

  • Strategic implementation of dental infection control in resource-poor jurisdictions during COVID-19 pandemic: a perspective from South Africa.

    abstract：BACKGROUND:The coronavirus disease-19 (COVID-19) pandemic caused by the severe acute respiratory syndrome Coronavirus -2 is unceasing, and the consensus is that the dental profession has to co-exist with this vicious foe for the foreseeable future. Dental professionals in resource poor countries, as opposed to those in...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016357.2020.1804073

    authors： Blignaut E,Nemutandani S,Samaranayake L

    更新日期：2020-11-01 00:00:00

  • Abrasion of acrylic veneers by simulated toothbrushing.

    abstract：:The abrasion responses were tested on four acrylic veneer materials, K + B Plus, K + B 75, Isosit, and Ivocron. The studies were performed in two independent research laboratories. Two different brushing machines were used with an abrasive slurry. The results were used for comparing the degree of abrasion for the resi...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358409033617

    authors： Xu HC,Söremark R,Wiktorsson G,Wang T,Liu WY

    更新日期：1984-12-01 00:00:00

  • Effect of storage duration on tensile bond strength of acrylic or silicone-based soft denture liners to a processed denture base polymer.

    abstract：OBJECTIVE:To investigate the effect of storage duration on the tensile bond strength of acrylic and silicone-based denture base materials with liners either heat-cured or auto-cured. MATERIAL AND METHODS:The denture liners investigated were Vertex soft (acrylic-based, heat-cured), Coe soft (acrylic-based, auto-cured),...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.1080/00016350510019667

    authors： Meşe A,Güzel KG,Uysal E

    更新日期：2005-02-01 00:00:00

  • Tubular occlusion of simulated hypersensitive dentin by the combined use of ozone and desensitizing agents.

    abstract：OBJECTIVE:Ozone was suggested for treatment of hypersensitive dentin. The purpose of this study was to investigate the effect of ozone, with or without the use of desensitizing agents, on patency and occlusion of simulated hypersensitive dentin. MATERIALS AND METHODS:Sixty standardized dentin slabs were randomly divid...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章,随机对照试验

    doi：10.3109/00016357.2011.572290

    authors： Raafat Abdelaziz R,Mosallam RS,Yousry MM

    更新日期：2011-11-01 00:00:00

  • The role of sutures in normal and abnormal craniofacial growth.

    abstract：:The paper is a shortened version of a paper read at the symposium on craniofacial growth, in which the literature on various aspects of sutures was reviewed. Suture development, structure, growth, and closure are covered, and the response of sutures to orthopedic forces and their role in craniosynostosis exemplified. ...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章,评审

    doi：10.3109/00016359509005965

    authors： Persson M

    更新日期：1995-06-01 00:00:00

  • Bacteriological studies on endodontic paper points.

    abstract：:Four brands of endodontic paper points were subjected to tests for sterility, antibacterial activity, and suitability as vehicles for bacteriological sampling procedures. No brand showed growth in the sterility assay. One brand showed weak but reproducible antibacterial activity. Recovery of viable bacteria after abso...

    journal_title：Acta odontologica Scandinavica

    pub_type： 杂志文章

    doi：10.3109/00016358509046492

    authors： Orstavik D,Möller B

    更新日期：1985-05-01 00:00:00