Hypomagnesemic hypocalcemia secondary to renal magnesium wasting.

Abstract:

:Two patients developed severe hypomagnesemia, hypocalcemia, and hypokalemia as a result of renal wasting of magnesium and potassium shortly after being treated with large doses of gentamicin. When therapy with gentamicin was discontinued renal loss of magnesium and potassium ceased, and serum calcium, magnesium, and potassium returned toward normal. Serum immunoreactive parathyroid hormone levels were inappropriately low during the episodes of hypocalcemia. Both patients represent examples of hypomagnesemic hypocalcemia induced by inappropriate magnesuria, possibly caused by gentamicin. These observations suggest that serum calcium, magnesium, and potassium should be monitored during gentamicin therapy.

journal_name

Ann Intern Med

authors

Bar RS,Wilson HE,Mazzaferri EL

doi

10.7326/0003-4819-82-5-646

subject

Has Abstract

pub_date

1975-05-01 00:00:00

pages

646-9

issue

5

eissn

0003-4819

issn

1539-3704

journal_volume

82

pub_type

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