当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > The pharmacokinetics and efficacy of different estrogens are not equivalent.

The pharmacokinetics and efficacy of different estrogens are not equivalent.

Abstract：

:In the next decade many women will turn to the medical community for advice on maintaining or improving health after menopause. Estrogen replacement therapy, with or without progestins, alleviates menopausal symptoms, prevents or manages osteoporosis, and reduces the increased cardiovascular disease risk that results from estrogen deficiency caused by ovarian decline. Although several estrogen replacement products are available, the pharmacokinetics and efficacy of these products may vary depending on either the estrogen formulation or the route of administration, or both. For example, oral estrogens, which elicit a marked hepatic response, induce greater beneficial effects on serum lipoproteins than transdermal estrogens, which circumvent first-pass liver metabolism. Oral conjugated estrogens and transdermal estradiol increase bone density and prevent bone loss. This article summarizes the studies comparing estrogen formulations and discusses the differential effects of various estrogen products that promote postmenopausal health.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Ansbacher R

doi

10.1067/mob.2001.109656

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

255-63

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(01)53165-8

journal_volume

184

pub_type

杂志文章,评审

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • A simple estimated fetal weight equation based on real-time ultrasound measurements of fetuses less than thirty-four weeks' gestation.

    abstract：:Based on ultrasonographic mensuration, a number of equations have previously been devised for the purpose of estimating fetal weights. The objective of this study was to develop a mathematical equation that is simple, accurate, and easy to use when applied to preterm or low-birth weight fetuses (less than 2,500 gm). R...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(83)91195-x

    authors： Thurnau GR,Tamura RK,Sabbagha R,Depp OR 3rd,Dyer A,Larkin R,Lee T,Laughlin C

    更新日期：1983-03-01 00:00:00

  • Amniotic fluid tests for fetal maturity in normal and abnormal pregnancies.

    abstract：:Amniotic fluid creatinine, percentage of lipid-positive cells, and L/S ratio were determined on 285 samples from normal pregnancies and 222 samples from abnormal pregnancy states (Rh isoimmunization, diabetes, hypertensive disorders, intrauterine growth retardation, and hydramnios). In normal pregnancy the coefficient...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(76)90777-8

    authors： Doran TA,Malone RM,Benzie RJ,Owen VJ,Thompson DW,New ML

    更新日期：1976-07-01 00:00:00

  • Maternal obesity and risk of stillbirth: a metaanalysis.

    abstract：:We conducted this metaanalysis to summarize the available epidemiologic evidence on the relationship between maternal overweight and obesity and the risk of stillbirth. We identified studies from 3 sources: (1) a PubMed search of relevant articles that were published between January 1980 and September 2005, (2) refere...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.ajog.2007.03.027

    authors： Chu SY,Kim SY,Lau J,Schmid CH,Dietz PM,Callaghan WM,Curtis KM

    更新日期：2007-09-01 00:00:00

  • Carboplatin and paclitaxel for the treatment of advanced or recurrent endometrial cancer.

    abstract：OBJECTIVE:The purpose of this study was to determine the activity and toxicity of carboplatin and paclitaxel (taxol) in the treatment of advanced or recurrent endometrial cancer. STUDY DESIGN:This was a retrospective review of 18 consecutive patients with advanced (stage 4) or recurrent endometrial adenocarcinoma that...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.12.032

    authors： Akram T,Maseelall P,Fanning J

    更新日期：2005-05-01 00:00:00

  • Elevated serum ferritin in the altered ferrokinetics of toxemia of pregnancy.

    abstract：:The serum concentration of ferritin in 11 patients with toxemia of pregnancy was compared to that of normal women in the early third trimester of pregnancy and in labor at term. The mean concentration of ferritin for toxemic patients was 91.8 ng/ml compared to 18.4 ng/ml and 19.4 ng/ml for the two control groups, resp...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90247-2

    authors： Entman SS,Richardson LD,Killam AP

    更新日期：1982-10-15 00:00:00

  • The epidemiology of threatened preterm labor: a prospective cohort study.

    abstract：OBJECTIVE:The purpose of this study was to describe the occurrence, timing, and outcomes of hospital-based diagnoses of preterm labor. STUDY DESIGN:Administrative records identified hospital admissions for preterm labor among 2534 women in an ongoing cohort study. Factors that were considered risks for prematurity wer...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.12.055

    authors： McPheeters ML,Miller WC,Hartmann KE,Savitz DA,Kaufman JS,Garrett JM,Thorp JM

    更新日期：2005-04-01 00:00:00

  • Postpartum intrauterine device insertion and postpartum tubal sterilization in the United States.

    abstract：OBJECTIVE:The purpose of this study was to estimate US rates of postpartum intrauterine device (IUD) insertion and postpartum tubal sterilization. STUDY DESIGN:Data from the 2001-2008 Nationwide Inpatient Sample were used to identify delivery hospitalizations with IUD insertion or tubal sterilization procedure codes. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2011.08.004

    authors： Whiteman MK,Cox S,Tepper NK,Curtis KM,Jamieson DJ,Penman-Aguilar A,Marchbanks PA

    更新日期：2012-02-01 00:00:00

  • Prolactin levels in nursing mothers.

    abstract：:Plasma prolactin (hPRL) concentration was measured in four nursing mothers during 24 hour periods. Blood was collected via indwelling catheters and sleep and nursing periods were recorded. Elevated hRPL levels and amenorrhea were seen for as long as 13 months post partum in mothers whose infants nursed frequently. One...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(78)90594-x

    authors： Bunner DL,VAnderlaan EF,VAnderlaan WP

    更新日期：1978-06-01 00:00:00

  • Prognostic factors and complication rates for cervical cerclage: a review of 482 cases.

    abstract：:Charts from 482 singleton pregnancies undergoing cerclage placement in patients over a 6-year period were reviewed. Cervical dilatation at time of surgery, number of previous spontaneous losses, and gestational age at placement were key determinants of outcome. The most frequent complication, premature rupture of the ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(91)90283-w

    authors： Treadwell MC,Bronsteen RA,Bottoms SF

    更新日期：1991-09-01 00:00:00

  • Defining the role of fluorescence in situ hybridization on uncultured amniocytes for prenatal diagnosis of aneuploidies.

    abstract：OBJECTIVE:This study examines the role of fluorescence in situ hybridization on uncultured amniocytes for prenatal diagnosis in a population at high risk for aneuploidies. STUDY DESIGN:All patients undergoing amniocentesis for fetal structural abnormality on ultrasonographic examination (performed from 13 to 39 weeks)...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(97)70600-8

    authors： D'Alton ME,Malone FD,Chelmow D,Ward BE,Bianchi DW

    更新日期：1997-04-01 00:00:00

  • Effect of maternal docosahexaenoic acid supplementation on postpartum depression and information processing.

    abstract：OBJECTIVE:The purpose of this study was to determine the effect of docosahexaenoic acid supplementation on plasma phospholipid docosahexaenoic acid content and indices of depression and information processing for women who breast-feed. STUDY DESIGN:Mothers who planned to breast-feed their infants were assigned randoml...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mob.2003.275

    authors： Llorente AM,Jensen CL,Voigt RG,Fraley JK,Berretta MC,Heird WC

    更新日期：2003-05-01 00:00:00

  • Childhood lead poisoning prevention through prenatal housing inspection and remediation in St. Louis, MO.

    abstract：OBJECTIVE:We assessed the screening and remediation of home lead hazards prenatally in a high-risk population, hypothesizing that average blood-lead level and the number of poisonings would drop by 25%. STUDY DESIGN:One hundred fifty-two women underwent prenatal home inspections by certified lead inspectors. The hazar...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2012.01.001

    authors： Berg DR,Eckstein ET,Steiner MS,Gavard JA,Gross GA

    更新日期：2012-03-01 00:00:00

  • Validation of algorithm to identify American Indian/Alaska Native pregnant women at risk from pandemic H1N1 influenza.

    abstract：:Pregnant women and American Indian and Alaska Native people are at elevated risk of severe disease and mortality from 2009 pandemic influenza A/H1N1. We validated an electronic health record-based algorithm used by Indian Health Service to identify pregnant women in near real-time surveillance of pandemic influenza A/...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2011.03.004

    authors： Penman-Aguilar A,Tucker MJ,Groom AV,Reilley BA,Klepacki S,Cullen T,Gebremariam C,Redd JT

    更新日期：2011-06-01 00:00:00

  • Atrial natriuretic factor: the effects of pregnancy and a high-salt diet on atrial levels.

    abstract：:The chronic and relatively acute changes in blood volume that occur during pregnancy and post partum may be associated with alterations in the content of atrial natriuretic factor in the atria. We measured the concentration of atrial natriuretic factor in the right and left atria of virgin, pregnant, and postpartum Sp...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(89)90937-x

    authors： Castro LC,Arora CP,Davis JL,Hobel CJ,Parvez H

    更新日期：1989-12-01 00:00:00

  • Maternal and fetal immune responses to human trophoblast antigens.

    abstract：:Maternal and fetal cord leukocytes were tested in cytotoxicity assays against cultured autochthonous trophoblast cells. Significant lysis occurred with both categories of leukocyte, but the degree of cytotoxicity was less with fetal cells. These results suggest reduced fetal immunocompetence, the presence of fetal sup...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(80)90251-3

    authors： Taylor PV

    更新日期：1980-10-01 00:00:00

  • Use of DNA hybridization to detect vaginal pathogens associated with bacterial vaginosis among asymptomatic pregnant women.

    abstract：OBJECTIVE:The purpose of this study was to determine whether microbial DNA hybridization is a useful method to study bacterial vaginosis in asymptomatic pregnant women. STUDY DESIGN:Vaginal specimens were collected at <26 weeks' gestation from 230 women, and analyzed for bacterial vaginosis by both Gram stain using Nu...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2005.01.068

    authors： Boggess KA,Trevett TN,Madianos PN,Rabe L,Hillier SL,Beck J,Offenbacher S

    更新日期：2005-09-01 00:00:00

  • Postmolar surveillance at a trophoblastic disease center that serves indigent women.

    abstract：OBJECTIVE:The purpose of this study was to determine compliance with postmolar pregnancy surveillance in our indigent population. STUDY DESIGN:Data for all women who were diagnosed with molar pregnancy from January 1996 through December 2000 were entered prospectively into a database. After remission, postmolar pregna...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2003.297

    authors： Allen JE,King MR,Farrar DF,Miller DS,Schorge JO

    更新日期：2003-05-01 00:00:00

  • The variability of viability: the effect of physicians' perceptions of viability on the survival of very low--birth weight infants.

    abstract：:Physicians who deliver babies in Alabama were surveyed to determine their level of knowledge about the survival of low--birth weight/early gestational age infants. These estimates of neonatal survival were compared to the actual neonatal survival rates at local hospitals and at the regional perinatal centers in Alabam...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90114-4

    authors： Goldenberg RL,Nelson KG,Dyer RL,Wayne J

    更新日期：1982-07-15 00:00:00

  • Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint.

    abstract：OBJECTIVE:The purpose of this study was to test whether a quantitative high-throughput molecular screen can be used to probe human endometrium and initiate the development of molecular diagnostic tools with potential for identification of therapeutic targets in women with menstrual complaints. STUDY DESIGN:Endometrium...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.05.002

    authors： Critchley HO,Robertson KA,Forster T,Henderson TA,Williams AR,Ghazal P

    更新日期：2006-08-01 00:00:00

  • Maternal oxygen transport variables during the third trimester of normal pregnancy.

    abstract：OBJECTIVE:The aim of this study was to measure and calculate oxygen transport variables in uncomplicated term pregnancies. STUDY DESIGN:Ten normotensive primiparous women between 36 and 38 weeks' gestation underwent pulmonary and radial arterial catheterization as part of a larger study. Seven women had studies repeat...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70223-1

    authors： Hankins GD,Clark SL,Uckan E,Van Hook JW

    更新日期：1999-02-01 00:00:00

  • Blunt vs. sharp uterine expansion at lower segment cesarean section delivery: a systematic review with metaanalysis.

    abstract：OBJECTIVE:Blunt vs sharp expansion of the uterine incision at cesarean delivery has been investigated as a technique primarily to reduce intraoperative blood loss. The objective of this systematic review was to compare the effects of either intervention on maternal outcomes. STUDY DESIGN:A systematic review with metaa...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.ajog.2012.10.886

    authors： Xu LL,Chau AM,Zuschmann A

    更新日期：2013-01-01 00:00:00

  • The effect of live and web-based education on the accuracy of blood-loss estimation in simulated obstetric scenarios.

    abstract：OBJECTIVE:Visual estimation of blood loss has been shown to be inaccurate. The objective of this study was to evaluate the impact of a didactic training program on the accuracy of the estimation of blood loss and to compare the effectiveness of training provided by a web-based vs live session. STUDY DESIGN:Multidiscip...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2009.10.881

    authors： Toledo P,McCarthy RJ,Burke CA,Goetz K,Wong CA,Grobman WA

    更新日期：2010-04-01 00:00:00

  • Fetal plasma interferon gamma concentration in normal pregnancy.

    abstract：OBJECTIVE:Our purpose was to investigate changes with gestation in fetal plasma interferon gamma concentration. STUDY DESIGN:A cross-sectional study at the Harris Birthright Research Centre for Fetal Medicine, London, was performed. Enzyme-linked immunoassay was used to measure plasma concentration in 54 fetal blood s...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)90774-1

    authors： Abbas A,Thilaganathan B,Buggins AG,Layton DM,Nicolaides KH

    更新日期：1993-05-01 00:00:00

  • A perspective on progestogens in oral contraceptives.

    abstract：:Steroid contraception was developed in the late 1950s and introduced into use in the early 1960s. It soon became apparent that estroprogestational agents had adverse systemic effects, mainly on the cardiovascular and blood coagulation system. During the 1970s, new contraceptive agents were developed that contained 3...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(16)32475-9

    authors： Spellacy WN

    更新日期：1982-03-15 00:00:00

  • Cryosurgery for the treatment of cervical intraepithelial neoplasia.

    abstract：:Cryosurgery was used to treat 208 patients with cervical intraepithelial neoplasia. These patients were referred to our Colposcopy Clinic for investigation of an abnormal Papanicolaou smear. Prior to treatment a colposcopically directed biopsy was taken in all cases. The regrigerant used for cryosurgery was nitrous ox...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(78)90074-1

    authors： Popkin DR,Scali V,Ahmed MN

    更新日期：1978-03-01 00:00:00

  • HLA sharing and spontaneous abortion in humans.

    abstract：:Twenty-one Caucasian couples with two or more idiopathic fetal losses and with either no live-born children or with only one live-born child were typed for HLA-A, B, and DR antigens, and mixed lymphocyte responses of the maternal lymphocytes to stimulation by paternal lymphocytes were studied. The mixed lymphocyte res...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(85)90379-5

    authors： Thomas ML,Harger JH,Wagener DK,Rabin BS,Gill TJ 3rd

    更新日期：1985-04-15 00:00:00

  • Obstetrician-gynecologists performing genetic amniocentesis may be misleading themselves and their patients.

    abstract：OBJECTIVE:Our purpose was to compare midtrimester amniocentesis-related fetal loss rates between obstetrician-gynecologists and perinatologists. STUDY DESIGN:This cohort study analyzes 1384 midtrimester amniocenteses from January 1, 1996, to December 31, 1999. Obstetrician-gynecologists who split their practices betwe...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.115049

    authors： Blessed WB,Lacoste H,Welch RA

    更新日期：2001-06-01 00:00:00

  • Endometrial adenocarcinoma estrogen receptor content: association of clinicopathologic features with immunohistochemical analysis compared with standard biochemical methods.

    abstract：:Endometrial adenocarcinomas from 96 patients were studied for their biochemical estrogen receptor content as well as immunohistochemical localization of estrogen receptor. A well-characterized specific monoclonal antihuman estrogen receptor antibody (H222 sp gamma) as amplified by peroxidase/antiperoxidase techniques ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(87)80090-x

    authors： Mutch DG,Soper JT,Budwit-Novotny DA,Cox EB,Creasman WT,McCarty KS Sr,McCarty KS Jr

    更新日期：1987-10-01 00:00:00

  • Levator hiatus dimensions in late pregnancy and the process of labor: a 3- and 4-dimensional transperineal ultrasound study.

    abstract：OBJECTIVE:The objectives of the investigation were to study the association between levator hiatus dimensions in late pregnancy and both the length of second stage of labor and also the delivery mode in women delivering their first child. STUDY DESIGN:In this cohort study, 231 nulliparous women were examined with 3- a...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2014.02.021

    authors： Siafarikas F,Stær-Jensen J,Hilde G,Bø K,Ellström Engh M

    更新日期：2014-05-01 00:00:00

  • Doppler ultrasonography in obstetrics: from the diagnosis of fetal anemia to the treatment of intrauterine growth-restricted fetuses.

    abstract：:After the adoption of the use of umbilical artery and middle cerebral artery peak systolic velocity in high-risk pregnancies and in pregnancies that are at risk of having an anemic fetus, the main focus of Doppler ultrasonography in obstetrics today is intrauterine growth-restricted fetuses. What is most needed at thi...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2008.10.054

    authors： Mari G

    更新日期：2009-06-01 00:00:00