Abstract:
:This paper describes a methodology for achieving an efficient implementation of clinical practice guidelines. Three main steps are illustrated: knowledge representation, model simulation and implementation within a health care organisation. The resulting system can be classified as a 'guideline-based careflow management system'. It is based on computational formalisms representing both medical and health care organisational knowledge. This aggregation allows the implementation of a guideline, not only as a simple reminder, but also as an 'organiser' that facilitates health care processes. As a matter of fact, the system not only suggests the tasks to be performed, but also the resource allocation. The methodology initially comprehends a graphical editor, that allows an unambiguous representation of the guideline. Then the guideline is translated into a high-level Petri net. The resources, both human and technological necessary for performing guideline-based activities, are also represented by means of an organisational model. This allows the running of the Petri net for simulating the implementation of the guideline in the clinical setting. The purpose of the simulation is to validate the careflow model and to suggest the optimal resource allocation before the careflow system is installed. The final step is the careflow implementation. In this phase, we show that the 'workflow management' technology, widely used in business process automation, may be transferred to the health care setting. This requires augmenting the typical workflow management systems with the flexibility and the uncertainty management, typical of the health care processes. For illustrating the proposed methodology, we consider a guideline for the management of patients with acute ischemic stroke.
journal_name
Artif Intell Medjournal_title
Artificial intelligence in medicineauthors
Quaglini S,Stefanelli M,Cavallini A,Micieli G,Fassino C,Mossa Cdoi
10.1016/s0933-3657(00)00050-6subject
Has Abstractpub_date
2000-08-01 00:00:00pages
5-22issue
1eissn
0933-3657issn
1873-2860pii
S0933-3657(00)00050-6journal_volume
20pub_type
杂志文章abstract::This work presents a hybrid expert system (HES) intended to minimise some complex problems pervasive to knowledge engineering such as: the knowledge elicitation process, known as the bottleneck of expert systems; the choice of a model for knowledge representation to codify human reasoning; the number of neurons in the...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(00)00090-7
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:Brain-computer interfaces (BCIs) are no longer only used by healthy participants under controlled conditions in laboratory environments, but also by patients and end-users, controlling applications in their homes or clinics, without the BCI experts around. But are the technology and the field mature enough f...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.08.004
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Develop and evaluate a natural language processing application for classifying chief complaints into syndromic categories for syndromic surveillance. INTRODUCTION:Much of the input data for artificial intelligence applications in the medical field are free-text patient medical records, including dictated med...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.04.001
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:In this paper a new nonlinear system identification approach is developed for dynamical quantification of cardiovascular regulation. This approach is specifically focused on the identification of the heart rate (HR) baroreflex mechanism. The principal objective of this paper is to improve the model accuracy i...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.01.002
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To assess whether a user-centred prototype clinical decision support system (CDSS) providing patient-specific advice better supports healthcare practitioners in terms of (a) types of usability problems detected and (b) effective and efficient retrieval of childhood cancer survivor's follow-up screening proced...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.04.004
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:The aim of this paper is to study the feasibility and the performance of some classifier systems belonging to family of instance-based (IB) learning as second-opinion diagnostic tools and as tools for the knowledge extraction phase in the process of knowledge discovery in clinical databases. MATERIALS AND ME...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.04.002
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential knowledge, in their m...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.02.003
更新日期:2017-03-01 00:00:00
abstract::Pressure injuries represent a tremendous healthcare challenge in many nations. Elderly and disabled people are the most affected by this fast growing disease. Hence, an accurate diagnosis of pressure injuries is paramount for efficient treatment. The characteristics of these wounds are crucial indicators for the progr...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2019.101742
更新日期:2020-01-01 00:00:00
abstract::A new algorithm for neural network pruning is presented. Using this algorithm, networks with small number of connections and high accuracy rates for breast cancer diagnosis are obtained. We will then describe how rules can be extracted from a pruned network by considering only a finite number of hidden unit activation...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/0933-3657(95)00019-4
更新日期:1996-02-01 00:00:00
abstract::Problems involved in the specification of large expert systems are discussed. In the specification of causal probabilistic networks conditional probability tables for all nodes have to be provided. These conditional probability tables can often be described by models that specify the nature of interaction between node...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/0933-3657(93)90029-3
更新日期:1993-06-01 00:00:00
abstract::We created an inference engine and query language for expressing temporal patterns in data. The patterns are represented by using temporally-ordered sets of data objects. Patterns are elaborated by reference to new objects inferred from original data, and by interlocking temporal and other relationships among sets of ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/0933-3657(94)90066-3
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:This paper presents continued research toward the development of a knowledge-based system for the diagnosis of human toxic exposures. In particular, this research focuses on the challenging task of diagnosing exposures to multiple toxins. Although only 10% of toxic exposures in the United States involve multi...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.02.002
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:We address the task of inducing explanatory models from observations and knowledge about candidate biological processes, using the illustrative problem of modeling photosynthesis regulation. METHODS:We cast both models and background knowledge in terms of processes that interact to account for behavior. We a...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2006.04.003
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:Coronary artery disease has been described as one of the curses of the western world, as it is one of its most important causes of mortality. Therefore, clinicians seek to improve diagnostic procedures, especially those that allow them to reach reliable early diagnoses. In the clinical setting, coronary arter...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.04.009
更新日期:2011-06-01 00:00:00
abstract::The increasing access to brain signal data using electroencephalography creates new opportunities to study electrophysiological brain activity and perform ambulatory diagnoses of neurological disorders. This work proposes a pairwise distance learning approach for schizophrenia classification relying on the spectral pr...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2020.101852
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Arden Syntax is a standard for representing and sharing medical knowledge in form of independent modules and looks back on a history of 25 years. Its traditional field of application is the monitoring of clinical events such as generating an alert in case of occurrence of a critical laboratory result. Arden S...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2015.09.003
更新日期:2018-11-01 00:00:00
abstract::Rough sets (Pawlak Z. Rough Sets: Theoretical Aspects of Reasoning about Data, Dordrecht: Kluwer Academic Publishers, 1991) is a relatively new approach to representing and reasoning with incomplete and uncertain knowledge. This article introduces the basic concepts of rough sets and Boolean reasoning (Brown FM. Boole...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(98)00051-7
更新日期:1999-02-01 00:00:00
abstract:MOTIVATIONS:It has recently been argued [1] that the effectiveness of a cure depends on the doctor-patient shared understanding of an illness and its treatment. Although a better communication between doctor and patient can be pursued through dedicated training programs, or by collecting patients' experiences and sympt...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2019.101727
更新日期:2019-11-01 00:00:00
abstract::We describe an approach for developing knowledge-based medical decision support systems based on the new technology of case-based reasoning. This work is based on the results of the Inreca European project and preliminary results from the Inreca + project which mainly deals with medical applications. One goal was to s...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(97)00038-9
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:The Arden Syntax is a knowledge-encoding standard, started in 1989, and now in its 10th revision, maintained by the health level seven (HL7) organization. It has constructs borrowed from several language concepts that were available at that time (mainly the HELP hospital information system and the Regenstrie...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2015.11.003
更新日期:2018-11-01 00:00:00
abstract::As a crucial step of biological event extraction, event trigger identification has attracted much attention in recent years. Deep representation methods, which have the superiorities of less feature engineering and end-to-end training, show better performance than statistical methods. While most deep learning methods ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2019.101783
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:A major focus in computational system biology research is defining organizing principles that govern complex biological network formation and evolution. The task is considered a major challenge because network behavior and function prediction requires the identification of functionally and statistically impor...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2007.07.006
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:The radiology report is the most important source of clinical imaging information. It documents critical information about the patient's health and the radiologist's interpretation of medical findings. It also communicates information to the referring physicians and records that information for future clinic...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.artmed.2015.09.007
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:This work presents a system for a simultaneous non-invasive estimate of the blood glucose level (BGL) and the systolic (SBP) and diastolic (DBP) blood pressure, using a photoplethysmograph (PPG) and machine learning techniques. The method is independent of the person whose values are being measured and does n...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.05.001
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:This paper presents a novel rule-based fuzzy classification methodology for survival/mortality prediction in severe burnt patients. Due to the ethical aspects involved in this medical scenario, physicians tend not to accept a computer-based evaluation unless they understand why and how such a recommendation i...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.12.006
更新日期:2014-03-01 00:00:00
abstract::To explore the design of computer-supported collaborative work in health care, a case study is described addressing the social contexts and conditions influencing the development process. The data set covers 13 consecutive meetings held in a systems design group over a 2-year period, in total approximately 24 h of vid...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(97)00046-8
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:To use the detection of clinically relevant inconsistencies to support the reasoning capabilities of intelligent agents acting as physicians and tutors in the realm of clinical medicine. METHODS:We are developing a cognitive architecture, OntoAgent, that supports the creation and deployment of intelligent ag...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2012.04.005
更新日期:2012-07-01 00:00:00
abstract::Traditional Chinese medicine has developed over more than 4000 years. A tremendous amount of medical knowledge has been accumulated, among which herbal drugs and formulae are an important portion. This paper presents an ontology for traditional Chinese drugs and formulae, and an ontology-based system for extracting kn...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.01.015
更新日期:2004-09-01 00:00:00
abstract::Manual delineation of vestibular schwannoma (VS) by magnetic resonance (MR) imaging is required for diagnosis, radiosurgery dose planning, and follow-up tumor volume measurement. A rapid and objective automatic segmentation method is required, but problems have been encountered due to the low through-plane resolution ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2020.101911
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:Protein homology prediction between protein sequences is one of critical problems in computational biology. Such a complex classification problem is common in medical or biological information processing applications. How to build a model with superior generalization capability from training samples is an ess...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2005.02.003
更新日期:2005-09-01 00:00:00