Abstract：
:Although toxins exert their impact on a molecular level, they may yield molar effects by affecting areas large enough to be visualized by neuroimaging techniques. Therefore, neuroimaging of the brain may be used to render the macroscopic sequelae of neurotoxins visible. Toxic agents may induce brain edema or atrophy, demyelination, infarctions, calcifications, hemorrhages, or changes of perfusion, metabolism or receptor density. Although they do not readily disclose their nature, clues as to the offending agent may in some instances be gleaned from the pattern, distribution, and appearance of the cerebral changes. Intoxication, however, has always to be proved or substantiated independently by appropriate means. This paper deals with the extent and certainty to which conclusions as to some of the most common offending substances may be drawn from pictures of the brain.
journal_name
Neurotoxicologyjournal_title
Neurotoxicologyauthors
Lang CJsubject
Has Abstractpub_date
2000-10-01 00:00:00pages
847-55issue
5eissn
0161-813Xissn
1872-9711journal_volume
21pub_type
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