Abstract:
:The original article to which this Correction refers was published in Statistics in Medicine 2000 19(14): 1901-1914.
journal_name
Stat Medjournal_title
Statistics in medicineauthors
Edwardes MDdoi
10.1002/1097-0258(20001115)19:21<3017::aid-sim785>subject
Has Abstractpub_date
2000-11-15 00:00:00pages
3017issue
21eissn
0277-6715issn
1097-0258pii
10.1002/1097-0258(20001115)19:21<3017::AID-SIM785>journal_volume
19pub_type
杂志文章abstract::In the analysis of composite endpoints in a clinical trial, time to first event analysis techniques such as the logrank test and Cox proportional hazard test do not take into account the multiplicity, importance, and the severity of events in the composite endpoint. Several generalized pairwise comparison analysis met...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.8388
更新日期:2019-12-30 00:00:00
abstract::Regardless of whether a statistician believes in letting a data set speak for itself through nominal p-values or believes in strict alpha conservation, the interpretation of experiments which are negative for the primary endpoint but positive for secondary endpoints is the source of some angst. The purpose of this pap...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0258(20000330)19:6<767::aid-sim
更新日期:2000-03-30 00:00:00
abstract::We consider the use of the assurance method in clinical trial planning. In the assurance method, which is an alternative to a power calculation, we calculate the probability of a clinical trial resulting in a successful outcome, via eliciting a prior probability distribution about the relevant treatment effect. This i...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5916
更新日期:2014-01-15 00:00:00
abstract::The incremental life expectancy, defined as the difference in mean survival times between two treatment groups, is a crucial quantity of interest in cost-effectiveness analyses. Usually, this quantity is very difficult to estimate from censored survival data with a limited follow-up period. The paper develops estimati...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.6951
更新日期:2016-09-10 00:00:00
abstract::Timeliness of a public health surveillance system is one of its most important characteristics. The process of predicting the present situation using available incomplete information from surveillance systems has received the term nowcasting and has high public health interest. Generally in Europe, general practitione...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5670
更新日期:2013-07-10 00:00:00
abstract::In cancer clinical trials, patients often experience a recurrence of disease prior to the outcome of interest, overall survival. Additionally, for many cancers, there is a cured fraction of the population who will never experience a recurrence. There is often interest in how different covariates affect the probability...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.6056
更新日期:2014-05-10 00:00:00
abstract::We have used Monte Carlo methods to compare the type I error properties of the conditional and unconditional versions of the generalized t and the generalized rank-sum tests to those of the independent samples t and Wilcoxon rank-sum tests. Results showed inflated type I errors for the conditional generalized tests bu...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780110410
更新日期:1992-02-28 00:00:00
abstract::A Non-Parametric Maximum Likelihood approach to the estimation of relative risks in the context of disease mapping is discussed and a NPML approximation to conditional autoregressive models is proposed. NPML estimates have been compared to other proposed solutions (Maximum Likelihood via Monte Carlo Scoring, Hierarchi...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/1097-0258(20000915/30)19:17/18<2539::aid-s
更新日期:2000-09-15 00:00:00
abstract::We investigate population-averaged (PA) and cluster-specific (CS) associations for clustered binary logistic regression in the context of a longitudinal clinical trial that investigated the association between tooth-specific visual elastase kit results and periodontal disease progression within 26 weeks of follow-up. ...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780140407
更新日期:1995-02-28 00:00:00
abstract::Repeated cross-sectional samples are common in national surveys of health like the National Health Interview Survey (NHIS). Because population health outcomes generally evolve slowly, pooling data across years can improve the precision of current-year annual estimates of disease prevalence and other health outcomes. P...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.3897
更新日期:2011-02-28 00:00:00
abstract::In observational cohort studies we may wish to examine the associations between fixed patient characteristics and the longitudinal changes from baseline in a repeated outcome measure. Many biological and other outcome measures are known to be subject to measurement error and biological variation. In an initial analysi...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.3725
更新日期:2009-11-20 00:00:00
abstract::The power prior has been widely used in many applications covering a large number of disciplines. The power prior is intended to be an informative prior constructed from historical data. It has been used in clinical trials, genetics, health care, psychology, environmental health, engineering, economics, and business. ...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.6728
更新日期:2015-12-10 00:00:00
abstract::There are inconsistencies between the formulas for the variance of standardized mean difference (SMD) in the Cochrane Handbook for Systematic Reviews and the variance reported in other sources. Instead of the variance appropriate for the SMD of a crossover experiment, the Cochrane Handbook uses the variance appropriat...
journal_title:Statistics in medicine
pub_type: 信件
doi:10.1002/sim.8669
更新日期:2020-11-30 00:00:00
abstract::We investigated interobserver variation between three physician readers in the independent classification of chest radiographs from 1771 taconite workers for pneumoconiosis. We analysed variation with a general methodology for the analysis of categorical data, and quantified interobserver agreement in terms of kappa-t...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780030109
更新日期:1984-01-01 00:00:00
abstract::Confidence intervals for a standardized effect are derived after stabilizing the variance of the Welch t-statistic. Simulation studies demonstrate the viability of the resulting intervals for a wide range of parameter values and sample sizes as small as five. The methodology is extended to the combination of results f...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.2751
更新日期:2007-06-30 00:00:00
abstract::Technologic advances give rise to new tests for detecting disease in many fields, including cancer and sexually transmitted disease. Before a new disease screening test is approved for public use, its accuracy should be shown to be better than or at least not inferior to an existing test. Standards do not yet exist fo...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1058
更新日期:2002-03-30 00:00:00
abstract::Studies in health research are commonly carried out in clustered settings, where the individual response data are correlated within clusters. Estimation and modelling of the extent of between-cluster variation contributes to understanding of the current study and to design of future studies. It is common to express be...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.2304
更新日期:2006-05-15 00:00:00
abstract::The serial dilution assay (for example, an in vitro antimicrobic susceptibility test or a serum antibody titer assay) is an important technique in biomedical research. The structure of the experiment forces grouping of the threshold concentrations into intervals. Statistical methods to analyse threshold concentrations...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780070410
更新日期:1988-04-01 00:00:00
abstract::Systematic reviews often provide recommendations for further research. When meta-analyses are inconclusive, such recommendations typically argue for further studies to be conducted. However, the nature and amount of future research should depend on the nature and amount of the existing research. We propose a method ba...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5524
更新日期:2013-01-15 00:00:00
abstract::During phase III clinical trials in life-threatening disease settings, it is important to ensure that the Data Monitoring Committee (DMC) has exclusive access to the interim efficacy and safety data generated by the data analysis centre, in order to minimize the risk of widespread prejudgement of unreliable trial resu...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1288
更新日期:2002-10-15 00:00:00
abstract::Many split-mouth trials are characterized by the pairing of site-specific outcome and baseline data within each segment of a subject's mouth. However when the response variable of interest is binary, methods of statistical analysis for this design are not well developed. In this paper we present several analytic appro...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.2782
更新日期:2007-08-15 00:00:00
abstract::In natural history studies of chronic disease, it is of interest to understand the evolution of key variables that measure aspects of disease progression. This is particularly true for immunological variables among persons infected with the human immunodeficiency virus (HIV). The natural time scale for such studies is...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780131103
更新日期:1994-06-15 00:00:00
abstract::The stability-controlled quasi-experiment (SCQE) is an approach to study the effects of nonrandomized, newly adopted treatments. While covariate adjustment techniques rely on a "no unobserved confounding" assumption, SCQE imposes an assumption on the change in the average nontreatment outcome between successive cohort...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.8717
更新日期:2020-12-10 00:00:00
abstract::Bioequivalence or interaction trials are commonly studied in crossover design and can be analysed by nonlinear mixed effects models as an alternative to noncompartmental approach. We propose an extension of the population Fisher information matrix in nonlinear mixed effects models to design crossover pharmacokinetic t...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4390
更新日期:2012-05-20 00:00:00
abstract::For clinical trials with multiple treatment arms or endpoints a variety of sequentially rejective, weighted Bonferroni-type tests have been proposed, such as gatekeeping procedures, fixed sequence tests, and fallback procedures. They allow to map the difference in importance as well as the relationship between the var...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.3495
更新日期:2009-02-15 00:00:00
abstract::We examine Goodman and Kruskal's lambda using Efron's approach to regression and analysis of variance (ANOVA) for zero-one outcome data. For a binary response cross-classified by a single nominal predictor, we present a computationally simple ANOVA table in which lambda is analogous to Pearson's R-square. We character...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780080511
更新日期:1989-05-01 00:00:00
abstract::I discuss alternatives to the one compartment model, delta Yt = alpha + beta exp(- gamma t). Instead of comparing the one and two compartment models, I derive statistics for testing mixtures of the parameters (beta, gamma) in the one compartment model. I apply the proposed methods to the problem of hydrogen clearance ...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780080811
更新日期:1989-08-01 00:00:00
abstract::Case-control studies are prone to low power for testing gene-environment interactions (GXE) given the need for a sufficient number of individuals on each strata of disease, gene, and environment. We propose a new study design to increase power by strategically pooling biospecimens. Pooling biospecimens allows us to in...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5357
更新日期:2012-11-20 00:00:00
abstract::We estimate a Cox proportional hazards model where one of the covariates measures the level of a subject's cognitive functioning by grading the total score obtained by the subject on the items of a questionnaire. A case study is presented where the sample includes partial respondents, who did not answer some questionn...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.3773
更新日期:2010-01-30 00:00:00
abstract::We propose a two-step procedure to personalize drug dosage over time under the framework of a log-linear mixed-effect model. We model patients' heterogeneity using subject-specific random effects, which are treated as the realizations of an unspecified stochastic process. We extend the conditional quadratic inference ...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.7016
更新日期:2016-10-30 00:00:00