Comparison of risk factors for four sexually transmitted infections: results from a study of attenders at three genitourinary medicine clinics in England.

Abstract:

OBJECTIVE:To compare the risk factors for four common sexually transmitted infections (STIs) in attenders at three large urban genitourinary medicine (GUM) clinics in England. METHODS:Clinical, demographic, and behavioural data on attenders at two clinics in London and one in Sheffield were collected. Risk factors associated with first episodes of genital warts and genital herpes simplex virus (HSV), and uncomplicated gonorrhoea and chlamydia were investigated using the presence of each of these STIs as the outcome variable in separate multiple logistic regression analyses. RESULTS:Using data on the first attendance of the 18,238 patients attending the clinics in 1996, the risk of a gonorrhoea or chlamydia diagnosis was strongly associated with teenagers compared with those aged over 34, with black Caribbeans and black Africans compared with whites, and increased with the number of sexual partners. The risk of genital warts or HSV diagnosis was lowest in black Caribbeans and black Africans compared with whites and was not associated with the number of sexual partners. While genital warts were associated with younger age, odds ratios were much lower compared with those for the bacterial infections. Genital HSV diagnoses were not associated with age. CONCLUSIONS:This study of GUM clinic attenders suggests a reduction in the incidence of bacterial STIs may be achievable through targeted sexual health promotion focusing particularly on black ethnic minorities, teenagers, and those with multiple sexual partnerships. Viral STIs were less clearly associated with population subgroups and a broader population based approach to sexual health promotion may be more effective in controlling these infections.

journal_name

Sex Transm Infect

authors

Hughes G,Catchpole M,Rogers PA,Brady AR,Kinghorn G,Mercey D,Thin N

doi

10.1136/sti.76.4.262

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

262-7

issue

4

eissn

1368-4973

issn

1472-3263

journal_volume

76

pub_type

杂志文章
  • High-risk sexual behaviours among gay and bisexual men: comparing event-level casual sex encounters among seroconverters and non-seroconverters.

    abstract:BACKGROUND:With increasing use of non-condom-based HIV risk reduction strategies by gay and bisexual men (GBM), we compared occasions of condomless anal intercourse with casual partners (CLAIC) that resulted in HIV transmission and similar occasions when HIV transmission did not occur. METHODS:We compared two demograp...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2016-052749

    authors: Down I,Ellard J,Triffitt K,Zablotska I,Hurley M,Brown G,Bradley J,Prestage G

    更新日期:2017-08-01 00:00:00

  • HIV testing and self-reported HIV status in South African men who have sex with men: results from a community-based survey.

    abstract:OBJECTIVE:To investigate the characteristics of South African men who have sex with men (MSM) who (1) have been tested for HIV and (2) are HIV positive. METHODS:Data were collected from 1045 MSM in community surveys using questionnaires that were administered either face-to-face, by mail or on the internet. The mean a...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2008.031500

    authors: Sandfort TG,Nel J,Rich E,Reddy V,Yi H

    更新日期:2008-11-01 00:00:00

  • What is the excess risk of infertility in women after genital chlamydia infection? A systematic review of the evidence.

    abstract:OBJECTIVE:To summarise evidence on the attributable risk of infertility after chlamydial infection in women. METHODS:Twelve databases were searched, limited to peer-reviewed literature published from January 1970 to September 2007. Conference abstracts and reference lists from reviews published since 2000 and from key...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sti.2007.026047

    authors: Wallace LA,Scoular A,Hart G,Reid M,Wilson P,Goldberg DJ

    更新日期:2008-06-01 00:00:00

  • The performance of non-NAAT point-of-care (POC) tests and rapid NAAT tests for chlamydia and gonorrhoea infections. An assessment of currently available assays.

    abstract:OBJECTIVES:To identify point-of-care (POC) and rapid nucleic acid amplification techniques (NAATs) for the diagnosis of chlamydia and gonorrhoea and assess their utility. METHODS:Literature search for available POC and rapid NAATs. The performance from the best-performing assays were applied hypothetically to patients...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sextrans-2014-051997

    authors: Brook G

    更新日期:2015-12-01 00:00:00

  • Adenovirus urethritis and concurrent conjunctivitis: a case series and review of the literature.

    abstract::We present eight cases and review the literature of concurrent urethritis and conjunctivitis where adenovirus was identified as the causative pathogen. The focus of this review concerns the identification of specific sexual practices, symptoms, signs and any serotypes that seem more commonly associated with such adeno...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sextrans-2014-051868

    authors: Liddle OL,Samuel MI,Sudhanva M,Ellis J,Taylor C

    更新日期:2015-03-01 00:00:00

  • Assisting medical students to conduct empathic conversations with patients from a sexual medicine clinic.

    abstract:OBJECTIVE:To describe an exercise, the structure and content of which assists medical students to conduct potentially embarrassing conversations concerning sexual health which require expression of empathy, to integrate previous learning, to identify their further learning needs, and to develop and test strategies to m...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.4.246

    authors: Henderson P,Johnson MH

    更新日期:2002-08-01 00:00:00

  • Age-disparate partnerships and HSV-2 among adolescent girls and young women in South Africa: implications for HIV infection risk.

    abstract:OBJECTIVE:There is an urgent need to understand high HIV-infection rates among young women in sub-Saharan Africa. While age-disparate partnerships have been characterised with high-risk sexual behaviours, the mechanisms through which these partnerships may increase HIV-risk are not fully understood. This study assessed...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2018-053577

    authors: Maughan-Brown B,George G,Beckett S,Evans M,Lewis L,Cawood C,Khanyile D,Kharsany ABM

    更新日期:2019-09-01 00:00:00

  • An immunofiltration device for the simultaneous detection of non-treponemal and treponemal antibodies in patients with syphilis.

    abstract:OBJECTIVE:The development of a rapid immunofiltration (flow-through) test for the simultaneous detection of non-treponemal and treponemal antibodies in the serum of patients with syphilis. METHODS:The assay is rapid, inexpensive, and requires limited expertise in interpreting the results. The test is based on the prin...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.042937

    authors: Castro AR,Mody HC,Parab SY,Patel MT,Kikkert SE,Park MM,Ballard RC

    更新日期:2010-12-01 00:00:00

  • Condomless sex in HIV-diagnosed men who have sex with men in the UK: prevalence, correlates, and implications for HIV transmission.

    abstract:OBJECTIVE:HIV transmission is ongoing among men who have sex with men (MSM) in the UK. Sex without a condom (condomless sex, CLS) is the main risk factor. We investigated the prevalence of and factors associated with types of CLS. METHODS:Cross-sectional questionnaire study in UK HIV clinics in 2011/2012 (ASTRA). MSM ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sextrans-2016-053029

    authors: Daskalopoulou M,Rodger AJ,Phillips AN,Sherr L,Elford J,McDonnell J,Edwards S,Perry N,Wilkins E,Collins S,Johnson AM,Burman WJ,Speakman A,Lampe FC,ASTRA Study Group.

    更新日期:2017-12-01 00:00:00

  • Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial. DITRAME Study Group.

    abstract:OBJECTIVES:To study the tolerance and acceptability in Africa of a perinatal intervention to prevent vertical HIV transmission using benzalkonium chloride disinfection. DESIGN:A randomized, double blinded phase II trial. SETTING:Prenatal care units in Abidjan (Côte d'Ivoire) and Bobo-Dioulasso (Burkina Faso). PATIEN...

    journal_title:Sexually transmitted infections

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/sti.75.6.420

    authors: Msellati P,Meda N,Leroy V,Likikouët R,Van de Perre P,Cartoux M,Bonard D,Ouangre A,Combe P,Gautier-Charpentier L,Sylla-Koko F,Lassalle R,Dosso M,Welffens-Ekra C,Dabis F,Mandelbrot L

    更新日期:1999-12-01 00:00:00

  • Risk factors and pregnancy outcomes in women with syphilis diagnosed using a molecular approach.

    abstract:OBJECTIVES:To investigate the risk factors for infection and the outcome of pregnancy in women diagnosed with syphilis using a molecular approach. METHODS:Case-control study of pregnant women admitted to a maternity ward, with the cases classified as early or latent maternal syphilis, based on clinical-serological dia...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-050552

    authors: Casal C,Araújo Eda C,Corvelo TC

    更新日期:2013-05-01 00:00:00

  • Molecular epidemiological analysis of Mycoplasma genitalium shows low prevalence of azithromycin resistance and a well-established epidemic in South Africa.

    abstract:OBJECTIVES:Macrolide resistance in Mycoplasma genitalium is emerging globally. There is paucity of data from sub-Saharan Africa where syndromic management is used to treat sexually transmitted infections (STIs). We conducted a molecular epidemiological study to determine the prevalence of azithromycin resistance and ep...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2019-054371

    authors: Laumen JGE,van Alphen LB,Maduna LD,Hoffman CM,Klausner JD,Medina-Marino A,Kock MM,Peters RPH

    更新日期:2020-05-10 00:00:00

  • Chlamydia infection in individuals reporting contact with sexual partners with chlamydia: a cross-sectional study of sexual health clinic attendees.

    abstract:OBJECTIVES:We aimed to ascertain the proportion of positive, and predictive factors of chlamydia infection among females, heterosexual males and men who have sex with men (MSM) presenting to a sexual health service reporting contact with a chlamydia infected sexual partner. METHODS:A cross-sectional analysis of patien...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2015-052068

    authors: Huffam S,Chow EP,Fairley CK,Hocking J,Peel J,Chen M

    更新日期:2015-09-01 00:00:00

  • "A bit more truthful": the validity of adolescent sexual behaviour data collected in rural northern Tanzania using five methods.

    abstract:OBJECTIVE:To assess the validity of sexual behaviour data collected from African adolescents using five methods. METHODS:9280 Tanzanian adolescents participated in a biological marker and face to face questionnaire survey and 6079 in an assisted self-completion questionnaire survey; 74 participated in in-depth intervi...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2004.011924

    authors: Plummer ML,Ross DA,Wight D,Changalucha J,Mshana G,Wamoyi J,Todd J,Anemona A,Mosha FF,Obasi AI,Hayes RJ

    更新日期:2004-12-01 00:00:00

  • Anal HPV detection in men who have sex with men living with HIV who report no recent anal sexual behaviours: baseline analysis of the Anal Cancer Examination (ACE) study.

    abstract:OBJECTIVES:Men who have sex with men (MSM) living with HIV are at high risk of infection with high-risk human papillomavirus (HPV), the cause of anal cancer. We assess whether anal HPV DNA detection is related to recent anal sexual activity, what types of anal sexual activity or the persistence of HPV genotypes. METHO...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sextrans-2015-052121

    authors: Ong JJ,Chen M,Tabrizi SN,Cornall A,Garland SM,Jin F,Tee BK,Eu B,Fairley CK

    更新日期:2016-08-01 00:00:00

  • Is smoking tobacco an independent risk factor for HIV infection and progression to AIDS? A systemic review.

    abstract:OBJECTIVES:To systematically review the evidence of the relation between smoking tobacco and HIV seroconversion and progression to AIDS. METHODS:A systematic review was undertaken of studies to look at tobacco smoking as a risk factor for either HIV seroconversion or progression to AIDS. RESULTS:Six studies were iden...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sti.2005.019505

    authors: Furber AS,Maheswaran R,Newell JN,Carroll C

    更新日期:2007-02-01 00:00:00

  • Relative prevalence of different sexually transmitted infections in HIV-discordant sexual partnerships: data from a risk network study in a high-risk New York neighbourhood.

    abstract:OBJECTIVES:To determine infection patterns of sexually transmitted infections that facilitate HIV transmission among HIV-discordant couples. METHODS:112 initial respondents were recruited in an impoverished neighbourhood of Brooklyn, New York. Their sexual (and injection) partners were recruited in up to four addition...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2007.026815

    authors: Friedman SR,Bolyard M,Sandoval M,Mateu-Gelabert P,Maslow C,Zenilman J

    更新日期:2008-02-01 00:00:00

  • Awareness of post-exposure HIV prophylaxis in high-risk men who have sex with men in New York City.

    abstract:OBJECTIVES:To understand the factors associated with knowledge of non-occupational post-exposure prophylaxis (nPEP) and pre-exposure prophylaxis (PrEP), bathhouse patrons in New York City (NYC) were surveyed. METHODS:554 men who have sex with men (MSM) at two NYC bathhouses were given a standardised survey focused on ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.046284

    authors: Mehta SA,Silvera R,Bernstein K,Holzman RS,Aberg JA,Daskalakis DC

    更新日期:2011-06-01 00:00:00

  • Herpes simplex virus type 2: epidemiology and management options in developing countries.

    abstract::Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical disease and the occurrence of asymptomatic shedding. The lack of ea...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sti.2006.020966

    authors: Paz-Bailey G,Ramaswamy M,Hawkes SJ,Geretti AM

    更新日期:2007-02-01 00:00:00

  • Implications of current recommendations for third-generation cephalosporin use in the WHO Western Pacific Region following the emergence of multiresistant gonococci.

    abstract::To ascertain recommendations for the treatment of gonorrhoea in the WHO Western Pacific Region (WPR) following the emergence of "cephalosporin-resistant" Neisseria gonorrhoeae and to relate these to clinical and laboratory measures directed towards disease and antibiotic resistance control. WHO WPR Gonococcal Antimicr...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2008.035337

    authors: Tapsall JW

    更新日期:2009-08-01 00:00:00

  • Association of perceived partner non-monogamy with prevalent and incident sexual concurrency.

    abstract:OBJECTIVES:Concurrency is suggested as an important factor in sexually transmitted infection transmission and acquisition, though little is known regarding factors that may predict concurrency initiation. We examined the association between perception of a partner's non-monogamy (PPNM) and simultaneous or subsequent co...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2015-052111

    authors: Sanchez DM,Schoenbach VJ,Harvey SM,Warren JT,Adimora AA,Poole C,Leone PA,Agnew CR

    更新日期:2016-06-01 00:00:00

  • Screening for asymptomatic STIs in HIV-infected men who have sex with men.

    abstract::We aimed to study the prevalence, characteristics and risk factors of asymptomatic sexually transmitted infections (STIs) in HIV-infected men who have sex with men (MSM). We conducted a prospective cross-sectional study, including asymptomatic HIV-infected MSM attending regular visits between December 2014 and Decembe...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2020-054560

    authors: Willekens R,Sánchez I,Miguel L,Esperalba J,Serra-Pladevall J,Martin M,Navarro J,Falcó V,Burgos J,Ribera E,Caballero E,Curran A

    更新日期:2020-08-04 00:00:00

  • Trends in gonorrhoea positivity by nucleic acid amplification test versus culture among Australian heterosexual men with a low prevalence of gonorrhoea, 2007-2014.

    abstract:BACKGROUND:Testing for gonorrhoea with nucleic acid amplification tests (NAATs) is not recommended in low-prevalence populations as it results in high numbers of false positive results. The aim of this study was to examine temporal trends of gonorrhoea positivity by NAAT and culture in heterosexual men in Victoria, Aus...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2015-052246

    authors: Mannion PK,Fairley CK,Fehler G,Tabrizi SN,Tan WS,Chen MY,Bradshaw CS,Chow EP

    更新日期:2016-12-01 00:00:00

  • The effects of scale on the costs of targeted HIV prevention interventions among female and male sex workers, men who have sex with men and transgenders in India.

    abstract:BACKGROUND:The India AIDS Initiative (Avahan) project is involved in rapid scale-up of HIV-prevention interventions in high-risk populations. This study examines the cost variation of 107 non-governmental organisations (NGOs) implementing targeted interventions, over the start up (defined as period from project incepti...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2009.038547

    authors: Chandrashekar S,Guinness L,Kumaranayake L,Reddy B,Govindraj Y,Vickerman P,Alary M

    更新日期:2010-02-01 00:00:00

  • Sexual behaviour and early coitarche in a national sample of 17 year old Swedish girls.

    abstract:OBJECTIVE:To evaluate sexual behaviour in 17 year old girls, using data from a national survey on adolescent sexuality. METHOD:The study was based on two samples of 17 year olds, comprising 2% of the population born in 1973 and carried out in 1990. A school sample and a sample of school non-attenders were recruited in...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.76.2.98

    authors: Edgardh K

    更新日期:2000-04-01 00:00:00

  • Distinct HIV discordancy patterns by epidemic size in stable sexual partnerships in sub-Saharan Africa.

    abstract:OBJECTIVE:To describe patterns of HIV infection among stable sexual partnerships across sub-Saharan Africa (SSA). METHODS:The authors defined measures of HIV discordancy and conducted a comprehensive quantitative assessment of discordancy among stable partnerships in 20 countries in SSA through an analysis of the Demo...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sextrans-2011-050114

    authors: Chemaitelly H,Cremin I,Shelton J,Hallett TB,Abu-Raddad LJ

    更新日期:2012-02-01 00:00:00

  • Inequalities in access to genitourinary medicine clinics in the UK: results from a mystery shopper survey.

    abstract:STUDY DESIGN:This study investigated whether access to genitourinary medicine (GUM) clinics meets UK-recommended standards. METHODS:In January 2014 and 2015, postal questionnaires about appointment and service characteristics were sent to lead clinicians of UK GUM clinics. In February 2014 and 2015, researchers posing...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2016-052882

    authors: Foley E,Furegato M,Hughes G,Board C,Hayden V,Prescott T,Shone E,Patel R

    更新日期:2017-11-01 00:00:00

  • Diagnosis of sexually transmitted infections in female prostitutes in Dakar, Senegal.

    abstract:OBJECTIVE:To study the validity and performance of a number of rapid indicators for the diagnosis of sexually transmitted infections (STIs) in female prostitutes in Dakar, Senegal; characteristics of these indicators were rapidly obtainable, easy to perform, accurate, useful at district level, and reasonable cost. MET...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:

    authors: Ndoye I,Mboup S,De Schryver A,Van Dyck E,Moran J,Samb ND,Sakho ML,Thior I,Wade A,Heymann DL,Meheus A

    更新日期:1998-06-01 00:00:00

  • Prevalence and factors associated with HSV-2 and hepatitis B infections among truck drivers crossing the southern Brazilian border.

    abstract:OBJECTIVES:The authors estimate the prevalence of HIV, syphilis, hepatitis B virus (HBV) and herpes simplex virus type-2 (HSV-2) infection and correlates of HBV and HSV-2 infection among truck drivers crossing the southern Brazilian border at Foz do Iguaçu. METHODS:Between October 2003 and March 2005, 1945 truck drive...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2011-050186

    authors: Pinho AA,Chinaglia M,Lippman SA,Reingold A,Diaz RS,Sucupira MC,Page K,Díaz J

    更新日期:2011-12-01 00:00:00

  • Self-administered interventions for anogenital warts in immunocompetent patients: a systematic review and meta-analysis.

    abstract:BACKGROUND:Anogenital warts (AGWs, condylomata acuminata) are among the most common STIs and may severely impact quality of life (QoL). Available treatment options are characterised by a high proportion of non-responders and recurrences. OBJECTIVE:To systematically review and meta-analyse the available evidence from r...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,meta分析,评审

    doi:10.1136/sextrans-2016-052768

    authors: Werner RN,Westfechtel L,Dressler C,Nast A

    更新日期:2017-05-01 00:00:00