Human pancreatic ribonuclease 1: expression and distribution in pancreatic adenocarcinoma.

abstract：:Forty seven patients with early gastric cancer received a 30-minute intravenous injection of bromodeoxyuridine (BrdU), 1000 mg each 1 hour before laparotomy, to label tumor cells in the S phase. In 13 of 47 patients, specimens obtained by endoscopic biopsy were cultured in vitro at 37 degrees C for 1 hour under three ...

journal_title：Cancer

authors： Kamata T,Yonemura Y,Sugiyama K,Ooyama S,Kosaka T,Yamaguchi A,Miwa K,Miyazaki I

更新日期：1989-10-15 00:00:00

abstract：:The activity of the alpha interferons against AIDS-related Kaposi's sarcoma (KS) has been demonstrated in numerous clinical trials. Unfortunately, most reports have involved small patient cohorts and a variety of dosages and schedules of administration. We report here a series of Phase II trials with interferon alfa-2...

journal_title：Cancer

authors： Volberding PA,Mitsuyasu RT,Golando JP,Spiegel RJ

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Since endoscopic treatment was first evaluated and established as a treatment for patients with early stage gastric carcinoma, metachronous disease recurrence at other sites in the stomach after endoscopic treatment has become a major problem. METHODS:A retrospective case-control study was conducted on 10 p...

journal_title：Cancer

authors： Kawamura A,Adachi K,Ishihara S,Katsube T,Takashima T,Yuki M,Amano K,Fukuda R,Yamashita Y,Kinoshita Y

更新日期：2001-01-15 00:00:00

abstract：BACKGROUND:As we approach the 21st century, clinically useful predictive models for prostate carcinoma are urgently needed to stratify patients reliably for future treatment strategies. Recently, many investigators have developed models that employ prostate specific antigen (PSA)-based constructs or groupings in an att...

journal_title：Cancer

authors： Movsas B,Hanlon AL,Teshima T,Hanks GE

更新日期：1997-09-15 00:00:00

abstract：:A case is presented of a man with ulcerating skin nodules who was diagnosed by histologic and immunohistologic analysis of skin biopsy specimens as having lymphomatoid granulomatosis (LYG). Phenotypic studies showed the majority of the infiltrating cells to be activated CD4+ T-lymphocytes. The disease followed a rapid...

journal_title：Cancer

authors： Atkinson CH,Davis AL,Colls BM,Wolever TH,Burry AF,Hart DN

更新日期：1989-02-15 00:00:00

abstract：:The metabolism of 5-fluorouracil (5-FU) was studied in biopsy specimens of primary colorectal cancer and healthy colonic mucosa obtained from previously untreated patients immediately after surgical removal. The conversion of 5-FU to anabolites was measured under saturating substrate (5-FU) and cosubstrate concentrati...

journal_title：Cancer

authors： Peters GJ,van Groeningen CJ,Laurensse EJ,Pinedo HM

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Rising health care costs have caused providers to question the benefit of regular follow-up after treatment for patients with early stage cutaneous melanoma. The authors hypothesized that routine reassessment and careful education of these patients would facilitate earlier diagnosis of a subsequent second pr...

journal_title：Cancer

authors： DiFronzo LA,Wanek LA,Morton DL

更新日期：2001-04-15 00:00:00

abstract：BACKGROUND:The association of increasing radiotherapy (RT) dose with reduced biochemical failure (BF) is accepted widely. However, there is little direct evidence that dose escalation has an impact on distant metastasis (DM) or overall mortality (OM). These associations were examined in the current study. METHODS:The ...

journal_title：Cancer

authors： Jacob R,Hanlon AL,Horwitz EM,Movsas B,Uzzo RG,Pollack A

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Adjuvant radiation has been proposed for the treatment of patients with desmoplastic melanoma, who reportedly have local recurrence rates as high as 40-60%. The authors investigated local recurrence rates at a tertiary referral center to determine the success of wide excision alone for patients with desmopla...

journal_title：Cancer

authors： Arora A,Lowe L,Su L,Rees R,Bradford C,Cimmino VC,Chang AE,Johnson TM,Sabel MS

更新日期：2005-10-01 00:00:00

abstract：:Chlorozotocin was administered by rapid intravenous infusion to 35 patients with advanced cancer on either single-day of five-consecutive-day schedules. Total doses per course ranged from 12.5 to 200 mg/m2. On either administration schedule, dose limiting toxicities were thrombocytopenia and leukopenia at total doses ...

journal_title：Cancer

authors： Kovach JS,Moertel CG,Schutt AJ,Frytak S,O'Connell MJ,Rubin J,Ingle JN

更新日期：1979-06-01 00:00:00

abstract：:The serious import of breast cancer lies in its potential for metastatic spread, which probably starts early in the course of the disease. Detection of the lesion when immunocompetence can control the metastases leads to long-term survival. This usually involves detection of unsuspected, preclinical disease. This is t...

journal_title：Cancer

authors： Strax P

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：:Lymphocyte cyclic nucleotide content was studied before and after Levamisole administration to cancer patients. Twelve patients with disseminated cancer received 100 mg/m2 on two consecutive days; nine comparable patients with disseminated cancer served as controls. Endogenous cyclic adenosine monophosphate (cAMP) and...

journal_title：Cancer

authors： Lewinski UH,Mavligit GM,Thompson WJ,Hersh EM,Ortez RA

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Stomach cancer was a leading cause of cancer-related deaths early in the 20th century and has steadily declined over the last century in the United States. Although incidence and death rates are now low, stomach cancer remains an important cause of morbidity and mortality in black, Asian and Pacific Islander...

journal_title：Cancer

authors： Jim MA,Pinheiro PS,Carreira H,Espey DK,Wiggins CL,Weir HK

更新日期：2017-12-15 00:00:00

abstract：:Chemokines are chemoattractant cytokines that regulate the trafficking and activation of leukocytes and other cell types under a variety of inflammatory and noninflammatory conditions. Over the past few years, studies have increasingly shown that chemokines play an important role in several aspects of tumor progressio...

journal_title：Cancer

authors： Ruffini PA,Morandi P,Cabioglu N,Altundag K,Cristofanilli M

更新日期：2007-06-15 00:00:00

abstract：:The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various ...

journal_title：Cancer

authors： Tormey DC

更新日期：1975-09-01 00:00:00

abstract：:During recent years there has been a growing awareness among both the oncologic and nutrition communities about an association between nutrition and cancer causation with the practical implication of manipulating nutrition as a means of preventing cancer. Epidemiologic correlations, prospective studies of selected pop...

journal_title：Cancer

authors： Newell GR

更新日期：1983-06-15 00:00:00

abstract：BACKGROUND:In the current study, the authors propose the quantitative Gleason score (qGS), a modification of the current Gleason grading system for prostate cancer, based on the weighted average of Gleason patterns present in the pathology specimen. They hypothesize that the qGS can improve prostate cancer risk stratif...

journal_title：Cancer

authors： Reese AC,Cowan JE,Brajtbord JS,Harris CR,Carroll PR,Cooperberg MR

更新日期：2012-12-15 00:00:00

abstract：:If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic sp...

journal_title：Cancer

authors： Papillon J

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:The current study evaluated whether the risk of developing thyroid cancer in Asian women was associated with infertility and the use of fertility drugs. METHODS:The authors conducted a large, retrospective cohort study using Taiwan's National Health Insurance Research Database. From the insurance claims dat...

journal_title：Cancer

authors： Ding DC,Chen W,Wang JH,Lin SZ,Sung FC

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...

journal_title：Cancer

authors： Morrow M,Mujahid M,Lantz PM,Janz NK,Fagerlin A,Schwartz K,Liu L,Deapen D,Salem B,Lakhani I,Katz SJ

更新日期：2005-12-01 00:00:00

abstract：:To investigate the possible implications of heterogeneity among the non-Hodgkin's lymphomas for bone marrow purging using complement-fixing monoclonal antibodies to lymphoma-associated antigens, a panel of large cell lymphoma cell lines of diverse phenotypes was treated with monoclonal antibodies DLC-48 and LN-1. An a...

journal_title：Cancer

authors： Winter JN,Marder RJ,Mankad B,Epstein AL

更新日期：1988-03-15 00:00:00

abstract：:A case of bronchial mucoepidermoid carcinoma is reported, the presentation of which was as cutaneous metastases. Histologic, histochemical, and ultrastructural features of the neoplasm are described, and the literature pertaining to bronchial mucoepidermoid carcinoma is reviewed. This case illustrates the potential fo...

journal_title：Cancer

authors： Metcalf JS,Maize JC,Shaw EB

更新日期：1986-12-01 00:00:00

abstract：:Flow cytometry was used to compare binding of wheat germ agglutinin (WGA) and Lens culinaris lectin (Lcl) to peripheral lymphocytes (PBL) from normal subjects and 26 patients with chronic lymphocytic leukemia (CLL). As defined by the interactions of WGA and Lcl with cell surface receptors, normal unfractionated PBL an...

journal_title：Cancer

authors： Boldt DH,Nelson MO

更新日期：1983-06-01 00:00:00

abstract：:Canada is a westernized, market-economy nation with a publicly funded health care and cancer control system and has health indices reflective of a high-resource economy. Provision of health services is in accord with the Canada Health Act and is implemented through federal, provincial, and territorial relations wherei...

journal_title：Cancer

authors： Sutcliffe SB

更新日期：2011-05-15 00:00:00

abstract：BACKGROUND:Multidisciplinary management of head and neck cancer (HNC) must reconcile increasingly sophisticated subspecialty care with timeliness of care. Prior studies examined the individual effects of delays in diagnosis-to-treatment interval, postoperative interval, and radiation interval but did not consider them ...

journal_title：Cancer

authors： Ho AS,Kim S,Tighiouart M,Mita A,Scher KS,Epstein JB,Laury A,Prasad R,Ali N,Patio C,Clair JM,Zumsteg ZS

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:To assess the ability of [(18)F]fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET) to predict the viability of residual masses after chemotherapy in patients with metastatic nonseminomatous germ cell tumors (GCT), PET results were compared in a blinded analysis with computed tomography (CT) sca...

journal_title：Cancer

authors： Kollmannsberger C,Oechsle K,Dohmen BM,Pfannenberg A,Bares R,Claussen CD,Kanz L,Bokemeyer C

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Alveolar soft part sarcoma (ASPS), chondrosarcoma (CS), chordoma, epithelioid sarcoma, and solitary fibrous tumor (SFT) are malignant tumors that are relatively resistant to chemotherapy and for which more effective drug therapy is needed. METHODS:The 5 listed subtypes were enrolled into a single indolent s...

journal_title：Cancer

authors： Schuetze SM,Bolejack V,Choy E,Ganjoo KN,Staddon AP,Chow WA,Tawbi HA,Samuels BL,Patel SR,von Mehren M,D'Amato G,Leu KM,Loeb DM,Forscher CA,Milhem MM,Rushing DA,Lucas DR,Chugh R,Reinke DK,Baker LH

更新日期：2017-01-01 00:00:00

abstract：:Findings from 1665 women with primary breast cancer, treated at 34 NSABP institutions in Canada and the United States, have failed to demonstrate that patients with medial-central tumors had a greater probability of developing distant metastases or dying than did those with lateral tumors despite the greater incidence...

journal_title：Cancer

authors： Fisher B,Wolmark N,Redmond C,Deutsch M,Fisher ER

更新日期：1981-10-15 00:00:00

abstract：BACKGROUND:The reliability of fine-needle aspiration cytology (FNAC) of breast masses in males could be compromised by lack of experience because breast carcinoma is rare in males and FNAC is not often used. In addition, FNAC of the more often encountered gynecomastia may lead to overdiagnosis. Therefore, in the curren...

journal_title：Cancer

authors： Westenend PJ,Jobse C

更新日期：2002-04-25 00:00:00