Use of radionuclide imaging in the early diagnosis and treatment of renal allograft rejection.

Abstract:

:Data are presented on the clinical application of radionuclide imaging to evaluate changes in cadaver transplant function in the immediate postoperative period. The method uses orthoiodohippuric acid (hippuran) administered IV, with scintillation imaging, and curve analysis by a digital computer. An initial study is always obtained 24 hours after transplantation. Serial studies are then obtained, as needed, to interpret the clinical course. Selected cases are presented which illustrate the use of this protocol in various clinical settings. In the oliguric patient serial studies have been of particular value. They have identified ATN so that over-enthusiastic treatment for rejection could be avoided. They have also identified acute rejection complicating ATN so that high dose steroid therapy could be administered appropriately. In the non-oliguric patient they have frequently contributed to the early diagnosis of acute rejection, and they have been useful in monitoring the effect and duration of treatment for severe rejection crisis. It is concluded that radionuclide imaging studies, when carefully applied and interpreted, are a valuable adjunct to the management of patients in this complex clinical setting.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Mandel SR,Mattern WD,Staab E,Johnson G Jr

doi

10.1097/00000658-197505000-00013

subject

Has Abstract

pub_date

1975-05-01 00:00:00

pages

596-603

issue

5

eissn

0003-4932

issn

1528-1140

journal_volume

181

pub_type

杂志文章
  • Accelerated partial breast irradiation after conservative surgery for breast cancer.

    abstract:OBJECTIVE:To critically review the theoretical and actual risks and benefits of accelerated partial breast irradiation (APBI) after breast-conserving surgery. SUMMARY BACKGROUND DATA:Because of rapid evolution of radiation therapy techniques related to brachytherapy and three-dimensional conformal radiation therapy, A...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/01.sla.0000114219.71899.13

    authors: Kuerer HM,Julian TB,Strom EA,Lyerly HK,Giuliano AE,Mamounas EP,Vicini FA

    更新日期:2004-03-01 00:00:00

  • The endorectal pull-through for the management of ulcerative colitis in children and adults.

    abstract::Between June 1977 and November 1981, 26 children and adults with ulcerative colitis have undergone a total colectomy, an endorectal dissection of the rectal mucosa, and an ileoanostomy. A combined abdominoperineal approach was used to perform the operation, and the mucosal-submucosal rectal tube was dissected out inta...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:

    authors: Coran AG,Sarahan TM,Dent TL,Fiddian-Green R,Wesley JR,Jordan FT

    更新日期:1983-01-01 00:00:00

  • Percutaneous transhepatic bile drainage.

    abstract::Percutaneous transhepatic bile drainage was performed in 13 patients with obstructive jaundice, using a combination of the PTC technique and a Seldinger angiography catheter. In 11 cases, the outflow of bile through the catheter was satisfactory and complications were few. Since the risk of the procedure is low and it...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197701000-00018

    authors: Mori K,Misumi A,Sugiyama M,Okabe M,Matsuoka T

    更新日期:1977-01-01 00:00:00

  • Surgery, trauma and immune suppression. Evolving the mechanism.

    abstract::A major surgical procedure can impair the delayed hypersensitivity response. This impairment is associated with suppressor cell activity that can alter either afferent or efferent responses. Using the third party mixed leukocyte culture to define cell types involved, major immune impairment was seen with the combinati...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198304000-00010

    authors: Lundy J,Ford CM

    更新日期:1983-04-01 00:00:00

  • Surgical management of bleeding chronic peptic ulcer. A 10-year prospective study.

    abstract::Analysis of experience with chronic bleeding peptic ulcer in 504 patients, admitted from 1960 to 1971, shows a hospital mortality of 12%. This retrospective review suggested that early endoscopic diagnosis, adequate resuscitation and a policy of early selective surgery was necessary if mortality was to be reduced. Wit...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198401000-00008

    authors: Hunt PS

    更新日期:1984-01-01 00:00:00

  • Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study.

    abstract:OBJECTIVE:To prospectively characterize changes in body weight, satiety, and postprandial gut hormone profiles following esophagectomy. BACKGROUND:With improved oncologic outcomes in esophageal cancer, there is an increasing focus on functional status and health-related quality of life in survivorship. Early satiety a...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001918

    authors: Elliott JA,Docherty NG,Eckhardt HG,Doyle SL,Guinan EM,Ravi N,Reynolds JV,Roux CWL

    更新日期:2017-07-01 00:00:00

  • Clinical significance of the mesorectal extension of rectal cancer: a Japanese multi-institutional study.

    abstract:OBJECTIVE:The aim of this study was to emphasize the importance of a subclassification in the TNM staging system of rectal cancer. BACKGROUND:The clinical significance of the mesorectal extension of rectal cancer is unclear. PATIENTS AND METHODS:Data from 463 consecutive patients with stage IIa disease (T3N0) undergo...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0b013e3182119331

    authors: Shirouzu K,Akagi Y,Fujita S,Ueno H,Takii Y,Komori K,Ito M,Sugihara K,Japanese Society for Cancer of the Colon and Rectum (JSCCR) on Clinical Significance of the Mesorectal Extension of Rectal Cancer.

    更新日期:2011-04-01 00:00:00

  • Hilar cholangiocarcinoma: current management.

    abstract:OBJECTIVE:To review the literature with regard to outcome of surgical management for hilar cholangiocarcinoma (Klatskin tumor). BACKGROUND:Hilar cholangiocarcinoma is a rare tumor with a poor prognosis. Surgical resection provides the only possibility for cure. Advances in hepatobiliary imaging and surgical strategies...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SLA.0b013e3181afe0ab

    authors: Ito F,Cho CS,Rikkers LF,Weber SM

    更新日期:2009-08-01 00:00:00

  • Lymph node retrieval during esophagectomy with and without neoadjuvant chemoradiotherapy: prognostic and therapeutic impact on survival.

    abstract:OBJECTIVES:We aimed to examine the association between total number of resected nodes and survival in patients after esophagectomy with and without nCRT. BACKGROUND:Most studies concerning the potentially positive effect of extended lymphadenectomy on survival have been performed in patients who underwent surgery alon...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000000965

    authors: Koen Talsma A,Shapiro J,Looman CW,van Hagen P,Steyerberg EW,van der Gaast A,van Berge Henegouwen MI,Wijnhoven BP,van Lanschot JJ,CROSS Study Group.,Hulshof MC,van Laarhoven HW,Nieuwenhuijzen GA,Hospers GA,Bonenkamp JJ,Cuest

    更新日期:2014-11-01 00:00:00

  • Twenty-five-year follow-up for liver resection: the personal series of Dr. Joseph G. Fortner.

    abstract:BACKGROUND:Liver resection is performed for many types of malignancies. Few reports document actual long-term survival. METHODS:Long-term follow-up of a series of 548 liver resections performed between 1970 and 1992 was performed and is presented. RESULTS:All patients were followed for at least 15 years after surgery...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181b59491

    authors: Fortner JG,Fong Y

    更新日期:2009-12-01 00:00:00

  • Evolution of the modified Rossetti fundoplication in children: surgical technique and results.

    abstract:OBJECTIVE:To compare the modified Rossetti fundoplication with the classic Nissen. SUMMARY BACKGROUND DATA:The traditional surgical treatment of gastroesophageal reflux in children has been the classic Nissen fundoplication, defined by liver mobilization, crural repair, takedown of short gastric vessels, and floppy wr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199906000-00003

    authors: Levy MS,Sorrels CW,Wagner CW,Jackson RJ,Barnes RW,Smith SD

    更新日期:1999-06-01 00:00:00

  • Gastrocolic fistulae in benign peptic ulcer disease.

    abstract::Occurence of gastroenteric fistulae in non-surgically treated peptic ulcer disease is rare as suggested by only 26 cases published in the literature so far. We had the opportunity to care for 3 patients with this problem in a period of one year. At our institution, a search of the medical records dating back to 1955 y...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197608000-00017

    authors: Kumar GK,Razzaque MA,Naidu VG,Barbour EM

    更新日期:1976-08-01 00:00:00

  • Three-year follow-up of a prospective randomized trial comparing laparoscopic versus open gastric bypass.

    abstract:OBJECTIVE:To analyze long-term weight loss, changes in comorbidities and quality of life, and late complications after laparoscopic and open gastric bypass. SUMMARY BACKGROUND DATA:Early results from our prospective randomized trial comparing the outcome of laparoscopic versus open gastric bypass demonstrated less pos...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.sla.0000197381.01214.76

    authors: Puzziferri N,Austrheim-Smith IT,Wolfe BM,Wilson SE,Nguyen NT

    更新日期:2006-02-01 00:00:00

  • Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock.

    abstract:OBJECTIVE:To evaluate (1) levels of the host-defense/antimicrobial peptide LL-37 in patients with trauma and hemorrhagic shock (HS) and (2) the effects of a synthetic host-defense peptide; Pep19-4LF on multiple organ failure (MOF) associated with HS. BACKGROUND:HS is a common cause of death in severely injured patient...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002186

    authors: Yamada N,Martin LB,Zechendorf E,Purvis GSD,Chiazza F,Varrone B,Collino M,Shepherd J,Heinbockel L,Gutsmann T,Correa W,Brandenburg K,Marx G,Schuerholz T,Brohi K,Thiemermann C

    更新日期:2018-08-01 00:00:00

  • When Do DCD Donors Die?: Outcomes and Implications of DCD at a High-volume, Single-center OPO in the United States.

    abstract:OBJECTIVE:The objective of this study was to determine the fate of patients who attempted to donate organs after circulatory death (DCD) using a standardized DCD protocol. BACKGROUND:Successful donation is not always possible after attempted DCD. METHODS:Data were collected for all DCD donors between 1/2011 and 9/201...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001298

    authors: Scalea JR,Redfield RR,Rizzari MD,Bennett R,Anderson ME,Anderson JE,Kaufman DB,Sollinger HW,Fernandez LA,D'Alessandro AM,Mezrich J

    更新日期:2016-02-01 00:00:00

  • Common bile duct and Oddi sphincter pressure before and after endoscopic papillotomy in patients with common bile duct stones.

    abstract::Pressures in the Oddi sphincter and common bile duct were determined before, immediately after and several weeks after endoscopic papillotomy. Fifteen patients were included in the study. Significant decreases in Oddi sphincter and common bile duct pressures were found and the decrease in Oddi sphincter pressure was t...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197908000-00009

    authors: Funch-Jensen P,Csendes A,Kruse A,Oster MJ,Amdrup E

    更新日期:1979-08-01 00:00:00

  • Neurokinin-2 receptor levels correlate with intensity, frequency, and duration of pain in chronic pancreatitis.

    abstract:OBJECTIVE:Generation and maintenance of pain in chronic pancreatitis (CP) have been shown to be partially attributable to neuroimmune interactions, which involve neuropeptides such as substance P (SP). So far, expression of SP receptors NK-2R, NK-3R, the SP-encoding gene preprotachykinin A (PPT-A), and the SP degradati...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e318070d56e

    authors: Michalski CW,Shi X,Reiser C,Fachinger P,Zimmermann A,Büchler MW,Di Sebastiano P,Friess H

    更新日期:2007-11-01 00:00:00

  • Pylorus Resection Does Not Reduce Delayed Gastric Emptying After Partial Pancreatoduodenectomy: A Blinded Randomized Controlled Trial (PROPP Study, DRKS00004191).

    abstract:OBJECTIVES:The aim of this study was to investigate the effect of pylorus resection on postoperative delayed gastric emptying (DGE) after partial pancreatoduodenectomy (PD). BACKGROUND:PD is the standard treatment for tumors of the pancreatic head. Preservation of the pylorus has been widely accepted as standard proce...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000002480

    authors: Hackert T,Probst P,Knebel P,Doerr-Harim C,Bruckner T,Klaiber U,Werner J,Schneider L,Michalski CW,Strobel O,Ulrich A,Diener MK,Büchler MW

    更新日期:2018-06-01 00:00:00

  • The inhibition of aldose reductase attenuates hepatic ischemia-reperfusion injury through reducing inflammatory response.

    abstract:OBJECTIVE:We aim to investigate the role of aldose reductase (AR) in hepatic ischemia-reperfusion injury (IRI) of normal and fatty livers and to explore the underlying mechanisms. BACKGROUND:Hepatic IRI is a typical inflammatory response during liver surgery. It contributes to liver graft failure or nonfunction after ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000000429

    authors: Li CX,Ng KT,Shao Y,Liu XB,Ling CC,Ma YY,Geng W,Qi X,Cheng Q,Chung SK,Lo CM,Man K

    更新日期:2014-08-01 00:00:00

  • Management of combined pancreatoduodenal injuries.

    abstract::From 1969 to 1985, 129 patients with combined pancreatoduodenal injuries were treated at one urban trauma center. A total of 104 patients (80.6%) had penetrating wounds, and multiple visceral and vascular injuries were usually associated with the pancreatoduodenal injury. Primary repair or resection of one or both org...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198706000-00009

    authors: Feliciano DV,Martin TD,Cruse PA,Graham JM,Burch JM,Mattox KL,Bitondo CG,Jordan GL Jr

    更新日期:1987-06-01 00:00:00

  • Surgical management of reflux strictures of the esophagus in childhood.

    abstract::The etiology of gastroesophageal reflux (GER) in infancy is related to developmental factors, and there is a high incidence of associated conditions such as neurologic syndromes and esophageal atresia (60%). This is different from the situation in adults. Experience with 18 consecutive children with peptic esophageal ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198210000-00008

    authors: O'Neill JA Jr,Betts J,Ziegler MM,Schnaufer L,Bishop HC,Templeton JM

    更新日期:1982-10-01 00:00:00

  • The reservoir ileostomy: early experience with 54 patients.

    abstract::Reservoir and ileostomies were performed in 54 patients between 1972 and 1975. Primary colonic pathology included chronic ulcerative colitis in 47 patients, Crohn's colitis in one, familial polyposes in 5 and Gardner's Syndrome in one. Followup is complete and varies from 6 months to three years. All but three patient...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197702000-00008

    authors: Gelernt IM,Bauer JJ,Kreel I

    更新日期:1977-02-01 00:00:00

  • The Unconventional Role for Gastric Volume in the Response to Bariatric Surgery for Both Weight Loss and Glucose Lowering.

    abstract:OBJECTIVE:To study the relationship between the amount of surgery-induced gastric volume reduction and long-term weight loss and glucose tolerance. BACKGROUND DATA:Vertical sleeve gastrectomy (VSG) has recently surpassed gastric bypass to become the most popular surgical intervention to induce sustained weight loss. B...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003240

    authors: Evers SS,Lewis AG,Tong C,Shao Y,Alvarez R,Ridelman E,Grant B,Seeley RJ

    更新日期:2020-06-01 00:00:00

  • Experimental gastric sympathectomy: an effective prophylaxis of gastric stress lesions.

    abstract::Fifteen mini-pigs were bled to a mean aortic blood pressure of 40 mm Hg and maintained at that level for three hours. The control group consisted of eight animals with shock for three hours, while the test group was comprised of seven animals with a similar shock period but which had undergone splanchnicectomy 14 days...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197712000-00019

    authors: Hottenrott C,Seufert RM,Kühne FW,Büsing M

    更新日期:1977-12-01 00:00:00

  • Adjuvant radiotherapy is associated with increased sexual dysfunction in male patients undergoing resection for rectal cancer: a predictive model.

    abstract:OBJECTIVES:The objectives of this study were to evaluate the effect of radiotherapy (RT) on sexual function in patients undergoing oncologic resection for rectal cancer, and to develop a mathematical model for quantifying the risk of sexual dysfunction through time for this group of patients. METHODS:Data were prospec...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000183608.24549.68

    authors: Heriot AG,Tekkis PP,Fazio VW,Neary P,Lavery IC

    更新日期:2005-10-01 00:00:00

  • Lethal "thin" malignant melanoma. Identifying patients at risk.

    abstract::Thin melanomas can metastasize and be lethal. The purpose of this review was to identify negative risk factors in patients with melanomas less than 0.76 mm thick. Six hundred and eighty-one (681) such patients are reviewed in this study. Of those referred without metastatic disease (583 patients), metastases developed...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198808000-00004

    authors: Slingluff CL Jr,Vollmer RT,Reintgen DS,Seigler HF

    更新日期:1988-08-01 00:00:00

  • What have we learned about primary liver transplantation under tacrolimus immunosuppression? Long-term follow-up of the first 1000 patients.

    abstract:OBJECTIVE:To summarize the long-term efficacy and safety of tacrolimus in orthotopic liver transplant (OLT) recipients, as well as to examine the factors that influence long-term morbidity and mortality rates. BACKGROUND:Tacrolimus (FK506, Prograf) was introduced as primary immunosuppression for primary liver transpla...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199909000-00016

    authors: Jain A,Reyes J,Kashyap R,Rohal S,Abu-Elmagd K,Starzl T,Fung J

    更新日期:1999-09-01 00:00:00

  • Incorporation of Procedure-specific Risk Into the ACS-NSQIP Surgical Risk Calculator Improves the Prediction of Morbidity and Mortality After Pancreatoduodenectomy.

    abstract:OBJECTIVE:This multicenter study sought to evaluate the accuracy of the American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) surgical risk calculator for predicting outcomes after pancreatoduodenectomy (PD) and to determine whether incorporating other factors improves its predictive ...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000001796

    authors: McMillan MT,Allegrini V,Asbun HJ,Ball CG,Bassi C,Beane JD,Behrman SW,Berger AC,Bloomston M,Callery MP,Christein JD,Dickson E,Dixon E,Drebin JA,Fernandez-Del Castillo C,Fisher WE,Fong ZV,Haverick E,Hollis RH,House MG

    更新日期:2017-05-01 00:00:00

  • Association of adult celiac disease with surgical abdominal pain: a case-control study in patients referred to secondary care.

    abstract:BACKGROUND:Acute abdominal pain is the most common indication for surgical admission. Nonspecific abdominal pain (NSAP) may account for up to 40% of cases. There has been no published prospective study in which adult patients presenting with acute abdominal pain are investigated for celiac disease. AIMS:We aimed to as...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000171301.35513.cf

    authors: Sanders DS,Hopper AD,Azmy IA,Rahman N,Hurlstone DP,Leeds JS,George RR,Bhala N

    更新日期:2005-08-01 00:00:00

  • Nonfunctioning islet cell tumors.

    abstract::In nonfunctioning islet cell tumors of the pancreas, hormone production is not clinically evident. This type of tumor constituted 15% of all islet cell tumors seen at the Mayo Clinic from 1960 through 1978. Although identical to functioning islet cell tumors embryologically and histologically, the nonfunctioning tumor...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198102000-00010

    authors: Kent RB 3rd,van Heerden JA,Weiland LH

    更新日期:1981-02-01 00:00:00