Neurochemical and cellular markers in human cervix of late pregnant, postpartal and non-pregnant women.

Abstract:

BACKGROUND:The aim was to evaluate the peptidergic innervation and the dendritic cell content in the cervix uteri. METHODS:Cervical biopsies were obtained from late pregnant (n=5), postpartal (n=5) and non-pregnant (n=5) women. The samples were prepared for immunohistochemistry using antibodies to protein S-100 (S-100), calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP), human peptide histidine isoleucine amide (PHM 27), neuropeptide tyrosine (NPY), and human histocompatibility complex class II subregion DR (HLA-DR). RESULTS:Nerve fibers positive for protein S-100, and dendritic cells positive for S-100 and HLA-DR were abundant in the cervix, especially at late pregnancy. CGRP, VIP, PHM-27 and NPY positive nerve fibers were present in non-pregnant, short nerve fibers and scattered immunoreactivity at term, and further scattered immunoreactivity after parturition. NPY positive nerve fibers were decreased at term, and after parturition a scattered immunoreactivity was observed. CONCLUSIONS:The abundant protein S-100 positive nerve fibers implies an impact of myelinated nerves in the cervix uteri during pregnancy. The abundant dendritic cells, positive for HLA-DR and S-100, especially at term, indicates a general activation of the immune system until late pregnancy and parturition. The changed occurrence and distribution of immunoreactivity for CGRP, VIP and PHM-27 suggest a release of these neuropeptides until term. The changes in NPY immunoreactivity indicate a release of NPY around parturition.

authors

Stjernholm Y,Sennström M,Granström L,Ekman G,Liang Y,Johansson O

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

528-37

issue

7

eissn

0001-6349

issn

1600-0412

journal_volume

79

pub_type

杂志文章
  • Tubal artery blood flow in evaluation of tubal pregnancy.

    abstract:OBJECTIVE:To evaluate whether the assessment of tubal blood flow can indicate the side of the total pregnancy. METHODS:Using transvaginal color Doppler ultrasonography, we measured blood flow in the total arteries on both sides in 46 women with early ectopic pregnancy. We compared the resistance index (RI) and pulsati...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016349609065739

    authors: Stefanovic V,Cacciatore B,Ylöstalo P

    更新日期:1996-09-01 00:00:00

  • Prepregnancy body mass index influences lipid oxidation rate during pregnancy.

    abstract:INTRODUCTION:The influence of maternal body mass index (BMI) on respiratory quotient during pregnancy is not clear. We aim to evaluate longitudinal changes in energy expenditure, respiratory quotient, and substrate oxidation rates in normal and overweight women with uncomplicated pregnancies. We hypothesized that the t...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13058

    authors: Bugatto F,Quintero-Prado R,Vilar-Sánchez JM,Perdomo G,Torrejón R,Bartha JL

    更新日期:2017-02-01 00:00:00

  • Prospective study of incidence and predisposing factors for clavicular fracture in the newborn.

    abstract:OBJECTIVE:To determine the incidence of clavicular fracture, associated fetal and maternal risk factors and its connection with quality care control. SUBJECTS AND METHODS:A total of 3030 newborns delivered vaginally were evaluated for clavicular fractures by three separate physicians. The study group included all newb...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349609033335

    authors: Many A,Brenner SH,Yaron Y,Lusky A,Peyser MR,Lessing JB

    更新日期:1996-04-01 00:00:00

  • Shear-wave sonoelastographic assessment of cervix in pregnancy.

    abstract:INTRODUCTION:The aim of this study was to investigate the differences in shear-wave sonoelastography (SWS) scores between the different parts of cervix, explore the association between the cervical SWS scores with cervical length and evaluate repeatability of the measurement of cervical SWS scores. MATERIAL AND METHOD...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/aogs.13874

    authors: Duan H,Chaemsaithong P,Ju X,Ho SYS,Sun Q,Tai YY,Leung TY,Poon LC

    更新日期:2020-11-01 00:00:00

  • Is a speculum examination sufficient for excluding the diagnosis of ruptured fetal membranes?

    abstract:OBJECTIVE:To determine the false negative rate of a sterile speculum examination for the diagnosis of rupture of the membranes in women not in labor and without visible amniotic fluid at speculum examination. Furthermore, possible risks to the mother and the baby after suspected rupture of the membranes were analyzed. ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349709024339

    authors: Ladfors L,Mattsson LA,Eriksson M,Fall O

    更新日期:1997-09-01 00:00:00

  • Total intra-uterine volume and symphysis fundus height. Is there a relation?

    abstract::The concordance between measurements of total intra-uterine volume (parallel planimetric area method) and symphysis fundus height and the efficacy of these measurements in predicting birthweight by centile range was prospectively investigated in a blind study of 81 measurement sets in 74 women in the third trimester o...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348709103650

    authors: Geirsson RT,Agustsson P

    更新日期:1987-01-01 00:00:00

  • Treatment with hachimijiogan, a non-ergot Chinese herbal medicine, in two hyperprolactinemic infertile women.

    abstract::Two hyperprolactinemic infertile women, one with and one without a pituitary adenoma, who were resistant to bromocriptine treatment, were treated orally with Hachimijiogan, a Chinese herbal medicine. This treatment reduced the serum prolactin level, resulting in a normal ovulatory cycle and pregnancy, without side eff...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348909021028

    authors: Usuki S,Kubota S,Usuki Y

    更新日期:1989-01-01 00:00:00

  • Prescribing during pregnancy and lactation with reference to the Swedish classification system. A population-based study among Danish women.

    abstract:AIM:To assess the current prescribing pattern for 15,756 primiparae before, during, and after their pregnancies with reference to fetal and neonatal risk. METHOD:A prescription database study with linkage to The Danish Medical Birth Registry from 1991 to 1996. The drug subsidy system in Danish retail pharmacies, made ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.1999.780805.x

    authors: Olesen C,Sørensen HT,de Jong-van den Berg L,Olsen J,Steffensen FH,The Euromap Group

    更新日期:1999-09-01 00:00:00

  • Birth defects and paternal occupational exposure. Hypotheses tested in a record linkage based dataset.

    abstract:UNLABELLED:MAIN QUESTION: To test previously established hypotheses on associations of birth defects with paternal occupation on the basis of a Norwegian registry material. METHODS:The study comprised all births in Norway 1970 -1993 for which linkage with population censuses 1970, -80 and -90 on parents' job title cou...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Irgens A,Krüger K,Skorve AH,Irgens LM

    更新日期:2000-06-01 00:00:00

  • Hemangioma of the umbilical cord.

    abstract::A case of intrauterine fetal death with a hemangioma and pseudocysts in the umbilical cord is presented. The clinical significance of these rare lesions is not entirely clarified, but of the 20 fully documented cases of umbilical cord hemangiomas, including the present case, only nine were found with live and complete...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.3109/00016349409006260

    authors: Søndergaard G

    更新日期:1994-05-01 00:00:00

  • Bipolar cautery for laparoscopic sterilization.

    abstract::Laparoscopic sterilization with a bipolar electrode was performed in 62 patients. The sterilization failed in one patient and was questionable in another. The effectiveness was assessed by hysterosalpingography (HSG) in 51 patients. No complications due to laparoscopy occurred. The method is considered to be advantage...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347809155898

    authors: Gregersen E,Kjer JJ

    更新日期:1978-01-01 00:00:00

  • Normative values of Doppler velocimetry of five major fetal arteries as determined by color power angiography.

    abstract:OBJECTIVE:To produce normograms of Doppler indices of major fetal arteries and their ratios relative to the ascending aorta in a cohort of appropriately grown for gestational age fetuses. METHODS:Prospective longitudinal study of 70 women with appropriately grown for gestational age fetuses between 24 and 38 weeks' ge...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2005.00549.x

    authors: Konje JC,Abrams KR,Taylor DJ

    更新日期:2005-03-01 00:00:00

  • Bacteriological study of amniotic fluid during labor.

    abstract::Amniotic fluid from 207 women in labor was analysed at the time of artificial rupture of membranes or by amniocentesis. The following organisms were identified in concentrations of more than 1 000/ml: Staphylococcus aureus (1), Propionibacterium (1), E. coli (1), group B Streptococci (3), Lactobacilli (16). The 6 pati...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348309156257

    authors: Maye DP,Filthuth I,Pugin P,Waldvogel F,Herrman WL

    更新日期:1983-01-01 00:00:00

  • Impact of medico-legal findings on charge filing in cases of rape in adult women.

    abstract:OBJECTIVE:To assess the impact of the medical documentation and biological trace evidence in rape cases on the legal process. DESIGN:Retrospective descriptive study. SETTING AND SAMPLE:Police-reported cases of rape of women ≥16 years old in the Norwegian county of Sør-Trøndelag from January 1997 to June 2003. METHOD...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2011.01246.x

    authors: Hagemann CT,Stene LE,Myhre AK,Ormstad K,Schei B

    更新日期:2011-11-01 00:00:00

  • Oxytocin, somatostatin, insulin and gastrin concentrations vis-à-vis late pregnancy, breastfeeding and oral contraceptives.

    abstract::Oxytocin concentrations increased during pregnancy and during medication with low-dose oral contraceptives (o.c.). Postprandial somatostatin concentrations were lower during medication with o.c. Insulin concentrations were elevated during pregnancy with the same tendency during medication with o.c. Gastrin levels were...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349109007873

    authors: Silber M,Larsson B,Uvnäs-Moberg K

    更新日期:1991-01-01 00:00:00

  • Prolactin responsiveness to TRH in amenorrheic women with and without galactorrhea.

    abstract::Sixty women were given intravenous injection of 200 microgram TRH to assess its diagnostic potential as a stimulus to PRL release. Following the administration of TRH, there was a prompt increase in serum PRL to 614.6%, to 296%, to 282.1%, and 34% in normal women, amenorrheic patients, non tumoral galactorrheic cases,...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347709154988

    authors: MacGregor C,Maldonado D,Canales ES,Soria J,Zárate A

    更新日期:1977-01-01 00:00:00

  • Who uses Norplant. A study from Finland.

    abstract:OBJECTIVE:Although Norplant implantable contraceptives were introduced first in Finland, their use has been infrequent. The objective of this study was to investigate what kind of women use Norplant in Finland, who suggested its use, and from what source women get their information on Norplant. METHODS:A questionnaire...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409013435

    authors: Sihvo S,Ollila E,Hemminki E

    更新日期:1994-07-01 00:00:00

  • First trimester diagnosis and early in utero treatment of obstructive uropathy.

    abstract::The earliest diagnosis and treatment of obstructed fetal bladder is reported. Placement of vesico-amniotic shunt at 14.5 weeks of gestation enabled preservation of bilateral renal function and maintenance of normal amniotic fluid volume with normal pulmonary development. The shunt functioned adequately for more than 1...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348909013286

    authors: Drugan A,Zador IE,Bhatia RK,Sacks AJ,Evans MI

    更新日期:1989-01-01 00:00:00

  • Maternal demographics and hemodynamics for the prediction of fetal growth restriction at booking, in pregnancies at high risk for placental insufficiency.

    abstract:INTRODUCTION:Fetal growth restriction (FGR) is associated with poor perinatal outcomes. Screening and prevention tools for FGR, such as uterine artery Doppler imaging and aspirin, underperform in high-risk groups, compared with general antenatal populations. There is a paucity of sensitive screening tests for the early...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12823

    authors: Stott D,Bolten M,Salman M,Paraschiv D,Clark K,Kametas NA

    更新日期:2016-03-01 00:00:00

  • Fetal cardiovascular hemodynamics in type 1 diabetic pregnancies at near-term gestation.

    abstract:INTRODUCTION:Poor glycemic control in maternal type 1 diabetes mellitus during pregnancy can affect fetal cardiac and placental function. However, studies concerning fetal central hemodynamics have revealed conflicting results. We hypothesized that in pregnancies complicated by maternal type 1 diabetes, fetal cardiovas...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13987

    authors: Lehtoranta L,Haapsamo M,Vuolteenaho O,Palo P,Ekholm E,Räsänen J

    更新日期:2021-02-01 00:00:00

  • The association of maternal country of birth and education with hypertensive disorders of pregnancy: A population-based study of 960 516 deliveries in Norway.

    abstract:INTRODUCTION:Previous studies estimating the association of maternal country of birth and education with hypertensive disorders of pregnancy (HDP) have shown conflicting results. The aim of the study was to assess the prevalence of HDP and estimate the association of maternal country of birth and education level with p...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13393

    authors: Sole KB,Staff AC,Laine K

    更新日期:2018-10-01 00:00:00

  • Pregnancy outcome after metroplasty in women with müllerian anomalies.

    abstract::Pregnancy outcomes in 22 consecutively operated women with Müllerian anomalies are described. In 16 women the indication for metroplasty was two or more spontaneous abortions and/or premature deliveries. The frequency of successful pregnancies increased from 5% before to 76% after operation. In 6 women metroplasty was...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348809004205

    authors: Helm P,Stampe Sørensen S

    更新日期:1988-01-01 00:00:00

  • Direct current conversion of maternal supraventricular tachycardia developed during the treatment of a pregnant heroin addict with ritodrine.

    abstract::During ritodrine (UtoparR) treatment for premature labor, a chronic heroin-addicted patient developed supraventricular tachycardia which was treated by direct current (d.c) conversion, d.c. conversion did not affect the fetus, as judged by the cardiotocogram. As heroin addicts run an increased risk or developing cardi...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348109155476

    authors: Fink BJ,Weber T

    更新日期:1981-01-01 00:00:00

  • Treatment of ectopic pregnancy by local injection of hypertonic glucose: a randomized trial comparing administration guided by transvaginal ultrasound or laparoscopy.

    abstract:OBJECTIVE:To study local treatment of ectopic pregnancy by injection of hyperosmolar (50%) glucose, guided either by transvaginal ultrasound or by laparoscopy. METHODS:Eighty women were randomized, 39 into the sonography and 41 into the laparoscopy group. Criteria for inclusion were 1) ectopic pregnancy < or = 4 cm se...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016349509013476

    authors: Gjelland K,Hordnes K,Tjugum J,Augensen K,Bergsjø P

    更新日期:1995-09-01 00:00:00

  • Background factors and scoring systems in relation to pregnancy outcome after fertility surgery.

    abstract:BACKGROUND:A study was initiated to identify background factors, clinical features and pre-operative scoring systems of importance for future selection of patients suitable for fertility surgery. METHODS:Surgical procedures, background factors and scoring systems for tubal lesions and adnexal adhesions and risk factor...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349509024450

    authors: Strandell A,Bryman I,Janson PO,Thorburn J

    更新日期:1995-04-01 00:00:00

  • A national, prospective observational study of first recurrence after primary treatment for gynecological cancer in Norway.

    abstract:INTRODUCTION:Gynecological cancer patients are routinely followed up for five years after primary treatment. However, the value of such follow up has been debated, as retrospective studies indicate that first recurrence is often symptomatic and occurs within two to three years of primary treatment. We prospectively inv...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13199

    authors: Vistad I,Bjørge L,Solheim O,Fiane B,Sachse K,Tjugum J,Skrøppa S,Bentzen AG,Stokstad T,Iversen GA,Salvesen HB,Kristensen GB,Dørum A

    更新日期:2017-10-01 00:00:00

  • Reactive sacroiliitis as late sequela after severe pelvic inflammatory disease verified by laparoscopy or laparotomy.

    abstract:OBJECTIVE:To investigate the frequency of lumbosacral pains and sacroiliitis as late sequela of severe pelvic inflammatory disease (PID) confirmed by laparoscopy or laparotomy. DESIGN:The sacroiliac joints were examined radiographically and scintigraphically to search for signs of reactive sacroiliitis. SETTING:Depar...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409015772

    authors: Mozas J,Castilla JA,Alarcón JL,López JM,García JL,Herruzo AJ

    更新日期:1994-04-01 00:00:00

  • Feasibility study of using fetal DNA in maternal plasma for non-invasive prenatal diagnosis.

    abstract:BACKGROUND:The discovery of the presence of fetal genetic material in maternal blood has opened up a new approach to prenatal diagnosis. One approach that has been extensively investigated over the past few decades is the isolation of fetal cells from maternal blood (Herzenberg et al. Proc Natl Acad Sci USA. 1979;76:14...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016340601159124

    authors: Liu FM,Wang XY,Feng X,Wang W,Ye YX,Chen H

    更新日期:2007-01-01 00:00:00

  • Preoperative and intraoperative assessment of myometrial invasion in endometrial cancer: comparison of magnetic resonance imaging and frozen sections.

    abstract:OBJECTIVE:To compare the diagnostic characteristics of the evaluation of myometrial invasion (MI) retrospectively between preoperative magnetic resonance imaging (MRI) and intraoperative frozen sections. DESIGN:A retrospective study. SETTING:University hospital. SAMPLE:201 women diagnosed with endometrial carcinoma....

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12048

    authors: Kisu I,Banno K,Lin LY,Ueno A,Abe T,Kouyama K,Okuda S,Masugi Y,Umene K,Nogami Y,Tsuji K,Masuda K,Ueki A,Kobayashi Y,Yamagami W,Susumu N,Aoki D

    更新日期:2013-05-01 00:00:00

  • Regional and temporal variation in hysterectomy rates and surgical routes for benign diseases in the Netherlands.

    abstract:OBJECTIVE:To provide descriptive statistics on hysterectomy for benign gynecological conditions in the Netherlands and to analyze regional and temporal variations in hysterectomy rates and surgical routes. DESIGN:Retrospective cohort study. SETTING:Dutch hospitals. POPULATION:All women with a hysterectomy for benign...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2011.01309.x

    authors: Hanstede MM,Burger MJ,Timmermans A,Burger MP

    更新日期:2012-02-01 00:00:00