Osteogenic induction in hereditary disorders of heterotopic ossification.

abstract：:The absolute treatment of extensively involved cases of Legg-Calvé-Perthes disease (LCPD) remains unsolved. The basic principle of adequate containment of the capital femoral epiphysis in its acetabulum while minimizing the disability time is widely accepted, but the definition of adequate containment and methods of a...

journal_title：Clinical orthopaedics and related research

authors： Cotler JM,Donahue J

更新日期：1980-07-01 00:00:00

abstract：:Recombinant human bone morphogenetic protein-2 is an osteoinductive protein that plays a pivotal role in bone growth and regeneration. Several hundred studies were conducted in the past 7 years in numerous animal models to establish unequivocally the efficacy, safety, mechanism of action, pharmacokinetics, and surgica...

journal_title：Clinical orthopaedics and related research

authors： Valentin-Opran A,Wozney J,Csimma C,Lilly L,Riedel GE

更新日期：2002-02-01 00:00:00

abstract：:Hip osteoarthritis is a common cause of musculoskeletal pain in older adults and may result in decreased mobility and quality of life. Although the presentation of hip osteoarthritis varies, surgical management is required when the disease is severe, longstanding, and unresponsive to nonoperative treatments. For stake...

journal_title：Clinical orthopaedics and related research

authors： Dagenais S,Garbedian S,Wai EK

更新日期：2009-03-01 00:00:00

abstract：:Supplements of glucosamine hydrochloride, low molecular weight chondroitin sulfate, and manganese ascorbate were tested separately and in combination for their ability to retard progression of cartilage degeneration in a rabbit instability model of osteoarthrosis. Computerized quantitative histologic evaluation of saf...

journal_title：Clinical orthopaedics and related research

authors： Lippiello L,Woodward J,Karpman R,Hammad TA

更新日期：2000-12-01 00:00:00

abstract：:Resistant hip infection in adults can be a complicated problem that does not respond to surgical and medical treatment. In such cases, the only remaining option is excision arthroplasty. This line of treatment can eradicate the infection but also is associated with poor function. In some cases, conversion of excision ...

journal_title：Clinical orthopaedics and related research

authors： Emara KM

更新日期：2008-03-01 00:00:00

abstract：:When perichondrium-free pieces of embryonic quail epiphyseal cartilage are incubated on the chorioallantoic membranes of chick embryos, 2 developmental changes are observed. First, most grafts develop a periosteum in which the osteoblasts and osteocytes are of donor, i.e., chondrocytic origin. No such periosteum is ob...

journal_title：Clinical orthopaedics and related research

authors： Kahn AJ,Simmons DJ

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Patient-specific CT-based instrumentation may reduce implant malpositioning and improve alignment in TKA. However, it is not known whether this innovation is an advance that benefits patients. QUESTIONS/PURPOSES:We evaluated (1) the precision of patient-specific TKA by comparing the incidence of outliers in...

journal_title：Clinical orthopaedics and related research

authors： Roh YW,Kim TW,Lee S,Seong SC,Lee MC

更新日期：2013-12-01 00:00:00

abstract：:Fetal tendons and skin heal regeneratively without scar formation. Cells isolated from these fetal tissues exhibit enhanced cellular migration and collagen production in comparison to cells from adult tissue. We determined whether fetal and adult fibroblasts isolated from the anterior cruciate ligament (ACL), a tissue...

journal_title：Clinical orthopaedics and related research

authors： Stalling SS,Nicoll SB

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:During hip arthroplasties for treating proximal femur metastases, a long femoral stem frequently is used, presumably protecting the entire femur against progression of the existing lesions or development of new lesions. However, it is unclear whether a long stem is really required. QUESTIONS/PURPOSES:We the...

journal_title：Clinical orthopaedics and related research

authors： Xing Z,Moon BS,Satcher RL,Lin PP,Lewis VO

更新日期：2013-05-01 00:00:00

abstract：UNLABELLED:The anterolateral approach in the supine position provides excellent visualization of the acetabulum. The main advantage of the approach, a low dislocation rate, has been demonstrated in the literature, while the purported disadvantage of abductor dysfunction has not been clearly delineated in the literature...

journal_title：Clinical orthopaedics and related research

authors： Austin MS,Rothman RH

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:An assortment of variables has been used in predicting anterior shoulder instability resulting from pathologic engagement of Hill-Sachs lesions on the glenoid. The glenoid track is a unique biomechanical model that relates both Hill-Sachs and bony Bankart lesions to predict shoulder engagement. We examined t...

journal_title：Clinical orthopaedics and related research

authors： Trivedi S,Pomerantz ML,Gross D,Golijanan P,Provencher MT

更新日期：2014-08-01 00:00:00

abstract：:Both cost effectiveness and safety can be realized in the operation of a community bone bank by adoption of the following measures: deep freezing, rather than freeze drying; allogenic bone is collected from femoral heads excised from total hip arthroplasties; and careful donor and graft selection controls ensure an al...

journal_title：Clinical orthopaedics and related research

authors： Hart MM,Campbell ED Jr,Kartub MG

更新日期：1986-05-01 00:00:00

abstract：:Stress deprivation alters the morphologic, biochemical, and biomechanical characteristics of various components of synovial joints. Prominent among the protean changes that result are proliferation of fibrofatty connective tissue within the joint space, adhesions between synovial folds, adherence of fibrofatty connect...

journal_title：Clinical orthopaedics and related research

authors： Akeson WH,Amiel D,Abel MF,Garfin SR,Woo SL

更新日期：1987-06-01 00:00:00

abstract：:A simple, effective technique for internal fixation of the clavicle with Knowles threaded pins is described in 11 patients with 1 to 21 year results. The method is applicable to fresh fractures of non-union and provides secure compression-fixation. The threads prevent migration of the pin, reduce the period of externa...

journal_title：Clinical orthopaedics and related research

authors： Neviaser RJ,Neviaser JS,Neviaser TJ,Neviaser JS

更新日期：1975-01-01 00:00:00

abstract：:A 14-year-old girl with painful scoliosis was found to have an osteoid osteoma involving the body of the left seventh rib. Excision of the tumor was facilitated by intraoperative bone scanning that precisely located its position. Following surgery, preoperative pain was completely relieved and the spinal curvature had...

journal_title：Clinical orthopaedics and related research

authors： Mehdian H,Summers B,Eisenstein S

更新日期：1988-05-01 00:00:00

abstract：:It is now well established that the meniscus performs a number of roles that are important to the efficient performance of the knee joint. Of particular importance is the recognition of its load-bearing function and its stabilization of the joint during flexion-extension. The compression of the wedge-shaped meniscus d...

journal_title：Clinical orthopaedics and related research

authors： Ghosh P,Taylor TK

更新日期：1987-11-01 00:00:00

abstract：:The interpretation of loosening on the basis of contrast flow about the cement-bone interface in arthrograms of total knee arthroplasties includes special considerations. The first is that arthrography is misleading in the presence of severe cystic changes. The second is that clinical criteria should be given priority...

journal_title：Clinical orthopaedics and related research

authors： Major M,Johnson RP,Carrera G,Hussey C

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Biocomposite suture anchors containing osteoconductive materials have gained popularity in rotator cuff repairs. However, little is known about the influence of the addition of osteoconductive materials on implant resorption, bone reaction, tendon healing, and clinical outcomes scores. QUESTIONS/PURPOSES:(1...

journal_title：Clinical orthopaedics and related research

authors： Sgroi M,Friesz T,Schocke M,Reichel H,Kappe T

更新日期：2019-06-01 00:00:00

abstract：:Intracapsular fractures of the hip have been classified by different authors with a basis on various concepts. Pauwels classified these fractures according to the angle of inclination; Linton used trabecular disposition among the fractural fragments, and Garden described four types according to the order of displaceme...

journal_title：Clinical orthopaedics and related research

authors： Caviglia HA,Osorio PQ,Comando D

更新日期：2002-06-01 00:00:00

abstract：:Nonunion is a frequent complication of displaced intracapsular fractures of the femoral neck and occurs in as many as 43% of patients. The incidence can be reduced by prompt anatomic reduction and stable fixation. The treatment of an established nonunion depends on numerous factors including the age of the patient, th...

journal_title：Clinical orthopaedics and related research

authors： Jackson M,Learmonth ID

更新日期：2002-06-01 00:00:00

abstract：:In a series of children's hip fracture seen over a 27-year-period, there were 39 patients (40 fractures) with a mean age of 8.9 years followed for an average 7 years. After an initial period of traction, 50% of the fractures were treated in a spica cast, 40% by internal fixation, and 10% by bed rest. Overall, there we...

journal_title：Clinical orthopaedics and related research

authors： Heiser JM,Oppenheim WL

更新日期：1980-06-01 00:00:00

abstract：:Fifteen patients with fracture of the axis arch ("Hangman's Fracture" of the cervical spine) reviewed with regard to the clinical features, mechanism of injury and management, present a relatively high rate of cord involvement (11 patients) and injuries around the jaw (5 patients). All of the injuries occurred in civi...

journal_title：Clinical orthopaedics and related research

authors： Marar BC

更新日期：1975-01-01 00:00:00

abstract：:In this prospective, randomized, controlled study, we compared the performance of conventional and navigated total knee arthroplasties. Component alignment was measured in 60 patients operated on using navigation and in 60 patients operated on using the conventional technique. The groups then were divided into a subpo...

journal_title：Clinical orthopaedics and related research

authors： Ensini A,Catani F,Leardini A,Romagnoli M,Giannini S

更新日期：2007-04-01 00:00:00

abstract：:The purpose of the current study was to evaluate the long-term results of the Kinematic I condylar prosthesis with retention of the posterior cruciate ligament. One hundred sixty-eight total knee arthroplasties in 118 patients (mean age, 65.2 years; range, 21-88 years) were inserted with cement, an all-polyethylene pa...

journal_title：Clinical orthopaedics and related research

authors： Sextro GS,Berry DJ,Rand JA

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Periprosthetic joint infection (PJI) following total joint arthroplasty is a serious complication that causes severe morbidity and adds a major financial burden to the healthcare system. Although there is plenty of research on the alpha-defensin (AD) test, a meta-analysis consisting of only prospective studi...

journal_title：Clinical orthopaedics and related research

authors： Kuiper JWP,Verberne SJ,Vos SJ,van Egmond PW

更新日期：2020-06-01 00:00:00

abstract：:Osteosarcoma is the most common primary bone malignancy. Despite improvements in therapy, approximately 30% of patients experience pulmonary metastasis. Expression of several growth factors, including VEGF and BMPs, has been implicated in tumor progression and metastatic potential. We hypothesized increased metastatic...

journal_title：Clinical orthopaedics and related research

authors： Weiss KR,Cooper GM,Jadlowiec JA,McGough RL 3rd,Huard J

更新日期：2006-09-01 00:00:00

abstract：:The literature on the biomechanics of the intervertebral disk is reviewed with emphasis on biomechanical--biochemical--morphological correlative studies. The deficiency of definitive correlative studies is apparent and an appeal is made to interested investigators to fill in the voids in this extremely important area ...

journal_title：Clinical orthopaedics and related research

authors： Akeson WH,Woo SL,Taylor TK,Ghosh P,Bushell GR

更新日期：1977-11-01 00:00:00

abstract：:Cartilage function after resurfacing with cell-based transplantation procedures or during the early stages of arthritic disease may be bolstered by the addition of growth factor genes to the transplanted tissue. Insulinlike growth factor-I maintains chondrocyte metabolism in normal cartilage homeostasis and has been s...

journal_title：Clinical orthopaedics and related research

authors： Nixon AJ,Brower-Toland BD,Bent SJ,Saxer RA,Wilke MJ,Robbins PD,Evans CH

更新日期：2000-10-01 00:00:00

abstract：:During a 5 year period 50 patients with chronic low back pain, with or without sciatica due to a proven lumbosacral disk lesion, underwent a spinal fusion using the Boucher method of screw fixation of the facet joints. The L-4 spinous process was excised and fashioned into an H-shape to act as the bone graft between t...

journal_title：Clinical orthopaedics and related research

authors： Graham CE

更新日期：1979-05-01 00:00:00

abstract：:In a 37-year-old man, bilateral infraspinatus muscle weakness was associated with compression of the suprascapular nerve. The compression occurred at the spinoscapular angle by bilateral development of ganglia. The lesion was confirmed by electromyography. Surgical approaches to the area are described along with a rev...

journal_title：Clinical orthopaedics and related research

authors： Thompson RC Jr,Schneider W,Kennedy T

更新日期：1982-06-01 00:00:00