Pneumomediastinum in dermatomyositis: association with cutaneous vasculopathy.

abstract：:A case is reported of polytenosynovitis in a 31-year-old male during the course of a severe bacteraemic illness caused by Haemophilus influenzae type b. The clinical presentation was similar to tenosynovitis caused by bacterial or viral agents. As the management of the H. influenzae tenosynovitis would differ from tha...

journal_title：Annals of the rheumatic diseases

authors： Bansal S,Magnussen CR,Napodano RJ

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To carry out a critical appraisal of the literature in an attempt to assess the current value of synovial fluid (SF) analysis in the diagnosis of joint disease. METHODS:A literature search was undertaken using the Medline, Biomed, Bids, Pubmed, and Embase electronic databases using the keywords: synovial flu...

journal_title：Annals of the rheumatic diseases

authors： Swan A,Amer H,Dieppe P

更新日期：2002-06-01 00:00:00

abstract：:In this retrospective study of 57 patients with primary hyperparathyroidism who underwent parathyroidectomy, the overall incidence of chondrocalcinosis was 40%. Neither joint symptoms nor chondrocalcinosis regressed after the operation. In several patients the condition appeared to deteriorate both clinically and radi...

journal_title：Annals of the rheumatic diseases

authors： Glass JS,Grahame R

更新日期：1976-12-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of age on the effectiveness and tolerance of antitumour necrosis factor alpha (TNFalpha) therapy in rheumatoid arthritis (RA). METHODS:730 patients of the Dutch Rheumatoid Arthritis Monitoring (DREAM) register were categorised into three groups according to their age at initiatio...

journal_title：Annals of the rheumatic diseases

authors： Radovits BJ,Kievit W,Fransen J,van de Laar MA,Jansen TL,van Riel PL,Laan RF

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Oxidative stress in RA synovial tissue can cause DNA damage and suppress the DNA mismatch repair (MMR) system in cultured synoviocytes. This mechanism includes two enzyme complexes, hMutSalpha (hMSH2/hMSH6) and hMutSbeta (hMSH2/hMSH3). OBJECTIVE:To examine the expression and distribution of MMR enzymes in s...

journal_title：Annals of the rheumatic diseases

authors： Simelyte E,Boyle DL,Firestein GS

更新日期：2004-12-01 00:00:00

abstract：:Three aspects of polymorphonuclear leucocyte (PMN) function were studied in 19 patients with Behçet's syndrome (BS). By 2 different techniques directed motility was found to be increased. This increase was largely due to the subgroup of patients with ocular involvement. Counts of absolute numbers of cells migrating hi...

journal_title：Annals of the rheumatic diseases

authors： Fordham JN,Davies PG,Kirk A,Currey HL

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVE:To analyse tender and swollen joint counts in three cohorts of patients with rheumatoid arthritis (RA), with a focus on the proportions of patients who had fewer than 6-12 tender or swollen joints, as possible evidence based information toward more generalisable inclusion criteria for current and future RA cl...

journal_title：Annals of the rheumatic diseases

authors： Pincus T,Sokka T,Chung CP,Cawkwell G

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:High rheumatoid arthritis (RA) disease activity during pregnancy is associated with a lower birth weight. Active RA is characterised by high circulating levels of cytokines, which can mediate placental growth and remodelling. OBJECTIVES:To assess the influence of maternal serum cytokine levels on birth weig...

journal_title：Annals of the rheumatic diseases

authors： de Steenwinkel FD,Hokken-Koelega AC,de Man YA,de Rijke YB,de Ridder MA,Hazes JM,Dolhain RJ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The effect of adalimumab on hand osteoporosis was examined and related to radiographic joint damage in the three treatment arms of the PREMIER study: adalimumab plus methotrexate, adalimumab and methotrexate monotherapy. Predictors of hand bone loss were also searched for. METHODS:768 patients (537 fulfilled...

journal_title：Annals of the rheumatic diseases

authors： Hoff M,Kvien TK,Kälvesten J,Elden A,Haugeberg G

更新日期：2009-07-01 00:00:00

abstract：:The first biological therapeutics in rheumatology are approaching patent expiration, encouraging development of 'follow-on' versions, known as 'biosimilars'. Biological agents range from simple replacement hormones to complex monoclonal antibodies and soluble receptors: large, intricate proteins with unique tertiary a...

journal_title：Annals of the rheumatic diseases

authors： Dörner T,Strand V,Castañeda-Hernández G,Ferraccioli G,Isaacs JD,Kvien TK,Martin-Mola E,Mittendorf T,Smolen JS,Burmester GR

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence and consultation rate of lower extremity complaints in general practice. METHODS:Data were obtained from the Second Dutch National Survey of General Practice, in which 195 general practitioners (GPs) in 104 practices recorded all contacts with patients during 12 consecutive months i...

journal_title：Annals of the rheumatic diseases

authors： van der Waal JM,Bot SD,Terwee CB,van der Windt DA,Schellevis FG,Bouter LM,Dekker J

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. METHODS:Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. F...

journal_title：Annals of the rheumatic diseases

authors： Franklin J,Ingvarsson T,Englund M,Lohmander LS

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:To study the short term effects of a single dose of D2E7, a fully human anti-tumour necrosis factor (TNFalpha) monoclonal antibody (mAb), on the local and systemic homeostasis of interleukin 1beta (IL1beta) and TNFalpha in patients with rheumatoid arthritis (RA). METHODS:All patients with RA enrolled in a p...

journal_title：Annals of the rheumatic diseases

authors： Barrera P,Joosten LA,den Broeder AA,van de Putte LB,van Riel PL,van den Berg WB

更新日期：2001-07-01 00:00:00

abstract：:Pain in the neck and upper limb is common and contributes considerably to absence from work due to sickness. Evidence suggest that prolonged abnormal posture and repetition contribute to such conditions. Psychosocial risk factors may also play a part in the aetiology of upper limb disorders. ...

journal_title：Annals of the rheumatic diseases

authors： Walker-Bone K,Cooper C

更新日期：2005-10-01 00:00:00

abstract：:We describe a patient with rheumatoid arthritis and widespread joint and periarticular calcinosis related to self-medication with vitamin D, which was aggravated by oral phosphate therapy prescribed for her hypercalcaemia. Hydroxyapatite was shown in the synovial fluid from affected joints. The role played by tissue i...

journal_title：Annals of the rheumatic diseases

authors： Butler RC,Dieppe PA,Keat AC

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:Reduced caveolin-1 levels in lung fibroblasts from patients with scleroderma and the lungs of bleomycin-treated mice promote collagen overexpression and lung fibrosis. This study was undertaken to determine whether caveolin-1 is deficient in leucocytes from bleomycin-treated mice and patients with scleroderm...

journal_title：Annals of the rheumatic diseases

authors： Tourkina E,Richard M,Oates J,Hofbauer A,Bonner M,Gööz P,Visconti R,Zhang J,Znoyko S,Hatfield CM,Silver RM,Hoffman S

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To investigate the production of the matrix metalloproteinase (MMP), collagenase (MMP-1), and its natural inhibitor, the tissue inhibitor of metalloproteinases (TIMP) by diseased human tendon samples in organ culture. METHODS:Portions of tendons were excised from the shoulders of patients undergoing shoulder...

journal_title：Annals of the rheumatic diseases

authors： Dalton S,Cawston TE,Riley GP,Bayley IJ,Hazleman BL

更新日期：1995-07-01 00:00:00

abstract：:The effect of transforming growth factor beta (TGF beta) on proteoglycan synthesis and degradation in anatomically intact articular cartilage of murine patellae was studied. Exogenously added TGF beta up to a concentration of 200 pmol/l had no effect on proteoglycan synthesis in intact articular cartilage. Neutralisat...

journal_title：Annals of the rheumatic diseases

authors： van der Kraan PM,Vitters EL,van den Berg WB

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:The RCA alpha block (Regulators of Complement Activation, 1q32) contains critical complement regulatory genes such as CR1 and MCP. This study examined RCA alpha block haplotype associations with both disease susceptibility and diversification of the anti-Ro/La autoantibody response in primary Sjögren syndrome...

journal_title：Annals of the rheumatic diseases

authors： Lester S,McLure C,Williamson J,Bardy P,Rischmueller M,Dawkins RL

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:There are no agreed criteria for osteoarthritis (OA) of the knee in population studies. The radiographic scoring system of Kellgren and Lawrence has been the system most used in the past and although other methods have been developed, comparisons have not been performed. Therefore these grading systems were ...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Hart DJ,Byrne J,Harris PA,Dacre JE,Doyle DV

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:There is emerging evidence that the development and progression of osteoarthritis (OA) is associated with inflammation. C reactive protein (CRP), a systemic marker for inflammation, may be elevated in OA patients but the evidence is conflicting. OBJECTIVE:To systematically review the literature for the rela...

journal_title：Annals of the rheumatic diseases

authors： Jin X,Beguerie JR,Zhang W,Blizzard L,Otahal P,Jones G,Ding C

更新日期：2015-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is highly prevalent in Malaysia, which has a mixed population of Malays, Chinese, and Indians. A quantitative enzyme linked immunosorbent assay (ELISA) was used to determine anticardiolipin antibody (aCL) levels (total immunoglobulin, IgG, and IgM) in 200 patients with SLE (164 Chine...

journal_title：Annals of the rheumatic diseases

authors： Jones HW,Ireland R,Senaldi G,Wang F,Khamashta M,Bellingham AJ,Veerapan K,Hughes GR,Vergani D

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVES:Although shared decision making (SDM) is advocated in rheumatoid arthritis (RA) treatment, it is largely unclear when, how and to what extent SDM is applied in routine clinical care of patients with RA. This study aimed to investigate the level of SDM in RA treatment from an observer perspective and to asses...

journal_title：Annals of the rheumatic diseases

authors： Mathijssen EGE,Vriezekolk JE,Popa CD,van den Bemt BJF

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:The aorta inhibits paravertebral ossification in diffuse idiopathic skeletal hyperostosis. We investigated if syndesmophytes in ankylosing spondylitis (AS) occurred less often at the vertebral rim near the aorta. METHODS:We performed thoracolumbar CT scans in 60 subjects in this cross-sectional study. The m...

journal_title：Annals of the rheumatic diseases

authors： Tan S,Dasgupta A,Flynn JA,Ward MM

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Systemic sclerosis (SSc) fibroblasts remain activated even in the absence of exogenous stimuli. Epigenetic alterations are thought to play a role for this endogenous activation. Trimethylation of histone H3 on lysine 27 (H3K27me3) is regulated by Jumonji domain-containing protein 3 (JMJD3) and ubiquitously t...

journal_title：Annals of the rheumatic diseases

authors： Bergmann C,Brandt A,Merlevede B,Hallenberger L,Dees C,Wohlfahrt T,Pötter S,Zhang Y,Chen CW,Mallano T,Liang R,Kagwiria R,Kreuter A,Pantelaki I,Bozec A,Abraham D,Rieker R,Ramming A,Distler O,Schett G,Distler JHW

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Interleukin (IL) 34 is a new cytokine implicated in macrophage differentiation and osteoclastogenesis. This study assessed IL-34 expression in the tissue of patients with rheumatoid arthritis (RA). METHODS:Immunohistochemistry was performed in synovial biopsies from patients with RA (n=20), osteoarthritis (...

journal_title：Annals of the rheumatic diseases

authors： Chemel M,Le Goff B,Brion R,Cozic C,Berreur M,Amiaud J,Bougras G,Touchais S,Blanchard F,Heymann MF,Berthelot JM,Verrecchia F,Heymann D

更新日期：2012-01-01 00:00:00

abstract：:Twenty seven patients with primary or possible Sjögren's syndrome with neurological manifestations were compared immunologically with 21 patients with Sjögren's syndrome with an intact nervous system. Patients with Sjögren's syndrome were divided into seropositive and seronegative subgroups with respect to the occurre...

journal_title：Annals of the rheumatic diseases

authors： Hietaharju A,Korpela M,Ilonen J,Frey H

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To carry out a prospective two year follow up study comparing conventional radiography, three-phase bone scintigraphy, ultrasonography (US), and three dimensional (3D) magnetic resonance imaging (MRI) with precontrast and dynamic postcontrast examination in detecting early arthritis. The aim of the follow up ...

journal_title：Annals of the rheumatic diseases

authors： Backhaus M,Burmester GR,Sandrock D,Loreck D,Hess D,Scholz A,Blind S,Hamm B,Bollow M

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To investigate the activation of NF-kappaB in the carrageenan rat air pouch model of inflammation in a time course experiment, and the effect of dexamethasone on NF-kappaB activation. METHODS:Air pouch tissue treated with carrageenan (inflamed tissue) was obtained from rats killed at days 1, 2, 3, 6, 14, 21,...

journal_title：Annals of the rheumatic diseases

authors： Ellis L,Gilston V,Soo CC,Morris CJ,Kidd BL,Winyard PG

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:To investigate the presence and functionality of oestrogen receptor alpha (ERalpha) in interleukin (IL)1beta-treated rabbit articular chondrocytes in culture, and to determine the mechanisms of 17beta oestradiol (E2) effects on IL1beta-induced inducible nitric oxide synthase (iNOS) expression. METHODS:The p...

journal_title：Annals of the rheumatic diseases

authors： Richette P,Dumontier MF,Tahiri K,Widerak M,Torre A,Benallaoua M,Rannou F,Corvol MT,Savouret JF

更新日期：2007-03-01 00:00:00