Abstract:
:The SERMs (selective estrogen receptor modulators) are a new class of molecules that bind to the estrogen receptor, resulting in an estradiol agonist or antagonist response according to the target tissue. Raloxifene, a new SERM, has been shown to prevent postmenopausal bone loss, to reduce the risk of vertebral fractures in osteoporotic women, to decrease serum cholesterol and its LDL fraction, and to reduce significantly the risk of breat cancer. Raloxifene is available in France for the prevention of post-menopausal osteoporosis.
journal_name
Joint Bone Spinejournal_title
Joint bone spineauthors
Delmas PDsubject
Has Abstractpub_date
2000-01-01 00:00:00pages
15s-22seissn
1297-319Xissn
1778-7254journal_volume
67 Suppl 1pub_type
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