[Clinical results of selective estrogen receptor modulators (SERM)].

Abstract:

:The SERMs (selective estrogen receptor modulators) are a new class of molecules that bind to the estrogen receptor, resulting in an estradiol agonist or antagonist response according to the target tissue. Raloxifene, a new SERM, has been shown to prevent postmenopausal bone loss, to reduce the risk of vertebral fractures in osteoporotic women, to decrease serum cholesterol and its LDL fraction, and to reduce significantly the risk of breat cancer. Raloxifene is available in France for the prevention of post-menopausal osteoporosis.

journal_name

Joint Bone Spine

journal_title

Joint bone spine

authors

Delmas PD

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

15s-22s

eissn

1297-319X

issn

1778-7254

journal_volume

67 Suppl 1

pub_type

杂志文章
  • Acromegaly is associated with vertebral deformations but not vertebral fractures: Results of a cross-sectional monocentric study.

    abstract:OBJECTIVES:Patients with acromegaly appear to be at increased risk of vertebral fractures despite normal bone mineral density. We investigated the prevalence of vertebral fractures in a cohort of acromegalic patients under 80 years of age. METHODS:Monocentric cross-sectional study performed at Nantes University Hospit...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2020.04.020

    authors: Plard C,Hochman C,Hadjadj S,Le Goff B,Maugars Y,Cariou B,Drui D,Guillot P

    更新日期:2020-12-01 00:00:00

  • Osteoporosis: Is milk a kindness or a curse?

    abstract::Cow's milk is often severely criticized as a cause of multiple health problems, including an increased risk of fractures. A close look at the scientific literature shows a striking contradiction. On the one hand, experimental studies of surrogate markers (e.g., bone turnover markers and bone mineral density [BMD]) usu...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2016.06.006

    authors: Fardellone P,Séjourné A,Blain H,Cortet B,Thomas T,GRIO Scientific Committee.

    更新日期:2017-05-01 00:00:00

  • Familial hypocalciuric hypercalcemia revealed by chondrocalcinosis.

    abstract:BACKGROUND:Calcium pyrophosphate dihydrate crystal deposition disease (CPPD-CDD) has been associated to hypercalcemia. Familial hypocalciuric hypercalcemia (FHH) is a rare but important consideration in the differential diagnosis of hypercalcemia. This autosomal dominantly inherited condition is characterized by elevat...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2009.02.001

    authors: Volpe A,Guerriero A,Marchetta A,Caramaschi P,Furlani L

    更新日期:2009-12-01 00:00:00

  • Kimura disease of extremity: unusual manifestation in a long bone.

    abstract::Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings and regional cervical lymphadenopathy. The disease is more often described from oriental literature but the osseous manifestations and involvement of extremity are rare and unidentified in literature. We present an...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.07.020

    authors: Varshney MK,Kumar A,Khan SA,Yadav CS

    更新日期:2008-07-01 00:00:00

  • Parkinson's disease: A risk factor for osteoporosis.

    abstract::Parkinson's disease is the most common neurodegenerative disease after Alzheimer's disease. On the long term, it may be complicated by various musculoskeletal problems, such as osteoporotic fractures, that have significant socioeconomic consequences. Indeed, patients suffering from Parkinson's disease have a higher fr...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2015.03.009

    authors: Malochet-Guinamand S,Durif F,Thomas T

    更新日期:2015-12-01 00:00:00

  • French recommendations for osteoporosis prevention and treatment in patients with prostate cancer treated by androgen deprivation.

    abstract::Androgen-deprivation therapy (ADT) in patients with prostate cancer can be achieved surgically or chemically, notably by prescribing LHRH analogs. Major bone loss occurs rapidly in both cases, due to the decrease in testosterone levels, and can increase the fracture risk. The objective of developing these recommendati...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2018.09.017

    authors: Briot K,Paccou J,Beuzeboc P,Bonneterre J,Bouvard B,Confavreux CB,Cormier C,Cortet B,Hannoun-Lévi JM,Hennequin C,Javier RM,Lespessailles E,Mayeur D,Mongiat Artus P,Vieillard MH,Debiais F

    更新日期:2019-01-01 00:00:00

  • Rosuvastatin inhibits spontaneous and IL-1β-induced interleukin-6 production from human cultured osteoblastic cells.

    abstract:OBJECTIVE:Experimental and clinical data suggest that statins may protect bone by inhibiting bone resorption and/or stimulating bone formation. Interleukin-6 (IL-6) is produced by osteoblasts, and potently stimulates osteoclast activation playing a key role in normal bone resorption as well as in post-menopausal and in...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2012.07.007

    authors: Lazzerini PE,Capperucci C,Spreafico A,Capecchi PL,Niccolini S,Ferrata P,Frediani B,Galeazzi M,Laghi-Pasini F

    更新日期:2013-03-01 00:00:00

  • A possible association between Chlamydiae psittacci infection and temporal arteritis.

    abstract::Some arguments are in favor of the role of Chlamydia in the pathogenesis of atherosclerosis and some vasculitis. Illustrating this possible relation, we report the case of a patient developing consecutively a Chlamydia psittacci infection and a temporal arteritis. A 73-year-old woman, with no significant medical histo...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/s1297-319x(00)00205-0

    authors: Bonnet F,Morlat P,Delevaux I,Gavinet AM,Parrens M,Bernard N,Lacoste D,Beylot J

    更新日期:2000-01-01 00:00:00

  • Pain in osteoarthritis. Implications for optimal management.

    abstract::Pain is an ubiquitous symptom in osteoarticular diseases, occurring much more commonly than stiffness or disability. OA of the knee, hand, or hip affects around 20% of adults in various populations and is dramatically increasing in many countries, mostly related to age and obesity, leading to an increased number of pe...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2017.08.002

    authors: Trouvin AP,Perrot S

    更新日期:2018-07-01 00:00:00

  • Posterior spinal epidural abscess: an unusual complication of vertebroplasty.

    abstract:OBJECTIVE:Complications after vertebroplasty are rare. There are few reported infectious complications requiring surgical management such as corpectomy with anterior reconstruction and posterior stabilization, although we have not seen any reports about epidural abscess in the literature. We present a patient in whom p...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2006.01.015

    authors: Söyüncü Y,Ozdemir H,Söyüncü S,Bigat Z,Gür S

    更新日期:2006-12-01 00:00:00

  • Frohse's arcade syndrome revealing sarcoidosic myopathy.

    abstract::We report the first case of an unusual sarcoidosic muscular involvement, complicated with radial nerve palsy. A 58-year-old woman suffering from a mediastinopulmonary sarcoidosis, was admitted for a driving deficit of the hands with a radially deviation during the wrist extension. She had been given a diagnosis of mot...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2011.03.007

    authors: Akasbi N,Tahiri L,Daoudi A,Bendahou M,Harzy T

    更新日期:2011-10-01 00:00:00

  • Mast cells and inflammation.

    abstract::The prominent role for mast cells in the inflammatory response has been increasingly well documented in recent years. Mast cells not only contribute to maintain homeostasis via degranulation and to generate IgE-mediated allergic reactions, but also sit at a major crossroads for both innate and adaptive immune response...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2012.08.013

    authors: Frenzel L,Hermine O

    更新日期:2013-03-01 00:00:00

  • Atherosclerosis and connective tissue diseases.

    abstract::Large increases in mortality related to premature atherosclerosis with coronary artery disease and stroke have been reported in patients with systemic lupus erythematosus (SLE), antiphospholipid syndrome (APLS), or rheumatoid arthritis (RA). Studies found relative risks of 5 for myocardial infarction, 6 to 10 for stro...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/s1297-319x(01)00330-x

    authors: Meyer O

    更新日期:2001-12-01 00:00:00

  • Leflunomide-induced aseptic meningitis.

    abstract::Drug-induced aseptic meningitis is uncommon and occurs primarily in patients with autoimmune disease. We report the first known case of leflunomide-induced aseptic meningitis, in a patient with rheumatoid arthritis. ...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/S1297-319X(03)00127-1

    authors: Cohen JD,Jorgensen C,Sany J

    更新日期:2004-05-01 00:00:00

  • Influence of anti-infliximab antibodies and residual infliximab concentrations on the occurrence of acquired drug resistance to infliximab in rheumatoid arthritis patients.

    abstract:BACKGROUND:Infliximab (IFX) can be immunogenic for humans and lead to the formation of antibodies against IFX (anti-IFX Ab), which could induce acquired IFX resistance. OBJECTIVE:To test whether the presence of anti-IFX Ab and residual circulating IFX levels are associated with acquired IFX resistance in RA. METHODS:...

    journal_title:Joint bone spine

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jbspin.2010.02.021

    authors: Finckh A,Dudler J,Wermelinger F,Ciurea A,Kyburz D,Gabay C,Bas S,physicians of SCQM.

    更新日期:2010-07-01 00:00:00

  • Assessing damage in individual joints in rheumatoid arthritis: a new method based on the Larsen system.

    abstract:OBJECTIVES:To evaluate observer agreement using the Larsen system (LS) and a Modified Larsen system (ML) when assessing individual joints of the hands and wrists in rheumatoid arthritis, and to compare the two systems. To determine the minimally important difference (MID) for the ML. METHODS:Thirty radiographs of hand...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2003.07.009

    authors: Zangger P,Kachura JR,Bombardier C,Redelmeier DA,Badley EM,Bogoch ER

    更新日期:2004-09-01 00:00:00

  • Sodium (18)F-sodium fluoride PET failed to predict responses to TNFα antagonist therapy in 31 patients with possible spondyloarthritis not meeting ASAS criteria.

    abstract:OBJECTIVES:To determine whether (18)F-NaF positron-emission tomography (PET) contributes to the diagnosis of spondyloarthritis and whether observed uptakes predict the response to TNFα antagonist therapy. METHODS:We studied patients who had suspected spondyloarthritis but did not meet ASAS criteria and who were referr...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2015.08.012

    authors: Darrieutort-Laffite C,Ansquer C,Maugars Y,Le Goff B,Bodere F,Berthelot JM

    更新日期:2015-12-01 00:00:00

  • Distal phalangeal brachydactyly and osteosclerosis in a case of secondary hyperparathyroidism.

    abstract::A case of severe hyperparathyroidism (HPT), secondary to chronic renal failure, with massive distal phalangeal osteolysis is reported. After parathyroidectomy, brachydactyly and osteosclerosis of the distal phalanges were observed; the phalanx of the thumbs healed with shortened and sclerotic beaked appearance. These ...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/s1297-319x(03)00023-x

    authors: Franco M,Bendini JC,Blaimont A,Albano L,Dray G,Barrillon D,Jaeger P

    更新日期:2003-03-01 00:00:00

  • Detection of a lumbar foraminal venous varix by Color Doppler Ultrasound.

    abstract::Ultrasonography is currently widely used in the rheumatology practice. Although mainly performed to study peripheral joint, several articles have underlined its interest to study spinal anatomy. However, its ability to provide diagnostic features is unknown. We studied the case of a 25-year-old woman having low back p...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2015.09.009

    authors: Darrieutort-Laffite C,Desal H,Berthelot JM,Le Goff B

    更新日期:2016-07-01 00:00:00

  • New factors controlling bone remodeling.

    abstract::Two factors of crucial importance in bone cell differentiation were discovered within the last two years. One is the transcription factor Osf2/Cbfa1, which allows mesenchymal stem cells to differentiate into osteoblasts. Soluble factors, including bone morphogenetic proteins (BMPs), leptin, and TGF-beta, can modulate ...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:

    authors: Marie P,Debiais F,Cohen-Solal M,de Vernejoul MC

    更新日期:2000-01-01 00:00:00

  • Multiple vertebral osteonecrosis.

    abstract::Vertebral osteonecrosis classically presents with an intravertebral vacuum cleft phenomenon or a fluid-filled cleft on MR images. These clefts are usually found in older patients presenting with more severe fractures, more significant collapse and instability. Therefore, although considered for a long time as pathogno...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.05.010

    authors: Javier RM,Moser T,Dietemann JL,Sparsa L,Natarajan-Ame S,Chenard MP,Kuntz JL

    更新日期:2008-05-01 00:00:00

  • Hip pain from impingement and dysplasia in patients aged 20-50 years. Workup and role for reconstruction.

    abstract::In the 20-50-year age group, hip pain usually indicates dysplasia. Chronic mechanical pain is the usual pattern, although acute pain caused by avulsion or degeneration of the labrum may occur. The morphological characteristics of the dysplastic hip should be evaluated, and the link between the dysplasia and the osteoa...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2006.09.001

    authors: Langlais F,Lambotte JC,Lannou R,Gédouin JE,Belot N,Thomazeau H,Frieh JM,Gouin F,Hulet C,Marin F,Migaud H,Sadri H,Vielpeau C,Richter D

    更新日期:2006-12-01 00:00:00

  • Current role for radioisotope synovectomy.

    abstract::Radioisotope synovectomy has been extensively used to treat patients with chronic inflammatory joint disease but has moved to a less prominent position since the introduction of new and highly effective drugs. Remaining indications are refractory synovitis, pigmented villonodular synovitis as an adjunct to surgery, an...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2017.06.002

    authors: André V,Dalibard V,Dernis E,Varin S,Cormier G

    更新日期:2018-05-01 00:00:00

  • Clinical and functional status in 88 rheumatoid arthritis patients followed for 15 years or more by office-based (n = 41) or hospital-based (n = 47) physicians.

    abstract:OBJECTIVE:To determine the very long-term clinical and functional outcomes in rheumatoid arthritis (RA) patients followed by office-based or hospital-based physicians. PATIENTS AND METHODS:A questionnaire including items on clinical outcomes (active disease, remission, burn-out) and the Health Assessment Questionnaire...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/s1297-319x(02)00370-6

    authors: Laborie Y,Berthelot JM,Alliaume C,Baron J,Caumon JP,Desmas V,Rossard A,Maugars Y,Prost A

    更新日期:2002-03-01 00:00:00

  • Monitoring of bone turnover markers does not improve persistence with ibandronate treatment.

    abstract:OBJECTIVE:To assess if the use of biological marker of bone resorption (CTX) feedback is a mean to improve persistence on monthly oral ibandronate. METHODS:One year prospective multicenter study using a cluster randomisation design with physicians as randomized units into two groups, A and B; in group B, physicians us...

    journal_title:Joint bone spine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jbspin.2011.05.001

    authors: Roux C,Giraudeau B,Rouanet S,Dubourg G,Perrodeau E,Ravaud P

    更新日期:2012-07-01 00:00:00

  • Defining treatment failure in severe osteoporosis.

    abstract::The management of postmenopausal osteoporosis has benefited from the recent introduction of several new drug classes and is now well standardized. However, none of the available osteoporosis drugs completely abolishes the occurrence of fractures. Therefore, criteria are needed to determine when the occurrence of a fra...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/S1297-319X(10)70008-7

    authors: Confavreux CB,Paccou J,David C,Mehsen N,Leboime A,Thomas T

    更新日期:2010-12-01 00:00:00

  • Anthropometry at birth as a strong determinant factor of young women bone status: influence of high-level physical activity.

    abstract:OBJECTIVE:To analyze the influence of anthropometry at birth on bone status and physical activity aptitudes of adult women. METHODS:Our population was composed of 70 women (17-29 years): 40 athletes and 30 controls. Athletes participated in various long-lasting and high-level weight-bearing sports (10.2 ± 2.2h ours/we...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2010.07.020

    authors: Bréban S,Chappard C,Jaffré C,Briot K,Benhamou CL

    更新日期:2011-03-01 00:00:00

  • Comparison of the Big Five personality traits in fibromyalgia and other rheumatic diseases.

    abstract:INTRODUCTION:The personality of patients with fibromyalgia is still under debate. Some studies found high neuroticism associated with low extraversion, while others found that these traits do not differ from the normal population. Personality factors intervene in the emotional regulation and modulation of pain. The aim...

    journal_title:Joint bone spine

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jbspin.2016.03.006

    authors: Bucourt E,Martaillé V,Mulleman D,Goupille P,Joncker-Vannier I,Huttenberger B,Reveillere C,Courtois R

    更新日期:2017-03-01 00:00:00

  • Development of temporomandibular joint arthritis: The use of animal models.

    abstract::Osteoarthritis is the most common joint disease affecting roughly one sixth of the human population. It is also the most common arthritis affecting the temporomandibular joint, often leading to severe pain and the inability to masticate. Animal models are essential to investigate the disease in part because they lend ...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2016.05.016

    authors: Ghassemi Nejad S,Kobezda T,Tar I,Szekanecz Z

    更新日期:2017-03-01 00:00:00

  • Exacerbation of interstitial lung disease during etanercept therapy: Two cases.

    abstract::We report two cases of interstitial lung disease possibly related to TNF alpha antagonist therapy (etanercept) in patients with rheumatoid arthritis. In both cases, pre-existing interstitial lung disease worsened during etanercept therapy. We found 19 previously published cases of interstitial lung disease in patients...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2007.04.028

    authors: Tournadre A,Ledoux-Eberst J,Poujol D,Dubost JJ,Ristori JM,Soubrier M

    更新日期:2008-03-01 00:00:00