Role of breast magnetic resonance imaging in determining breast as a source of unknown metastatic lymphadenopathy.

Abstract:

BACKGROUND:Occult primary breast cancer (OPBC) represents less than 1% of breast cancer. In only a third of cases, mammography identifies a primary tumor. We hypothesized that rotating delivery of excitation off-resonance breast magnetic resonance imaging (MRI) would identify or exclude the breast as a primary site in patients with OPBC. METHODS:In a retrospective review, 10 patients were identified with OPBC in which MRI was performed. Malignant appearing lesions were correlated with histopathologic findings at biopsy or surgery. RESULTS:MRI identified the primary site in 8 of 10 cases as breast (80%), and excluded it in 2 cases. The extent of disease and location was accurately predicted when compared with histopathologic specimen. CONCLUSIONS:As we continue to focus on a cure of early breast cancer, it is imperative that diagnostic images become more sensitive and specific. MRI accurately predicted OPBC in this subset of patients.

journal_name

Am J Surg

authors

Henry-Tillman RS,Harms SE,Westbrook KC,Korourian S,Klimberg VS

doi

10.1016/s0002-9610(99)00221-4

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

496-500

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(99)00221-4

journal_volume

178

pub_type

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