Prospective Comparison of Patient Characteristics and Outcome of Non-prior Aspirin Users versus Aspirin Users with Unstable Angina or Non-Q-Wave Myocardial Infarction Treated with Combination Antithrombotic Therapy.

Abstract:

:The objective of this study was to determine if aspirin users presenting with acute coronary syndromes are at higher risk for subsequent clinical events. In a trial evaluating combination antithrombotic therapy in resting angina or non-Q-wave myocardial infarction (MI), patients were prospectively dichotomized on admission into nonprior versus recent aspirin users. Then 105 nonprior users and 144 users were randomized to treatment with aspirin plus heparin/warfarin for 12 weeks. Recurrent myocardial ischemia occurring during the 12-week follow-up period was defined as recurrent angina (with electrocardiographic changes or prompting coronary revascularization), MI, or death. Prior aspirin users had a significantly higher incidence of previous MI, prior bypass grafting, beta-blocker use, or hypertension (p

journal_name

J Thromb Thrombolysis

authors

Cohen M,Adams PC,McBride R,Blanke H,Fuster V V

doi

10.1023/a:1008855220129

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

275-280

issue

2

eissn

0929-5305

issn

1573-742X

journal_volume

4

pub_type

杂志文章
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    authors: Perren F,Loulidi J,Poglia D,Landis T,Sztajzel R

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  • Ultrastructure of a late-stage bacterial endocarditis valve vegetation.

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    authors: Baudoin JP,Camoin-Jau L,Prasanth A,Habib G,Lepidi H,Hannachi N

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  • Acquired thrombotic thrombocytopenic purpura: puzzles, curiosities and conundrums.

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    doi:10.1007/s11239-010-0517-x

    authors: Mar N,Mendoza Ladd A

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  • A pulmonary embolism response team (PERT) approach: initial experience from the Cleveland Clinic.

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    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-018-1686-2

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    更新日期:2018-08-01 00:00:00

  • Monitoring of low dabigatran concentrations: diagnostic performance at clinically relevant decision thresholds.

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    journal_title:Journal of thrombosis and thrombolysis

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    更新日期:2020-04-01 00:00:00

  • Von Willebrand factor with increased binding capacity is associated with reduced platelet aggregation but enhanced agglutination in COVID-19 patients: another COVID-19 paradox?

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    authors: Ruberto F,Chistolini A,Curreli M,Frati G,Marullo AGM,Biondi-Zoccai G,Mancone M,Sciarretta S,Miraldi F,Alessandri F,Ceccarelli G,Barone F,Santoro C,Alvaro D,Pugliese F,Pulcinelli FM,Policlinico Umberto I COVID-19 Group.

    更新日期:2021-01-02 00:00:00

  • Novel sila-amide derivatives of N-acetylcysteine protects platelets from oxidative stress-induced apoptosis.

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    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-016-1450-4

    authors: Paul M,Thushara RM,Jagadish S,Zakai UI,West R,Kemparaju K,Girish KS

    更新日期:2017-02-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1007/s11239-010-0514-0

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    更新日期:2010-11-01 00:00:00

  • Soluble E-selectin is not a marker of unstable coronary plaque in serum of patients with ischemic heart disease.

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    pub_type: 杂志文章

    doi:10.1023/a:1018656530541

    authors: Galvani M,Ferrini D,Ottani F,Nanni C,Ramberti A,Amboni P,Iamele L,Vernocchi A,Nicolini FA

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  • Structure-function relationships of factor Xa inhibitors: implications for the practicing clinician.

    abstract::The recent development and approval of novel oral anticoagulants represents a significant success in the intelligent design of target-specific therapeutics. However, while these agents obviate many of the shortcomings of their predecessor (warfarin), they present novel challenges in pharmacologic management as well. E...

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    pub_type: 杂志文章,评审

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    authors: Steinberg BA,Becker RC

    更新日期:2014-01-01 00:00:00

  • Rivaroxaban in the Treatment of Heparin-Induced Thrombocytopenia.

    abstract::Heparin-induced thrombocytopenia (HIT) is a prothrombotic condition and it is associated with increased in vivo thrombin generation that needs to be treated with non-heparin anticoagulants such as direct thrombin inhibitors (DTIs). DTIs require parenteral administration and are associated with a non negligible risk of...

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    pub_type: 杂志文章

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    更新日期:2020-06-27 00:00:00

  • Implementation of automatic data extraction from an enterprise database warehouse (EDW) for validating pediatric VTE decision rule: a prospective observational study in a critical care population.

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    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

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    更新日期:2020-11-01 00:00:00

  • Thromboembolic events in patients with severe inherited fibrinogen deficiency.

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    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,多中心研究

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    authors: Rottenstreich A,Lask A,Schliamser L,Zivelin A,Seligsohn U,Kalish Y

    更新日期:2016-08-01 00:00:00

  • Treatment of Deep Vein Thrombosis with Low Molecular Weight Heparin at Patient's Home.

    abstract::We have applied the low molecular weight heparin dalteparin as once-daily subcutaneous injections to the treatment of deep vein thrombosis (DVT) on an outpatient basis since 1994. Until today, 377 consecutive patients with DVT below the inguinal ligament have been treated at home with dalteparin. The patients administ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1023/A:1008866025015

    authors: Stockelberg D,Hansson E,Jonson T

    更新日期:1998-09-01 00:00:00

  • Inhibition of collagen, and thrombin-induced platelet aggregation by Lansberg's hognose pit viper (Porthidium lansbergii hutmanni) venom.

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    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-007-0040-x

    authors: López-Johnston JC,de Bosch N,Scannone H,Rodríguez-Acosta A

    更新日期:2007-12-01 00:00:00

  • The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia.

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    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-007-0010-3

    authors: Olivecrona GK,Götberg M,Harnek J,Jacobson KA,Jern S,Erlinge D

    更新日期:2007-10-01 00:00:00

  • D-Dimer elevation and adverse outcomes.

    abstract::D-Dimer is a biomarker of fibrin formation and degradation. While a D-dimer within normal limits is used to rule out the diagnosis of deep venous thrombosis and pulmonary embolism among patients with a low clinical probability of venous thromboembolism (VTE), the prognostic association of an elevated D-dimer with adve...

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    pub_type: 杂志文章,评审

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    更新日期:2015-01-01 00:00:00

  • Lipid rich plaque, female gender and proximal coronary stent edge dissections.

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    pub_type: 杂志文章,多中心研究,随机对照试验

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  • Prothrombotic gene polymorphisms and plasma factors in young North Indian survivors of acute myocardial infarction.

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    更新日期:2012-08-01 00:00:00

  • Evaluation of a rapid turn-over, fully-automated ADAMTS13 activity assay: a method comparison study.

    abstract::Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy caused by severely reduced activity of the von-Willebrand factor-cleaving protease ADAMTS13, mainly caused by anti-ADAMTS-13 antibodies. Although several test systems for ADAMTS13 measurement exist, long turn-around times hamper...

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  • Successful lysis of intra-cardiac thrombi with streptokinase in patients with renal failure; two case reports and review of the literature.

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    pub_type: 临床试验,杂志文章,随机对照试验

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  • Determination of non-Vitamin K oral anticoagulant (NOAC) effects using a new-generation thrombelastography TEG 6s system.

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    authors: Bliden KP,Chaudhary R,Mohammed N,Muresan AA,Lopez-Espina CG,Cohen E,Raviv G,Doubleday M,Zaman F,Mathew B,Tantry US,Gurbel PA

    更新日期:2017-05-01 00:00:00

  • Anti-coagulant activity of plants: mini review.

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  • Thrombolytic therapy in pregnancy.

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    pub_type: 杂志文章,评审

    doi:10.1007/s11239-006-5709-z

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    pub_type: 杂志文章

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  • The post-thrombotic syndrome: the forgotten morbidity of deep venous thrombosis.

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    更新日期:2006-02-01 00:00:00