Abstract:
:Primate pericentromeric regions recently have been shown to exhibit extraordinary evolutionary plasticity. In this paper we report an additional peculiar feature of these regions that we discovered while analyzing, by FISH, the evolutionary conservation of primate phylogenetic chromosome IX. If the position of the centromere is not taken into account, a relatively small number of rearrangements must be invoked to account for interspecific differences. Conversely, if the centromere is included, a paradox emerges: The position of the centromere seems to have undergone, in some species, an evolutionary history independent from the surrounding markers. A significant number of additional rearrangements must be proposed to reconcile the order of the markers with centromere position. Alternatively, the evolutionary emergence of neocentromeres can be postulated.
journal_name
Genome Resjournal_title
Genome researchauthors
Montefalcone G,Tempesta S,Rocchi M,Archidiacono Ndoi
10.1101/gr.9.12.1184subject
Has Abstractpub_date
1999-12-01 00:00:00pages
1184-8issue
12eissn
1088-9051issn
1549-5469journal_volume
9pub_type
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