Routine preoperative lymphoscintigraphy is not necessary prior to sentinel node biopsy for breast cancer.

Abstract:

BACKGROUND:This prospective study was performed to ascertain the added benefit of lymphoscintigraphy to a standard method of intraoperative lymphatic mapping and sentinel node biopsy for breast cancer. METHODS:Patients with invasive breast cancer were injected with 99mTc sulfur colloid prior to sentinel node biopsy; preoperative lymphoscintigraphy was then performed in half of the patient population. RESULTS:Sentinel node identification was possible in 45 of 50 patients (90%). All 14 patients (31%) with axillary nodal metastases had at least one histologically positive sentinel node (0% false negative rate). Lymphoscintigraphy revealed sentinel nodes in 17 of the 24 patients (70.8%) imaged. All 17 of these patients had one or more axillary sentinel nodes identified using intraoperative lymphatic mapping. In addition, 5 of 7 patients with a negative preoperative lymphoscintogram had an axillary sentinel lymph node(s) identified intraoperatively. None of the tumors showed drainage to the internal mammary lymph node chain by lymphoscintigraphy despite the fact that there were 5 patients with inner quadrant tumors. There was no significant advantage with respect to sentinel lymph node localization (91.7% versus 88.5%, P = not significant) or false negative rate (0%, both groups, P = not significant) in the group undergoing preoperative lymphoscintigraphy when compared with the patients in whom lymphoscintigraphy was not performed. CONCLUSIONS:Preoperative lymphoscintigraphy adds little additional information to intraoperative lymphatic mapping, and its routine use is not justified.

journal_name

Am J Surg

authors

Burak WE Jr,Walker MJ,Yee LD,Kim JA,Saha S,Hinkle G,Olsen JO,Pozderac R,Farrar WB

doi

10.1016/s0002-9610(99)00088-4

subject

Has Abstract

pub_date

1999-06-01 00:00:00

pages

445-9

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002961099000884

journal_volume

177

pub_type

临床试验,杂志文章
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    更新日期:2007-10-01 00:00:00

  • Association of metabolic syndrome with morbidity and mortality in emergency general surgery.

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  • Sarcoma and Cystosarcoma phyllodes tumors of the breast--a retrospective review of 58 cases.

    abstract::A retrospective review of 58 rare breast neoplasms encountered at the British Columbia Cancer Agency between 1972 and 1992 was undertaken. There were 38 cystosarcoma phyllodes tumors, 6 carcinosarcomas, and 14 other sarcomas. Initial management involved total mastectomy in 37 cases, wide excision in 14, and excision b...

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    doi:10.1016/0002-9610(94)90238-0

    authors: McGregor GI,Knowling MA,Este FA

    更新日期:1994-05-01 00:00:00

  • Pancreatic cysts: a proposed management algorithm based on current evidence.

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  • Carotid body tumor. The Lahey Clinic experience.

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    doi:10.1016/0002-9610(83)90052-1

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    更新日期:1983-04-01 00:00:00

  • Occupational blood-borne diseases in surgery.

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  • Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus.

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    更新日期:2002-03-01 00:00:00

  • Risk of post-procedural bleeding in children on intravenous fish oil.

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  • Surgical treatment of primary carcinoma of the gallbladder based on the histologic analysis of 48 surgical specimens.

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    doi:10.1016/0002-9610(92)90109-5

    authors: Matsumoto Y,Fujii H,Aoyama H,Yamamoto M,Sugahara K,Suda K

    更新日期:1992-02-01 00:00:00

  • Cause and prevention of postherniorrhaphy neuralgia: a proposed protocol for treatment.

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    pub_type: 杂志文章

    doi:10.1016/s0002-9610(88)80044-8

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    更新日期:1988-06-01 00:00:00

  • Obstructing phytobezoar arising from proximal jejunal diverticulum.

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    doi:10.1016/j.amjsurg.2007.02.018

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    更新日期:2008-01-01 00:00:00

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    journal_title:American journal of surgery

    pub_type: 杂志文章

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    更新日期:2015-02-01 00:00:00

  • Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio.

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    pub_type: 临床试验,杂志文章,随机对照试验

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    更新日期:1975-06-01 00:00:00

  • Indications and results for transduodenal sphincteroplasty in the era of endoscopic sphincterotomy.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2009.08.048

    authors: Miccini M,Amore Bonapasta S,Gregori M,Bononi M,Fornasari V,Tocchi A

    更新日期:2010-08-01 00:00:00

  • The effects of ischemia on the electrical and contractile activities of the canine small intestine.

    abstract::The effects of ischemia on the electrical and contractile activites of the small bowel were studied in dogs. Ischemia due to arterial occlusion abolished the contractile activity and made the regular rhythm of the pacesetter potential (PP) irregular. Revascularization within 3 hours restored the contractile activity a...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(78)90237-4

    authors: Cabot RM,Kohatsu S

    更新日期:1978-08-01 00:00:00

  • How medical students define surgical mentors.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2003.12.053

    authors: Cochran A,Paukert JL,Scales EM,Neumayer LA

    更新日期:2004-06-01 00:00:00

  • Serum creatinine and chest radiographs in the early assessment of acute pancreatitis.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(98)00296-7

    authors: Talamini G,Uomo G,Pezzilli R,Rabitti PG,Billi P,Bassi C,Cavallini G,Pederzoli P

    更新日期:1999-01-01 00:00:00

  • Effect of cyclosporin A on hepatocyte proliferation after partial hepatectomy in rats: comparison with standard immunosuppressive agents.

    abstract::The effects of cyclosporin A on the regenerating liver were studied in rats after partial hepatectomy and were compared with those of conventional immunosuppressants such as methylprednisolone and azathioprine. In Group I, a standard hepatectomy removing two thirds of the organ was performed. In Group II, an oral dose...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(88)80705-0

    authors: Kim YI,Salvini P,Auxilia F,Calne RY

    更新日期:1988-02-01 00:00:00

  • Diagnosis of a carotid body chemodectoma with dynamic radionuclide perfusion scanning.

    abstract::The first case of a carotid body chemodectoma that was diagnosed using dynamic radionuclide perfusion angiography and subsequently excised is presented. The value of this technic in the investigation of pulsatile tumors is emphasized. ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(79)90043-6

    authors: Peters JL,Ward MW,Fisher C

    更新日期:1979-05-01 00:00:00

  • Endocrine ablation for metastatic breast cancer: a reappraisal of hormone receptors.

    abstract::Other indicators of hormone sensitivity, besides estrogen receptor (ER) content, such as response to oophorectomy, antiestrogens, prolactin suppression, and correlation with progesterone receptors (PR), were evaluated in the hope of further improving selectivity and response of patients undergoing endocrine ablation f...

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    pub_type: 杂志文章

    doi:10.1016/0002-9610(80)90435-3

    authors: Moseley HS,Peetz ME,Keenan EJ,Awrich AE,Fletcher WS

    更新日期:1980-07-01 00:00:00

  • Selective bowel decontamination in hospitalized patients awaiting liver transplantation.

    abstract:BACKGROUND:Infection remains a major contributor to morbidity and mortality following orthotopic liver transplantation (OLT). Selective bowel decontamination (SBD) in hospitalized patients is one strategy for prophylaxis. METHODS:A retrospective case-control study was performed using 18 consecutive hospitalized patien...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(97)00185-2

    authors: Kuo PC,Bartlett ST,Lim JW,Plotkin JS,Wilson S,Johnson LB

    更新日期:1997-12-01 00:00:00

  • Inhibition of DNA synthesis by somatostatin in rat hepatocytes stimulated by hepatocyte growth factor or epidermal growth factor.

    abstract::The antiproliferative effects of somatostatin on hepatocytes stimulated by hepatocyte growth factor (HGF) or epidermal growth factor (EGF) were investigated using primary cultures of adult rat hepatocytes. Somatostatin inhibits HGF-induced (at a dose of 10 ng/mL) or EGF-induced (at a dose of 100 ng/mL) 3H-thymidine in...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(92)90271-r

    authors: Kokudo N,Kothary PC,Eckhauser FE,Nakamura T,Raper SE

    更新日期:1992-01-01 00:00:00

  • Treatment of chronic visceral ischemia.

    abstract::Herein, we have described the surgical management of 23 patients with chronic intestinal ischemia. The patients presented most commonly with postprandial pain and weight loss. Diagnosis was confirmed by angiography, including lateral aortography. Surgery included bypass with Dacron being the most common graft material...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(84)90301-5

    authors: Baur GM,Millay DJ,Taylor LM Jr,Porter JM

    更新日期:1984-07-01 00:00:00

  • Primary and secondary prevention of gallstone disease: implications for patient management and research priorities.

    abstract::Primary prevention is defined as the prevention of gallstone formation; secondary prevention is defined as the prevention of clinical manifestations of gallstones--symptoms or more severe complications. For primary prevention, general "wellness" measures can be recommended from a theoretic standpoint. These include el...

    journal_title:American journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-9610(05)80958-4

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    更新日期:1993-04-01 00:00:00

  • Giant duodenal hamartoma consisting mainly of Brunner's glands.

    abstract::A successfully treated case of a duodenal hamartoma is presented. A review of the literature has shown that this is the largest such tumor so far described, and the first time a mass was palpable on abdominal examination. Its large size resulted in pyloric obstruction, and its wide attachment to the duodenum necessita...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(77)90090-3

    authors: de Silva S,Chandrasoma P

    更新日期:1977-02-01 00:00:00

  • Investigating the effect of discordant clinical and pathological diagnoses of complicated appendicitis on clinical outcomes.

    abstract:BACKGROUND:Following appendectomy, management is often guided by surgeon determination of whether the appendicitis is uncomplicated or complicated. Our objectives were to determine the incidence of discordance between intraoperative and pathological findings and determine effect on outcomes. METHODS:We performed a ret...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2019.05.004

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  • Assessing compliance with national quality measures to improve colorectal cancer care at the VA.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

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  • Rapid noninvasive optical imaging of tissue composition in breast tumor margins.

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    pub_type: 临床试验,杂志文章

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