Selective bowel decontamination in hospitalized patients awaiting liver transplantation.

Abstract:

BACKGROUND:Infection remains a major contributor to morbidity and mortality following orthotopic liver transplantation (OLT). Selective bowel decontamination (SBD) in hospitalized patients is one strategy for prophylaxis. METHODS:A retrospective case-control study was performed using 18 consecutive hospitalized patients receiving SBD prior to OLT during the period September 1995 to September 1996. Eighteen consecutive hospitalized patients without SBD transplanted during the period March 1995 to September 1995 served as a historical control group. RESULTS:Selective bowel decontamination was associated with a significantly decreased prevalence of positive cultures for gram-negative bacteria and fungi and reduced overall hospital charges. CONCLUSION:In hospitalized patients awaiting OLT, SBD is an effective prophylactic measure against infectious morbidity associated with gram-negative bacteria and fungi.

journal_name

Am J Surg

authors

Kuo PC,Bartlett ST,Lim JW,Plotkin JS,Wilson S,Johnson LB

doi

10.1016/s0002-9610(97)00185-2

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

745-8; discussion 749

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002961097001852

journal_volume

174

pub_type

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