Abstract:
:The effect of the addition 0.3% triclosan to a non-fluoride and fluoride toothpaste was tested in an in vitro demineralisation model. This model comprised bovine dentin specimens overlaid with acidogenic Streptococcus mutans suspensions in agarose at two different concentrations of cells. Before the experiments, subsurface lesions were made in the dentin specimens in a methylcellulose gel system. In a first set of experiments, the toothpastes were diluted in the S. mutans suspensions at w/v dilutions of 1:100, 1:1,000, and 1:10,000, respectively. After 22 h of incubation at 37 degrees C, the suspensions were removed and assessed for calcium, lactate and pH. In this set of experiments, an additive protective effect of triclosan to the non-fluoride toothpaste was found at the lowest concentration of S. mutans cells and when the toothpaste was relatively undiluted (1:100 w/v). No additive effect was observed to the fluoride toothpaste. In the second set of experiments, the specimens were immersed daily for 3 min in 30% (w/v) slurries of the toothpastes before the 22-h incubations with the S. mutans suspensions. At the lowest concentration of S. mutans cells, triclosan had an additional protective effect to the non-fluoride and fluoride toothpaste. It is concluded that triclosan may contribute to the protection of dentin under a mild acid attack both when it is present in dental plaque and when it has been adsorbed to the dentin.
journal_name
Eur J Oral Scijournal_title
European journal of oral sciencesauthors
van Loveren C,Buijs JF,ten Cate JMdoi
10.1046/j.0909-8836.1999.eos107207.xsubject
Has Abstractpub_date
1999-04-01 00:00:00pages
114-20issue
2eissn
0909-8836issn
1600-0722journal_volume
107pub_type
杂志文章abstract::The conditions under which mechanical properties of dentine are tested influence the values recorded. The aims of this study were to examine the effect of hydration on the mechanical properties of primary carious dentine and to provide information on changes in hardness and modulus of elasticity change caused by the d...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.2004.00123.x
更新日期:2004-06-01 00:00:00
abstract::This study investigated the capacity of macrophages exposed to gutta-percha particles to produce factors affecting bone metabolism. Peritoneal mouse macrophages were isolated and incubated with and without gutta-percha particles, and the supernatants were assessed for bone resorbing activity by adding macrophage-condi...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1046/j.0909-8836.1998.eos106406.x
更新日期:1998-08-01 00:00:00
abstract::The goals of this study were to investigate whether (i) muscle activities are affected by different feedback strategies, (ii) the balancing behavior of the neuromuscular system is influenced by different force levels, and (iii) axial loading of the posterior teeth is a realistic biomechanical conception. In 10 healthy...
journal_title:European journal of oral sciences
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doi:10.1111/j.1600-0722.2008.00537.x
更新日期:2008-06-01 00:00:00
abstract::The aim of the present investigation was to map the presence of prophylactic measures in organized Swedish dental health care systems, focusing on personnel working with children and adolescents. The study was conducted by sending a questionnaire to all public dental clinics in Sweden (830 clinics in all). The results...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.1996.tb00115.x
更新日期:1996-08-01 00:00:00
abstract::Substantial evidence exists to suggest a role for T-cells in periodontal disease. As yet, however, the T-cell receptors remain to be characterised at the molecular level. The expression and the nucleotide sequence of genes from the T-cell receptor beta variable (TCRBV) gene families 2, 6 and 8 were analyzed in periodo...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.1997.tb02136.x
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abstract::The expression of HLA Class II antigens on the surfaces of immunocompetent cells and the presence of CD1a+ cells (Langerhans cells) are important components of antigen presentation. Quantitative variations in HLA class II expression on antigen-presenting cells play a role in immune regulation. An indirect immunofluore...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.1995.tb00161.x
更新日期:1995-08-01 00:00:00
abstract::The objective of this study was to obtain a geographic world map of scientific production in dentistry by analysing published papers. Articles and reviews in the Dentistry, Oral Surgery & Medicine category published from 1999 to 2003 were accessed through the ISI database. The data were analyzed quantitatively (number...
journal_title:European journal of oral sciences
pub_type: 杂志文章
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abstract::The principles of formation, renewal, and eruption of teeth are discussed. Numerous genetic aberrations may affect the formation and eruption of teeth. Cleidocranial dysplasia (CCD), caused by mutations in the runt-related transcription factor 2 (RUNX2) gene, is such a condition. The dental phenotype includes problems...
journal_title:European journal of oral sciences
pub_type: 杂志文章,评审
doi:10.1111/eos.12418
更新日期:2018-10-01 00:00:00
abstract::A derivative (EMD) of enamel matrix proteins (EMPs) is used for periodontal regeneration because EMPs are believed to induce the formation of acellular extrinsic fiber cementum (AEFC). Other reports, however, indicate that EMPs have osteogenic potential. The aim of this study was to characterize the nature of the tiss...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.2006.00300.x
更新日期:2006-05-01 00:00:00
abstract::The levels of salivary mutans streptococci and caries experience were used as predictors for caries incidence in 3 groups of pre-school children from areas with different levels of natural and topical fluoride exposure. Altogether 1022 children, 4-5 years of age at baseline, were examined according to the WHO-criteria...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.1996.tb00136.x
更新日期:1996-10-01 00:00:00
abstract::There is evidence that the quantity of antigen load is crucial for the activation of IgA immune responses. In order to investigate the relevance of these findings in aggressive periodontitis, salivary antibody responses were measured during non-surgical and antibiotic treatment. Twenty-one patients with generalized ag...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1034/j.1600-0722.2003.00040.x
更新日期:2003-06-01 00:00:00
abstract::Plasma arc light units for curing resin composites have been introduced with the claim of relatively short curing times. The purpose of the present study was to measure and compare elution of monomers from an experimental BisGMA-TEGDMA resin and a commercial resin composite when cured with a halogen unit and when cure...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1034/j.1600-0722.2000.108004341.x
更新日期:2000-08-01 00:00:00
abstract::Coadhesion between oral microbial pairs is an established factor in the spatiotemporal development and prevalence of mixed-species communities in early dental plaque in vivo. This study compares removal and de novo adhesion of pairs of coadhering and non-coadhering oral actinomyces and streptococci by sonic brushing o...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.0909-8836.2003.00078.x
更新日期:2003-12-01 00:00:00
abstract::Immunoexpression of the extracellular matrix (ECM) proteins laminin, fibronectin, tenascin and types I, III and IV collagen was analyzed in the major and minor salivary glands of seven human fetuses at different gestational ages. The results showed the presence and localization of laminin, collagen IV and fibronectin ...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.2004.00169.x
更新日期:2004-12-01 00:00:00
abstract::We examined the effect of warm air-drying on the enamel bond strengths and the surface free-energy of three single-step self-etch adhesives. Bovine mandibular incisors were mounted in self-curing resin and then wet ground with #600 silicon carbide (SiC) paper. The adhesives were applied according to the instructions o...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/eos.12061
更新日期:2013-08-01 00:00:00
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journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.2009.00704.x
更新日期:2010-02-01 00:00:00
abstract::RhoA plays a fundamental role in regulation of the actin cytoskeleton, intercellular attachment, and cell proliferation. During amelogenesis, ameloblasts (which produce the enamel proteins) undergo dramatic cytoskeletal changes and the RhoA protein level is up-regulated. Transgenic mice were generated that express a d...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/eos.12059
更新日期:2013-08-01 00:00:00
abstract::Axonal regeneration of the inferior alveolar nerve (IAN) is a therapeutic target for functional recovery after peripheral nerve injury. Rifampicin exerts anti-apoptotic, anti-inflammatory, and anti-oxidant effects on nerve tissues that may enhance functional recovery after peripheral nerve injury. The aim of the prese...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/eos.12691
更新日期:2020-06-01 00:00:00
abstract::To investigate change in oral health in relation to use of dental services, a random sample of 45- to 54-yr-old subjects from Adelaide, South Australia, was surveyed in 2004-2005 (n = 986, response rate = 44.4%). Service use and a global oral-health transition (GOHT) statement were collected over 2 yr. Worsening in or...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.2012.00985.x
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abstract::The objective of this study was twofold, namely to evaluate the effectiveness of a dental clinical practice guideline on the management of asymptomatic impacted lower third molars (i) on referral rates and (ii) on dentists' change in knowledge. A two-arm cluster randomized controlled trial, with pre- and post-test ass...
journal_title:European journal of oral sciences
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abstract::Plaque surface area after rinsing with a tea, containing low levels of fluoride, was evaluated in 30 human volunteers with a single-blind, one-operator, three-period, three-treatment cross-over study. The mouthwashes employed were: (1) tea (Darjeeling first flush:< 0.2 ppm F-), (2) Meridol(R), (3) control (tap water:<...
journal_title:European journal of oral sciences
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1995-12-01 00:00:00
abstract::It was the purpose of this article to analyze the (micro) morphological structure of enamel at different stages of development in order to deduce movement patterns of ameloblasts during formation of the human dental primordium. Developing enamel and overlying ameloblasts were dried and fractured for scanning electron ...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.2006.00314.x
更新日期:2006-05-01 00:00:00
abstract::To test the hypothesis that the astrocytic chemokine (C-C motif) ligand 2 (CCL2) plays an important role in nocifensive behaviors after experimental tooth movement (ETM), the expression and cellular localization of CCL2 and astrocyte activation in the medullary dorsal horn (MDH) were determined by immunohistochemistry...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/eos.12099
更新日期:2014-02-01 00:00:00
abstract::The aim of this study was to investigate the effect of polymerization time and polymerization temperature on the residual methyl methacrylate (MMA) content of two heat-cured and two autopolymerized denture base polymers. Gas chromatography was used to determine the residual MMA content of three test specimens of each ...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1046/j.0909-8836.1998.eos106109.x
更新日期:1998-02-01 00:00:00
abstract::This study evaluated the effect of two desensitizers on inhibition of dentin demineralization, after immersion in artificial saliva using micro-computed tomography (μCT). Dentin blocks cut from bovine incisors were treated with deionized water (DW, a negative control) or one of three desensitizers: a fluoride varnish ...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/eos.12155
更新日期:2014-12-01 00:00:00
abstract::The failure of a certain number of microtensile specimens during their preparation and before loading is a common and undesirable occurrence. This study was aimed at observing, under a scanning electron microscope, enamel and dentin microtensile specimens, in order to find structural faults that might be responsible f...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1034/j.1600-0722.2002.21317.x
更新日期:2002-10-01 00:00:00
abstract::Secretion rates and composition of unstimulated and chewing-stimulated whole saliva and 3% citric acid stimulated parotid and submandibular-sublingual secretions were studied in 12 hypertensive patients during withdrawal of and re-exposure to antihypertensive pharmacotherapy. All the patients' blood pressures were wel...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/j.1600-0722.1996.tb00076.x
更新日期:1996-06-01 00:00:00
abstract::Streptococcus oligofermentans is a novel strain of oral streptococcus that can specifically inhibit the growth of Streptococcus mutans. The aims of this study were to assess the growth of S. oligofermentans and the ability of S. oligofermentans to inhibit growth of Streptococcus mutans at different pH values. Growth i...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1111/eos.12102
更新日期:2014-02-01 00:00:00
abstract::Xylitol reduces plaque but the reduction mechanism is largely unknown. The main aim of the present study was to determine whether the xylitol-induced reduction in the amount of plaque and the number of mutans streptococci could be demonstrated in subjects with (presumably) high levels of xylitol-resistant (XR; not inh...
journal_title:European journal of oral sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0722.1997.tb00196.x
更新日期:1997-04-01 00:00:00
abstract::Enamelysin is a matrix metalloproteinase (MMP-20) secreted by ameloblasts, previously shown to hydrolyze recombinant amelogenin. The purpose of this study was to use recombinant MMP-20 to further investigate the specific hydrolysis of peptide fragments containing cleavage sites for tyrosine-rich amelogenin peptide (TR...
journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1046/j.0909-8836.1999.eos107506.x
更新日期:1999-10-01 00:00:00