Nesidioblastosis with hyperinsulinemic hypoglycemia in adults: report of two cases.

Abstract:

:We report herein the cases of two women, aged 34 years and 39 years, respectively, found to have hyperinsulinemic hypoglycemia after presenting with a history of episodes of temporary loss of consciousness, nausea, and fainting. Under the suspected diagnosis of insulinoma, localization procedures were carried out, but no tumor was found. In both patients, a definite gradient in insulin concentration was found in the pancreas by percutaneous transhepatic or intraoperative portal venous sampling, and a misdiagnosis of insulinoma of the pancreatic body was made. During exploratory laparotomy no tumor was palpable in the pancreas, and intraoperative ultrasonography showed no low echoic mass in the pancreas. A distal pancreatectomy was performed in both patients, and histopathological examination of the resected specimens revealed graded slight hyperplasia of the islet cells.

journal_name

Surg Today

journal_title

Surgery today

authors

Eriguchi N,Aoyagi S,Hara M,Tanaka E,Hashimoto M,Jimi A

doi

10.1007/BF02483064

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

361-3

issue

4

eissn

0941-1291

issn

1436-2813

pii

10.1007/BF02483064

journal_volume

29

pub_type

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