Abstract:
PURPOSE:The anatomical site of resected lobes may influence postoperative cerebral infarction. The objective of the current study was to determine if left upper pulmonary lobectomy is a risk factor for postoperative cerebral infarction. METHODS:This was a retrospective case-control study in patients undergoing pulmonary lobectomy from 2004 to 2013 in Japan. We retrospectively identified 610 patients from 153 institutions who had developed postoperative cerebral infarction following pulmonary lobectomy. The control group consisted of 773 patients who underwent lobectomy without cerebral infarction during a randomly selected single month in 2009 at the same institutions. RESULTS:Factors associated with cerebral infarction were age [10-year intervals, odds ratio (OR): 1.46; 95% confidence interval (CI): 1.23-1.73; p < 0.001], male sex (OR 1.92; 95% CI 1.29-2.86; p = 0.001), presence of comorbidities (OR 1.82; 95% CI 1.35-2.44; p < 0.001), perioperative anti-platelet or anti-coagulant drug use (OR 1.71; 95% CI 1.20-2.45; p = 0.003), and lobectomy. Subgroup analyses revealed that cerebral infarction was strongly associated with left upper lobectomy. CONCLUSIONS:Our findings suggest that left upper lobectomy is associated with a higher risk of cerebral infarction than other types of lobectomy, particularly in the early postoperative period.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Matsumoto K,Sato S,Okumura M,Niwa H,Hida Y,Kaga K,Date H,Nakajima J,Usuda J,Suzuki M,Souma T,Tsuchida M,Miyata Y,Takeshi N,Committee for Patient Safety, Quality Management of Japanese Association for Chest Surgery.doi
10.1007/s00595-020-02032-4subject
Has Abstractpub_date
2020-11-01 00:00:00pages
1383-1392issue
11eissn
0941-1291issn
1436-2813pii
10.1007/s00595-020-02032-4journal_volume
50pub_type
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