Abstract：
BACKGROUND:Delayed graft function is a common and severe complication after cadaveric kidney transplantation. Besides a more complicated postoperative course, DGF can worsen the overall graft survival. In particular, DGF enhances the nephrotoxicity of mainstream immunosuppressants cyclosporine and FK506. This study evaluates a new therapeutical approach to the treatment of DGF related nephrotoxicity, based on the administration of IGF-I. METHODS:Sixty inbred Lewis rats underwent a bilateral clamping of the renal pedicles (20') as standard damage. The animals were stratified in six groups, according to the postoperative treatment. Group 1 served as control and received only the standard ischemic injury. Cyclosporine and FK506 were added in groups 3 and 5. Groups 2, 4 and 6 had the same treatment of groups 1, 3, 5 respectively, plus the administration of IGF-I. Blood samples were drawn daily to evaluate creatinine and BUN for 7 days. RESULTS:The rats treated with IGF-I had significantly better values compared to the respective controls (2-way ANOVA, p < 0.05). CONCLUSIONS:In conclusion, IGF-I improves the nephrotoxicity of mainstream immunosuppressants in this model. Its use is potentially beneficial for transplantation.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Maestri M,Dionigi P,Pettenazza P,Visconti F,Rademacher J,Gaspari A,Innocente F,Matteotti C,Luzzana F,Zonta Asubject
Has Abstractpub_date
1998-05-01 00:00:00pages
391-6issue
5eissn
0026-4733issn
1827-1626journal_volume
53pub_type
杂志文章abstract：BACKGROUND:Surgeon's position during open cholecystectomy operation has been standardized since more than 100 years, being traditionally fixed at the right side of the patient. Only a few French authors adopted the "left location" just for the time requested for the common bile duct exploration. METHODS:In this paper ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:Although the common bile duct is now accessed using a coelioscopic approach by an increasing number of surgical equipes, the problems related to the diagnostic iter of lithiasis of the common bile duct and the need to obtain a correct preoperative diagnosis, in order to select the most appropriate form of therapy, are...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：INTRODUCTION:Laparoscopic cholecystectomy now represents a valid alternative to traditional surgery in the treatment of gallstone diseases. For the past twenty years laparotomic cholecystectomy has represented the golden standard of gallstone treatment given its extremely low mortality rate (0.5%) and equally acceptabl...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The authors outline the stages of abdominoperineal surgery due to rectal cancer to achieve the reconstruction of perineal-stomic continence. The operation is simple to perform, without particular vascular risks and sepsis; it does not necessitate temporary abdominal colostomy and, lastly, does not oblige postoperative...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-06-30 00:00:00
abstract：:A case of a young male operated on for acute appendicitis due to a carcinoid of the base is reported. Since the tumor was infiltrating the resection margin of the appendix, the patient was later treated with a right hemicolectomy. Carcinoid tumor is unusual, but can be encountered several times during the career of a ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The Authors perform a retrospective study on the incidence of postoperative jaundice in a selected group of 2060 patients, who underwent operations of general or vascular surgery. The incidence of jaundice in the postoperative period appears to be quite high in vascular surgery: out of 96 patients became jaundiced, 78...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-06-30 00:00:00
abstract：:Mean daily doses of 4-800,000 units iant. Cal. Trasylol administered i.v. for about 7 days prevented oedema and improved circulation after revascularisation surgery of the lower extremities involving the femoropopliteal axis in a large number of clinical cases. ...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：1975-02-15 00:00:00
abstract：:Forty-nine consecutive patients with early gastric cancer (EGC), observed from January 1978 to December 1992 in the Surgery Department of our Institute, were included in a retrospective study. The EGC prevalence in the overall cases of gastric cancer was 11%. This frequency was 8% in the period 1978-1985 and 15% in th...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：INTRODUCTION:Surgical management of external rectal prolapse (ERP) remains a challenge with the breadth of choices available and varies on the international, national, regional and locoregional level. Significant innovation has led to new techniques to manage ERP including changes to both abdominal and perineal approac...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4733.16.07205-9
更新日期：2017-02-01 00:00:00
abstract：:Following and exhaustive review of the literature on this topic, the paper reports the results of the treatment of 16 patients with male breast cancer. From an analysis of findings, it was observed that diagnosis is frequently delayed (mean 1 year), disease is at a locally advanced stage in the majority of patients, a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：AIMS AND BACKGROUND:Helicobacter pylori is known to be the pathogenic agent of atrophic gastritis and above all ulcer disease. It is also thought to play a role, together with other factors, in the development of stomach cancer and is currently the focus of numerous studies. In industrialised countries, infection is re...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:Double pylorus is an extremely rare pathology: it can be an acquired or congenital lesion. Two new cases complicating a peptic ulcer are reported and the clinical appearance and evolution of the different etiological type are described. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：:This report describes 51 vascular patients with peripheral vascular disease treated intraoperatively by means of the autotransfusion apparatus with a minimum of 750 cc of reinfused blood. An early decrease of Hct, Hb, RBC, fibrinogen and Plt count was observed without any significant coagulation disorder. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:The incidence of thyroid cancer has increased dramatically, yet the mortality has remained unchanged. There remain many challenges and "difficult problems" in diagnosing and treating patients with differentiated thyroid cancer (DTC). A significant percentage of patients with DTC will present with a thyroid nodule and ...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2010-02-01 00:00:00
abstract：:A multicentre study has been done to evaluate the effectiveness and safety of pefloxacin, a new fluoroquinolone, when given intravenously for surgical prophylaxis. 440 patients (224 males, 216 females), mean age 51.7 +/- 27.3 (SD) years and mean weight 68.4 +/- 12.6 kg, were admitted to the study. The diagnoses for ad...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1994-10-01 00:00:00
abstract：:The early surgical reexploration to check the viability of intestinal loops in patients operated on for acute mesenteric ischaemia (the so called "second-look"), has contributed in improving the prognosis of this disease. However, since there are no certain predictive criteria for the progression of ischaemia, and not...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
abstract：:H2 blockers have accelerated the reduction in elective peptic ulcer surgery but appear to have had no equivalent effect on the incidence of perforated ulcer success. A 13 year (1975-1987) review of perforated peptic ulcer is presented. The mean annual number of operations for perforation fell from 8.21% to 4.93% after...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-11-15 00:00:00
abstract：:Clinical, radiological and endoscopic results at follow-up about 1-5 yr after surgery in a series of 62 patients subjected to Billroth I resection are compared with those in the literature. Recurrence of ulcers was observed in 8% (as opposed to 5% with the Billroth II). In addition, there was a marked reduction in the...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-07-15 00:00:00
abstract：:In Italy 250,000 subjects every year are affected by malignant tumors, causing 150,000 deaths/year. The global index (statistic prevalence) of oncological patients, either at first diagnosis, or restored to health or under treatment, aggregates 1 million and 500 thousand individuals. During his whole lifetime, every m...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
abstract：:Among 94 cases of pulmonary metastases treated by the exeresis of one or more nodules, 28 cases produced metastasis located in the lung only. Radical metastasectomy was performed on 250. Analysis of survival, also assessed in relation to every prognostic factor reveals the efficacy of surgical therapy even in iterativ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-09-30 00:00:00
abstract：:Attention is drawn to the fact that renal transplants are quite commonly complicated by stenosis of the arterial pedicle. The symptomatology (hypertension, oliguria, fever and gradual loss of renal function) points to the need for angiography. In about 70% of cases, surgical management in the light of the nature of th...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-08-15 00:00:00
abstract：:The Authors present their personal experience in the surgical treatment, using the Shouldice modified method, of 85 cases of patients suffering from inguinal hernia. The rarity of general and local complications and the relatively low percentage of relapse, if compared with other surgical methods, testify to the valid...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：BACKGROUND:The authors describe the advantages and disadvantages of plastic surgery performed in a day-care public hospital unit. METHODS:A retrospective study was made of the day-surgery activities over 16 months (1998-1999) as part of a centralized system. Data were compared to day-surgery activities undertaken in 1...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Successful closure of a iatrogenic tracheoesophageal fistula by means of bronchoscopic application of fibrin glue in a 77-year old patient is reported. The fistula was completely obliterated after a single application of the glue, with resolution of the clinical and radiological signs. The procedure may be suggested a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-10-15 00:00:00
abstract：:A typical case of spontaneous rupture of the oesophagus (Boerhaave's syndrome) successfully operated at the Surgery Division of the Lodi Greater Hospital is presented. An account of the aetiopathogenetic, anatomopathological and clinical problems involved is followed by an examination of the possibilities of diagnosis...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1975-10-15 00:00:00
abstract：:The authors describe the application of Nissen-Rossetti fundoplication for the treatment of hiatus hernia using a laparoscopic approach. They report excellent results both immediately after surgery and in the medium term. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:Reference is made to a personal case in an examination of the more controversial aspects of segmentary necrosis of the main bile pathway. Attention is drawn to the leading features of the pathogenetic evolution of this lesion. Bearing in mind the almost insurmountable difficulty of formulating a preoperative diagnosis...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-05-31 00:00:00
abstract：:A case of entero-vesical fistula in Crohn's disease is presented. Clinical manifestations, diagnostic means and surgical treatment of the lesion are discussed. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Mucinous cystadenocarcinoma of the cecal appendix is a very rare malignant neoplasia. The majority of these tumours are discovered during surgery performed for other pathologies or as a chance finding in the histological analysis of surgically removed inflamed appendix. There is no characteristic symptomatology of thi...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Videolaparoscopic cholecystectomy is considered the treatment of choice for simple cholelithiasis. Now many surgeons consider the laparscopic procedure usable also in the complicated biliary lithiasis like acute cholecystitis and choledocholithiasis. The authors report their recent experience of the laparoscopic treat...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
