Abstract:
:A multicentre study has been done to evaluate the effectiveness and safety of pefloxacin, a new fluoroquinolone, when given intravenously for surgical prophylaxis. 440 patients (224 males, 216 females), mean age 51.7 +/- 27.3 (SD) years and mean weight 68.4 +/- 12.6 kg, were admitted to the study. The diagnoses for admission included several surgically treated specialties (obstetrics and gynecology, orthopedics and traumatology, oncology and general surgery). Pefloxacin was provided in 5 ml ampoules containing 400 mg of active principle to administer by slow intravenous perfusion (1 hour) diluted in 5% glucose solution. The multicentre study was open and non-comparative. The physician could choose between two different dosage schedules to use for surgical prophylaxis. The ultrashort schedule consisted of treatment with 2 ampoules (800 mg), given in the hour before the operation (followed for 217 cases). The short schedule consisted of 2 ampoules (800 mg) given in the hour before the operation, another 2 ampoules 12 hours after surgery and 2 ampoules 24 hours after the surgery (followed for 223 cases). The prophylaxis with pefloxacin was effective, with control of the temperature, the ESR and wound healing in the post-operative period. The surgical wounds of 11.4% of cases (50/440) were erythematous and infiltrated on the 2nd day, and of 14.8% of cases (65/440) on the 3rd day, and then became normal on the next few days. 24 patients had infections after the operation, in 15 cases involving the surgical field (3.4%) and in 9 cases being infections of the respiratory or urinary systems.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Leo P,Mangione Ssubject
Has Abstractpub_date
1994-10-01 00:00:00pages
1031-7issue
10eissn
0026-4733issn
1827-1626journal_volume
49pub_type
临床试验,杂志文章,多中心研究abstract::The authors report the own experience about the experimental use of tissue adhesive in the colonic surgery, on 14 rabbits, with quite satisfactory result. Therefore they evince that this tissue adhesive, althought it can't replace the surgical suture, yet it can help the surgeon out of a hard colonic anastomosis. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1980-05-15 00:00:00
abstract::Twenty-two patients undergoing major head and neck surgery were included in a randomized trial to value the efficacy and side effects of parenteral short-term antibiotic prophylaxis of post-operative infections. Two different antibiotic regimens were compared: group A, ceftazidime i.v. (2 g) in three doses (half an ho...
journal_title:Minerva chirurgica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-11-30 00:00:00
abstract::Microscopic examination of organs from outbred and inbred rats used in 5 groups for experiments in parabiosis with and without crossing of the digestive tubes and pseudoparabiosis showed that skin junctions soon became dehiscent, with boundary furrows tendings to separate the animals, in outbred rats, whereas continui...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1976-02-15 00:00:00
abstract:AIMS AND BACKGROUND:Helicobacter pylori is known to be the pathogenic agent of atrophic gastritis and above all ulcer disease. It is also thought to play a role, together with other factors, in the development of stomach cancer and is currently the focus of numerous studies. In industrialised countries, infection is re...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::The prevalence of obesity has increased three-fold in the past two decades. In Europe, 150.000.000 adults and 15.000.000 children are currently affected and obesity epidemic is responsible for approximately 1,000,000 deaths annually. Bariatric surgery for the severely obese has resulted in an overall of 61% weight red...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:To evaluate antimicrobial properties of Dermacyn in abdominal infections, and to develop a new method for peritoneal lavage without using antibiotics. METHODS:One hundred and ten patients suffering from intestinal perforation (abdominal closed injury), who had been treated with opened surgical repair or par...
journal_title:Minerva chirurgica
pub_type: 杂志文章,随机对照试验
doi:10.23736/S0026-4733.16.07192-3
更新日期:2017-04-01 00:00:00
abstract::Carotid-jugular arteriovenous fistulas (AVF) are extremely rare with only 20 cases reported in the literature up to December 1996. The case of a 74-year-old man (the oldest reported in the literature) with abnormal communications between the external carotid artery and the internal jugular vein is reported. The condit...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::A dorsal formation in a newborn girl proved to have been caused by an intestinal cyst, thus forming part of the rare classification of split notochord malformations. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1975-07-15 00:00:00
abstract::The authors report 2 cases of small bowel ischemia due to unusual cause. In both cases, vasculopathy was the cause of ischemia, but with a different etiology. In the first case, a mesenteric inflammatory veno-occlusive disease, with striking features of extensive phlebitis and venulitis affecting the veins of the smal...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:The well-known soft tissue healing properties in some rat models as well as the modulating fibroblasts activity of heterologous collagen led us to the hypothesis that it is possible to prevent the peritoneal adhesions in the rat by interposition of the collagen after peritoneal surgery. METHODS:In this stud...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1998-11-01 00:00:00
abstract::Authors describe a rare case of malignant schwannoma of the omentum. The diagnosis of schwannomas is often late because of the absence of early clinical signs. Clinical, diagnostic and histopathological considerations of these neoplasias are described in this work. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::The Authors analyse 121 cases of patients affected by abdominal malignant tumors, who underwent a palliative operation. Although the number of the examinated cases is small, it appears clear that the longest survival requires, when possible, the removal of most of the malignant tissue. This seems to be in accordance w...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1979-02-15 00:00:00
abstract:AIM:Severe obesity is a major health problem affecting more than 1,000,000 people in Italy, with a 95% failure rate of nonsurgical treatments. We report our over five-years experience with laparoscopic Roux-en-Y gastric bypass (LRYGBP), evaluating the postoperative course of the patients undergoing 3 different gastro-e...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract::The authors present a clinical contribution on Paget's disease of the breast, concerning 194 cases of mammary carcinoma observed in the period 1988-1995. Treatment strategy is discussed, particularly regarding the cases without a palpable node or positive mammography that can be cured by conservative operations or, mo...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::In this paper the authors consider the problem of incisional hernias as late complications of bariatric surgery. After a description of relationships between obesity and incisional hernias they report their experience on this topic, consisting of 56 patients submitted to bilio-pancreatic diversion between March 1989 a...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-04-15 00:00:00
abstract:AIM:The aim of this study was to assess retrospectively at 5 years the clinical outcome of bone regeneration in patients who underwent maxillary sinus lift with different equine-derived, enzyme-deantigenated equine bone grafts, and simultaneous placement of acid-etched surface implants. METHODS:Eighteen patients (10 m...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract:AIM:Differentiated thyroid carcinomas (DTC) have a favourable outlook overall. Cornerstone of treatment is total thyroidectomy (TT), followed, if needed, by radiometabolic therapy. Such lesions however show a definite tendency to recur (about 35% of cases), generally in the first decade of follow-up: in 70% of patients...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract::The authors report a retrospective study of four patients treated for sigmoid volvulus at the Clinica Chirurgica II of IRCCS Policlinico S. Matteo of Pavia between April 1974 and June 1989. They are collected from a series of 74 consecutive operations for colonic obstruction not related to hernias of the inguinal-crur...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1993-05-31 00:00:00
abstract::The authors report a case of popliteal artery adventitial cystic disease. They discuss diagnosis and treatment. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::Persistent postmastectomy pain (PPMP) syndrome is characterized by neuropathic pain that develops following surgery in breast cancer patients. The reported incidence of PPMP ranges between 30% and 50% and is estimated to increase as the number of women surviving cancer continues to rise. Though effective, today's drug...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2015-04-01 00:00:00
abstract::An uncommon complication of the sigmoid diverticulitis personally observed is described. A woman, 59 years old, presented a septic shock caused by perforated sigmoid diverticulum into the space of Retzius. The diagnosis was carried out by an X-ray of the abdomen that suspected the presence of air in the retroperitoneu...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:AIM:The aim of the present study was to prospectively evaluate the Stretta radiofrequency (RF) treatment for gastroesophageal reflux disease (GERD) -related respiratory symptoms over a 5-years follow-up period. METHODS:A total of 132 patients underwent the Stretta procedure between April 2007 and February 2009; 122 of...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
abstract::Cholecystolithotomy and cholecystojejunostomy has been carried out on 11 patients with severe hypertension from cirrhosis. The indications were frequently recurring attacks of biliary cholic or acute cholecystitis at onset. There was 1 postoperative death from cardiac infarction and only minor in-hospital morbidity. N...
journal_title:Minerva chirurgica
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::Emergency surgery is required for performed colonic diverticulitis. Surgical indications are not uniform in literature. In the experience of the authors the operations have been performed in the case of peritonitis subsequent to the perforation or in the case of failure of the conservative treatment. Twenty-four patie...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::Minimally invasive colorectal surgery has evolved over the past few decades. Techniques currently in practice to decrease the impact of colorectal surgery for neoplasia include laparoscopy and its derivations, robotic surgery, transanal endoscopic surgery (TES), transanal total mesorectal excision (taTME), natural ori...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:Surgical management of external rectal prolapse (ERP) remains a challenge with the breadth of choices available and varies on the international, national, regional and locoregional level. Significant innovation has led to new techniques to manage ERP including changes to both abdominal and perineal approac...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4733.16.07205-9
更新日期:2017-02-01 00:00:00
abstract:AIM:This study reports a series of 7 patients who experienced small-bowel obstruction (SBO) after laparoscopic gastric bypass (LGBP). METHODS:Between July 2001 and June 2004, 211 patients underwent surgery for morbid obesity in 2 different institutions and 7 of them required reoperative laparoscopic surgery or laparot...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::Uremic patients in hemodialytic treatment have the same opportunity to be affected with hydatid disease as healthy people. However, because these patients usually have an immunodeficiency syndrome, it is always necessary to evaluate correctly the most common immune diagnostic procedures; furthermore the clinical appro...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Senology is going to be an independent branch, but resistances to the acknowledgement of the senologist as a devoted professional are still under way. Nevertheless, in the last 20 years an irreversible educational training was traced out. The senologist is not only the surgeon who operates on the breast: he is also a ...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:2005-12-01 00:00:00
abstract:AIM:Biliodigestive anastomoses are widely used in the treatment of biliary obstruction. METHODS:A survey is presented of the personal case series treated during the last 5 years. Thirty biliodigestive anastomose have been performed both for neoplastic disease and for benign lesions. RESULTS:The biliodigestive anastom...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00