Abstract:
:Complex diseases are far more common than diseases that follow simple Mendelian patterns of inheritance. Difficulties are experienced in the designing of experiments to dissect out the contribution of a single allele to a complex phenotype. We review the literature regarding a point mutation in methylenetetrahydrofolate reductase, a candidate gene for susceptibility to vascular diseases.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Fletcher O,Kessling AMdoi
10.1007/s004390050776subject
Has Abstractpub_date
1998-07-01 00:00:00pages
11-21issue
1eissn
0340-6717issn
1432-1203journal_volume
103pub_type
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