Quality of life and Parkinson's disease: the CR FIRST Study.

abstract：:In this study of patients with spontaneous cervical artery dissections (sCAD) we searched for mutations in ABCC6, the candidate gene for Pseudoxanthoma elasticum (PXE). Genomic DNA samples from 12 sCAD patients with pronounced electron microscopic alterations in their dermal connective tissue and from 2 patients with ...

journal_title：Journal of neurology

authors： Morcher M,Hausser I,Brandt T,Grond-Ginsbach C

更新日期：2003-08-01 00:00:00

abstract：:Multiple mononeuropathy (MM) occurs rarely during systemic lupus erythematosus (SLE) but may lead to major disability. The aim of this study was to investigate the clinic-pathological presentations of MM during SLE, as well as long-term outcomes. We conducted a multicentric retrospective study that included patients r...

journal_title：Journal of neurology

authors： Rivière E,Cohen Aubart F,Maisonobe T,Maurier F,Richez C,Gombert B,Gousseff M,Adoue D,Mathian A,Hié M,Haroche J,Amoura Z

更新日期：2017-06-01 00:00:00

abstract：:Fatigue is an important contributor to quality of life in patients who survive aneurysmal subarachnoid hemorrhage (SAH), but the determinants of this fatigue are unclear. We assessed the occurrence of fatigue 1 year after SAH and its relation to physical or cognitive impairment, passive coping, and emotional problems,...

journal_title：Journal of neurology

authors： Passier PE,Post MW,van Zandvoort MJ,Rinkel GJ,Lindeman E,Visser-Meily JM

更新日期：2011-06-01 00:00:00

abstract：:KIF1A gene encodes the kinesin 1a protein, an axonal motor protein working in cargo transport along neurites. Variants in KIF1A were identified in different forms of neurodegenerative diseases with dominant and recessive inheritance. Homozygous recessive mutations were found in the hereditary sensory and autonomic neu...

journal_title：Journal of neurology

authors： Citterio A,Arnoldi A,Panzeri E,Merlini L,D'Angelo MG,Musumeci O,Toscano A,Bondi A,Martinuzzi A,Bresolin N,Bassi MT

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Putaminal iron deposition is a histopathological feature of multiple system atrophy (MSA), which is not observed in patients with idiopathic Parkinson's disease (PD). T2*-weighted magnetic resonance imaging (MRI) gradient echo (GE) sequences are sensitive for paramagnetic susceptibility changes and therefore...

journal_title：Journal of neurology

authors： von Lewinski F,Werner C,Jörn T,Mohr A,Sixel-Döring F,Trenkwalder C

更新日期：2007-09-01 00:00:00

abstract：:The diagnosis and management of lesions of the brachial roots and of the brachial plexus is improved by appropriate investigation, both in acute and chronic disorders. The choice of investigation should be determined by the clinical problem. Since they are relatively non-invasive, electrophysiological investigations a...

journal_title：Journal of neurology

authors： Swash M

更新日期：1986-06-01 00:00:00

abstract：:There has been a resurgence in the use of functional neurosurgery for Parkinson's disease. An important factor that has played a role in this development is the recent understanding of the functional anatomy of the basal ganglia including a knowledge of the changes in the activities of neurons in the internal segment ...

journal_title：Journal of neurology

authors： Lang AE,Duff J,Saint-Cyr JA,Trepanier L,Gross RE,Lombardi W,Montgomery E,Hutchinson W,Lozano AM

更新日期：1999-09-01 00:00:00

abstract：:Cortical tubers are very common in tuberous sclerosis complex (TSC) and widely vary in size, appearance and location. The relationship between tuber features and clinical phenotype is unclear. The aim of the study is to propose a classification of tuber types along a spectrum of severity, using magnetic resonance imag...

journal_title：Journal of neurology

authors： Gallagher A,Grant EP,Madan N,Jarrett DY,Lyczkowski DA,Thiele EA

更新日期：2010-08-01 00:00:00

abstract：:The aim of this work was to determine whether survival changed during 2002-2009 at a French amyotrophic lateral sclerosis (ALS) center. We included all patients with ALS who were seen consecutively at the center from January 2002-May 2009. Participants were followed from date of first visit through death, date of cens...

journal_title：Journal of neurology

authors： Gordon PH,Salachas F,Bruneteau G,Pradat PF,Lacomblez L,Gonzalez-Bermejo J,Morelot-Panzini C,Similowski T,Elbaz A,Meininger V

更新日期：2012-09-01 00:00:00

abstract：:A comparative study of clinical and morphological findings in three fatal cases of acute necrotizing hemorrhagic encephalomyelitis (ANHE) and hyperacute experimental allergic encephalomyelitis (HEAE) in rhesus monkeys is reported. In all cases ANHE was characterized clinically by definite prodromal respiratory infecti...

journal_title：Journal of neurology

authors： Ravkina L,Harib I,Manovitch Z,Deconenko E,Letchinskaja E,Papilova E

更新日期：1979-08-01 00:00:00

abstract：:Muscle glucose-6-phosphate dehydrogenase (G6PD) deficiency is described in four clinically heterogeneous patients: an athlete who developed myoglobinuria after physical exercise; a 7-year-old, mildly mentally retarded boy, who had episodes of dark urine and high creatine kinase; and two brothers of Sardinian origin, t...

journal_title：Journal of neurology

authors： Bresolin N,Bet L,Moggio M,Meola G,Fortunato F,Comi G,Adobbati L,Geremia L,Pittalis S,Scarlato G

更新日期：1989-05-01 00:00:00

abstract：:We investigated the effect of chronic mechanical compression of the cervical spinal cord on the number of spinal accessory motoneurons in 25 tiptoe-walking Yoshimura mice. The animals had calcified deposits in the atlantoaxial membrane at the C1-C2 vertebral level, compressing the spinal cord posterolaterally. Motoneu...

journal_title：Journal of neurology

authors： Baba H,Maezawa Y,Uchida K,Imura S,Kawahara N,Tomita K,Kudo M

更新日期：1997-04-01 00:00:00

abstract：:Two siblings with Lafora disease (LD) are described: one with epilepsy, myoclonus, EEG abnormalities, severe dementia and many Lafora bodies (LBs) in muscle and skin tissue; the other with myoclonus, epilepsy, EEG abnormalities and LBs in muscle and in skin tissue, without dementia. The findings suggest that the diagn...

journal_title：Journal of neurology

authors： Iannaccone S,Zucconi M,Quattrini A,Nemni R,Comola M,Taccagni L,Smirne S

更新日期：1991-07-01 00:00:00

abstract：INTRODUCTION:Fabry disease (FD) is an X-linked lysosomal storage disorder resulting in vascular glycosphingolipid accumulation and increased stroke risk. MRI findings associated with FD include white matter hyperintensities (WMH) and cerebral microbleeds (CMBs), suggesting the presence of cerebral small vessel disease....

journal_title：Journal of neurology

authors： Lyndon D,Davagnanam I,Wilson D,Jichi F,Merwick A,Bolsover F,Jager HR,Cipolotti L,Wheeler-Kingshott C,Hughes D,Murphy E,Lachmann R,Werring DJ

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Since the detection of autoantibodies against neuronal surface antigens, autoimmune encephalitis (AE) has been more frequently diagnosed, especially in patients with symptoms typical of limbic encephalitis, such as seizures, short-term memory deficits, or psychosis. However, the clinical spectrum of AE may b...

journal_title：Journal of neurology

authors： Baumgartner A,Rauer S,Hottenrott T,Leypoldt F,Ufer F,Hegen H,Prüss H,Lewerenz J,Deisenhammer F,Stich O

更新日期：2019-01-01 00:00:00

abstract：:In vivo nuclear magnetic resonance spectroscopy (MRS) of the human brain is a recently developed technique which allows to assay noninvasively in vivo key molecules of brain metabolism. After a review of the origin of the signals detected by phosphorus and proton MRS of human brain, the impact of MRS on clinical neuro...

journal_title：Journal of neurology

authors： Vion-Dury J,Meyerhoff DJ,Cozzone PJ,Weiner MW

更新日期：1994-05-01 00:00:00

abstract：:Based on the observation of bilateral temporoparietal hypoperfusion in Alzheimer's disease (AD), single photon emission computed tomography (SPECT) is advocated by some as a powerful diagnostic tool in the evaluation of demented patients. We studied whether routine brain SPECT in elderly, mildly demented outpatients i...

journal_title：Journal of neurology

authors： Van Gool WA,Walstra GJ,Teunisse S,Van der Zant FM,Weinstein HC,Van Royen EA

更新日期：1995-06-01 00:00:00

abstract：:Two sexually active female patients presented with acute meningitis. The CSF abnormalities were severe and persistent. In spite of the absence of genital lesions, serological studies revealed a primary infection by herpes simplex virus type 2. An immunoblot study revealed intrathecal synthesis of anti-herpes antibodie...

journal_title：Journal of neurology

authors： Boucquey D,Chalon MP,Sindic CJ,Lamy ME,Laterre C

更新日期：1990-08-01 00:00:00

abstract：:The aim of our study was to compare the results obtained by intraoperative and postoperative subthalamic nucleus (STN) macrostimulation in Parkinson's disease (PD). One hundred three PD patients implanted with bilateral STN stimulation were included. The thresholds for efficacy and side effects (motor contraction; par...

journal_title：Journal of neurology

authors： Xie J,Adamec D,Decullier E,Bin-Dorel S,Mertens P,Polo G,Poisson A,Broussolle E,Thobois S

更新日期：2010-09-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy yields metabolic information and has proved to be a useful addition to structural imaging in neurological diseases. We applied short-echo time Spectroscopic Imaging in a cohort of 42 patients with secondary progressive multiple sclerosis (SPMS). Linear modelling with respect to b...

journal_title：Journal of neurology

authors： Marshall I,Thrippleton MJ,Bastin ME,Mollison D,Dickie DA,Chappell FM,Semple SIK,Cooper A,Pavitt S,Giovannoni G,Wheeler-Kingshott CAMG,Solanky BS,Weir CJ,Stallard N,Hawkins C,Sharrack B,Chataway J,Connick P,Chandran S

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The cerebellum is a predilection site of pathology in progressive multiple sclerosis (PMS) patients, contributing to cognitive deficits. Aim of this study was to investigate lobular cerebellar functional connectivity (FC) in PMS patients in relation to cognition. METHODS:In this cross-sectional study, resti...

journal_title：Journal of neurology

authors： Cocozza S,Pontillo G,Russo C,Russo CV,Costabile T,Pepe A,Tedeschi E,Lanzillo R,Brescia Morra V,Brunetti A,Inglese M,Petracca M

更新日期：2018-10-01 00:00:00

abstract：:The diagnosis of neurosarcoidosis is often difficult; the imaging signs of spinal cord sarcoidosis sometimes mimic those of cervical spondylotic myelopathy, which is common in elderly persons. We examined the characteristics of spinal cord sarcoidosis in Japanese patients with neurosarcoidosis. This case series identi...

journal_title：Journal of neurology

authors： Sakushima K,Yabe I,Nakano F,Yoshida K,Tajima Y,Houzen H,Maruo Y,Sasaki H

更新日期：2011-12-01 00:00:00

abstract：:Our knowledge of the vestibular sensory system, its functional significance for gaze and posture stabilization, and its capability to ensure accurate spatial orientation perception and spatial navigation has greatly benefitted from experimental approaches using a variety of vertebrate species. This review summarizes t...

journal_title：Journal of neurology

authors： Straka H,Zwergal A,Cullen KE

更新日期：2016-04-01 00:00:00

abstract：:We have performed genetic screening on the skeletal muscle chloride channel gene (CLCN1) in Taiwanese population. A total of four patients with myotonia congenita (MC) together with 106 normal individuals were examined. All 23 exons of the CLCN1 gene were analysed by direct sequencing of PCR products to detect the nuc...

journal_title：Journal of neurology

authors： Jou SB,Chang LI,Pan H,Chen PR,Hsiao KM

更新日期：2004-06-01 00:00:00

abstract：:Magnetisation transfer (MT) imaging provides indirect information on tissue structure abnormalities in areas that otherwise may appear normal on conventional MRI. We determined the evolution of MT changes in normal appearing white matter (NAWM) and lesion on serial examination of 9 multiple sclerosis (MS) patients and...

journal_title：Journal of neurology

authors： Laule C,Vavasour IM,Whittall KP,Oger J,Paty DW,Li DK,MacKay AL,Arnold DL

更新日期：2003-08-01 00:00:00

abstract：:Seventy-seven cases of the optic-spinal form of multiple sclerosis (OSMS) were collected from 6 institutes in 3 cities of Japan, and the clinical and MRI features were analyzed. Two-thirds of the OSMS patients had longitudinally extensive spinal cord MRI lesions (LESL), and had clinical features similar to those of re...

journal_title：Journal of neurology

authors： Nakashima I,Fukazawa T,Ota K,Nohara C,Warabi Y,Ohashi T,Miyazawa I,Fujihara K,Itoyama Y

更新日期：2007-04-01 00:00:00

abstract：:Twenty-nine cases of both clinically and neuropathologically diagnosed dementia with Lewy bodies (DLB) were retrospectively examined for autonomic symptoms. Twenty-eight cases showed some kind of autonomic dysfunction. Urinary incontinence (97 %) and constipation (83 %) were the two most common. Although urinary reten...

journal_title：Journal of neurology

authors： Horimoto Y,Matsumoto M,Akatsu H,Ikari H,Kojima K,Yamamoto T,Otsuka Y,Ojika K,Ueda R,Kosaka K

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Despite advances in the field, diagnosis and management of the wide spectrum of neurological events post allogeneic hematopoietic cell transplantation (alloHCT) remain challenging. Therefore, we investigated their incidence, diagnosis, management and long-term prognosis in alloHCT recipients. METHODS:We ret...

journal_title：Journal of neurology

authors： Sakellari I,Gavriilaki E,Papagiannopoulos S,Gavriilaki M,Batsis I,Mallouri D,Vardi A,Constantinou V,Masmanidou M,Yannaki E,Smias C,Geroukis T,Kazis D,Kimiskidis V,Anagnostopoulos A

更新日期：2019-08-01 00:00:00

abstract：:Multiple System Atrophy (MSA) and idiopathic Parkinson's disease (PD) can be difficult to distinguish. There is an ongoing debate about the diagnostic value of the growth-hormone response to clonidine (CGH-test) in PD and MSA. We investigated whether the CGH-test can identify individual patients in the early stages of...

journal_title：Journal of neurology

authors： Strijks E,van't Hof M,Sweep F,Lenders JW,Oyen WJ,Horstink MW

更新日期：2002-09-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurological disorder characterized by motor symptoms as well as severe deficits in olfactory function and microstructural changes in olfactory brain regions. Because of the evidence of asymmetric neuropathological features in early-stage PD, we examined whether lateralized mi...

journal_title：Journal of neurology

authors： Joshi N,Rolheiser TM,Fisk JD,McKelvey JR,Schoffer K,Phillips G,Armstrong M,Khan MN,Leslie RA,Rusak B,Robertson HA,Good KP

更新日期：2017-07-01 00:00:00